(data stored in ACNUC9543 zone)

SWISSPROT: Q16GV1_AEDAE

ID   Q16GV1_AEDAE            Unreviewed;       690 AA.
AC   Q16GV1;
DT   25-JUL-2006, integrated into UniProtKB/TrEMBL.
DT   25-JUL-2006, sequence version 1.
DT   08-MAY-2019, entry version 95.
DE   SubName: Full=AAEL014256-PA {ECO:0000313|EMBL:EAT33470.1};
DE   SubName: Full=ATP-dependent RNA helicase {ECO:0000313|VectorBase:AAEL014256-PA};
GN   Name=5563992 {ECO:0000313|VectorBase:AAEL014256-PA};
GN   ORFNames=AAEL014256 {ECO:0000313|EMBL:EAT33470.1};
OS   Aedes aegypti (Yellowfever mosquito) (Culex aegypti).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicoidea;
OC   Culicidae; Culicinae; Aedini; Aedes; Stegomyia.
OX   NCBI_TaxID=7159 {ECO:0000313|EMBL:EAT33470.1, ECO:0000313|Proteomes:UP000008820};
RN   [1] {ECO:0000313|EMBL:EAT33470.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Liverpool {ECO:0000313|EMBL:EAT33470.1};
RA   Loftus B.J., Nene V.M., Hannick L.I., Bidwell S., Haas B., Amedeo P.,
RA   Orvis J., Wortman J.R., White O.R., Salzberg S., Shumway M., Koo H.,
RA   Zhao Y., Holmes M., Miller J., Schatz M., Pop M., Pai G.,
RA   Utterback T., Rogers Y.-H., Kravitz S., Fraser C.M.;
RL   Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:EAT33470.1, ECO:0000313|Proteomes:UP000008820}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Liverpool {ECO:0000313|EMBL:EAT33470.1}, and Liverpool/LVPib12
RC   {ECO:0000313|Proteomes:UP000008820};
RX   PubMed=17510324; DOI=10.1126/science.1138878;
RA   Nene V., Wortman J.R., Lawson D., Haas B.J., Kodira C.D., Tu Z.J.,
RA   Loftus B.J., Xi Z., Megy K., Grabherr M., Ren Q., Zdobnov E.M.,
RA   Lobo N.F., Campbell K.S., Brown S.E., Bonaldo M.F., Zhu J.,
RA   Sinkins S.P., Hogenkamp D.G., Amedeo P., Arensburger P.,
RA   Atkinson P.W., Bidwell S.L., Biedler J., Birney E., Bruggner R.V.,
RA   Costas J., Coy M.R., Crabtree J., Crawford M., DeBruyn B.,
RA   DeCaprio D., Eiglmeier K., Eisenstadt E., El-Dorry H., Gelbart W.M.,
RA   Gomes S.L., Hammond M., Hannick L.I., Hogan J.R., Holmes M.H.,
RA   Jaffe D., Johnston S.J., Kennedy R.C., Koo H., Kravitz S.,
RA   Kriventseva E.V., Kulp D., Labutti K., Lee E., Li S., Lovin D.D.,
RA   Mao C., Mauceli E., Menck C.F., Miller J.R., Montgomery P., Mori A.,
RA   Nascimento A.L., Naveira H.F., Nusbaum C., O'Leary S.B., Orvis J.,
RA   Pertea M., Quesneville H., Reidenbach K.R., Rogers Y.-H.C., Roth C.W.,
RA   Schneider J.R., Schatz M., Shumway M., Stanke M., Stinson E.O.,
RA   Tubio J.M.C., Vanzee J.P., Verjovski-Almeida S., Werner D.,
RA   White O.R., Wyder S., Zeng Q., Zhao Q., Zhao Y., Hill C.A.,
RA   Raikhel A.S., Soares M.B., Knudson D.L., Lee N.H., Galagan J.,
RA   Salzberg S.L., Paulsen I.T., Dimopoulos G., Collins F.H., Bruce B.,
RA   Fraser-Liggett C.M., Severson D.W.;
RT   "Genome sequence of Aedes aegypti, a major arbovirus vector.";
RL   Science 316:1718-1723(2007).
RN   [3] {ECO:0000313|EMBL:EAT33470.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Liverpool {ECO:0000313|EMBL:EAT33470.1};
RG   VectorBase;
RL   Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
RN   [4] {ECO:0000313|VectorBase:AAEL014256-PA}
RP   IDENTIFICATION.
RC   STRAIN=LVP_AGWG {ECO:0000313|VectorBase:AAEL014256-PA};
RG   VectorBase;
RL   Submitted (FEB-2017) to UniProtKB.
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DR   EMBL; CH478233; EAT33470.1; -; Genomic_DNA.
DR   RefSeq; XP_001648316.1; XM_001648266.1.
DR   STRING; 7159.AAEL014256-PA; -.
DR   GeneID; 5563992; -.
DR   KEGG; aag:5563992; -.
DR   VectorBase; AAEL014256-RA; AAEL014256-PA; AAEL014256.
DR   eggNOG; KOG0922; Eukaryota.
DR   eggNOG; COG1643; LUCA.
DR   HOGENOM; HOG000175261; -.
DR   InParanoid; Q16GV1; -.
DR   KO; K17820; -.
DR   OMA; KASRAWA; -.
DR   OrthoDB; 354219at2759; -.
DR   PhylomeDB; Q16GV1; -.
DR   Proteomes; UP000008820; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   CDD; cd00079; HELICc; 1.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR011709; DUF1605.
DR   InterPro; IPR007502; Helicase-assoc_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF04408; HA2; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF07717; OB_NTP_bind; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00847; HA2; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
DR   PRODOM; Q16GV1.
DR   SWISS-2DPAGE; Q16GV1.
KW   ATP-binding {ECO:0000256|SAAS:SAAS01176619};
KW   Complete proteome {ECO:0000313|Proteomes:UP000008820};
KW   Hydrolase {ECO:0000256|SAAS:SAAS01176622};
KW   Nucleotide-binding {ECO:0000256|SAAS:SAAS01176608};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008820}.
FT   DOMAIN       49    217       Helicase ATP-binding.
FT                                {ECO:0000259|PROSITE:PS51192}.
FT   DOMAIN      241    415       Helicase C-terminal.
FT                                {ECO:0000259|PROSITE:PS51194}.
SQ   SEQUENCE   690 AA;  76802 MW;  6BBFC4402B4D03A9 CRC64;
     MKRAYPKDPG PESAESNGHP SPFRQPASTA LINQHRQSLP IYNIRKTIVD KVRECQTVIL
     IGETGSGKST QLPQYLHEAG IHGGRKIAIT QPRRVAAITV AKRVATEQGG TVGDVVGYSV
     RFEDCTSAAT KIKFMTDGTL LREALSDQLL KNYNVVILDE AHERTIATDV LFGIVKKAQS
     TRRLKMLEPL KIIIMSATMN VNHFSKYFGN CPTLYLKGKN HIVRVYQSME NMNYLEACIT
     TIFQIHEKEQ ESGDILVFLT GQEEIEATTT LVRRLAKQQV NENSLRMRVY PMYAAMSQQA
     QMDAFTPTAP NARKVILATN IAETSLTISG IKYVIDCGKA KQRAYDPLTG IDTLKVSWIS
     KAQAWQRTGR AGRLEDGFCY RTYSKSDFQA MKEHSTPEIL RCSISASTLQ LLALGIDCRE
     FDFLDKPPPE AIESALLELK NLGAINTVKA PALTALGRRM AKLPLDPKYA KIVLSAPDHN
     CLDEILTIVA MLSGENVFVN TSQRREQQLA AHSKFHAKCG DHITLLNVFK EFRTKDKSRK
     WCVDNFLLDR HLSHAASVRA QLFEICAKMG IRSNSCGNDP IPVVKCLLTG LYQNVAELQR
     DNSYLCLSNR TSARIHPSSV LCGRARPQYV LFTELVATGN RYLRTVSELE PEWIGEVAPH
     CPFLDRISSG GGGRGSTSSY AMSSSVMRTF
//

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