(data stored in ACNUC1829 zone)

SWISSPROT: Q1HRC5_AEDAE

ID   Q1HRC5_AEDAE            Unreviewed;       235 AA.
AC   Q1HRC5;
DT   13-JUN-2006, integrated into UniProtKB/TrEMBL.
DT   13-JUN-2006, sequence version 1.
DT   30-AUG-2017, entry version 84.
DE   RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};
GN   Name=5566046 {ECO:0000313|VectorBase:AAEL005137-PA};
GN   ORFNames=AAEL005137 {ECO:0000313|EMBL:EAT43417.1};
OS   Aedes aegypti (Yellowfever mosquito) (Culex aegypti).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicoidea;
OC   Culicidae; Culicinae; Aedini; Aedes; Stegomyia.
OX   NCBI_TaxID=7159 {ECO:0000313|EMBL:ABF18202.1};
RN   [1] {ECO:0000313|EMBL:EAT43417.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Liverpool {ECO:0000313|EMBL:EAT43417.1};
RA   Loftus B.J., Nene V.M., Hannick L.I., Bidwell S., Haas B., Amedeo P.,
RA   Orvis J., Wortman J.R., White O.R., Salzberg S., Shumway M., Koo H.,
RA   Zhao Y., Holmes M., Miller J., Schatz M., Pop M., Pai G.,
RA   Utterback T., Rogers Y.-H., Kravitz S., Fraser C.M.;
RL   Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ABF18202.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Ribeiro J.M.C., Chandra P.K., Calvo E., Pham V.M., Wikel S.K.;
RL   Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|EMBL:ABF18202.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=17204158; DOI=10.1186/1471-2164-8-6;
RA   Ribeiro J.M.C., Arca B., Lombardo F., Calvo E., Phan V.M.,
RA   Chandra P.K., Wikel S.K.;
RT   "An annotated catalogue of salivary gland transcripts in the adult
RT   female mosquito, Aedes aegypti.";
RL   BMC Genomics 8:6-6(2007).
RN   [4] {ECO:0000313|EMBL:EAT43417.1, ECO:0000313|Proteomes:UP000008820, ECO:0000313|VectorBase:AAEL005137-PA}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Liverpool {ECO:0000313|EMBL:EAT43417.1}, and Liverpool/LVPib12
RC   {ECO:0000313|Proteomes:UP000008820,
RC   ECO:0000313|VectorBase:AAEL005137-PA};
RX   PubMed=17510324; DOI=10.1126/science.1138878;
RA   Nene V., Wortman J.R., Lawson D., Haas B.J., Kodira C.D., Tu Z.J.,
RA   Loftus B.J., Xi Z., Megy K., Grabherr M., Ren Q., Zdobnov E.M.,
RA   Lobo N.F., Campbell K.S., Brown S.E., Bonaldo M.F., Zhu J.,
RA   Sinkins S.P., Hogenkamp D.G., Amedeo P., Arensburger P.,
RA   Atkinson P.W., Bidwell S.L., Biedler J., Birney E., Bruggner R.V.,
RA   Costas J., Coy M.R., Crabtree J., Crawford M., DeBruyn B.,
RA   DeCaprio D., Eiglmeier K., Eisenstadt E., El-Dorry H., Gelbart W.M.,
RA   Gomes S.L., Hammond M., Hannick L.I., Hogan J.R., Holmes M.H.,
RA   Jaffe D., Johnston S.J., Kennedy R.C., Koo H., Kravitz S.,
RA   Kriventseva E.V., Kulp D., Labutti K., Lee E., Li S., Lovin D.D.,
RA   Mao C., Mauceli E., Menck C.F., Miller J.R., Montgomery P., Mori A.,
RA   Nascimento A.L., Naveira H.F., Nusbaum C., O'Leary S.B., Orvis J.,
RA   Pertea M., Quesneville H., Reidenbach K.R., Rogers Y.-H.C., Roth C.W.,
RA   Schneider J.R., Schatz M., Shumway M., Stanke M., Stinson E.O.,
RA   Tubio J.M.C., Vanzee J.P., Verjovski-Almeida S., Werner D.,
RA   White O.R., Wyder S., Zeng Q., Zhao Q., Zhao Y., Hill C.A.,
RA   Raikhel A.S., Soares M.B., Knudson D.L., Lee N.H., Galagan J.,
RA   Salzberg S.L., Paulsen I.T., Dimopoulos G., Collins F.H., Bruce B.,
RA   Fraser-Liggett C.M., Severson D.W.;
RT   "Genome sequence of Aedes aegypti, a major arbovirus vector.";
RL   Science 316:1718-1723(2007).
RN   [5] {ECO:0000313|EMBL:EAT43417.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Liverpool {ECO:0000313|EMBL:EAT43417.1};
RG   VectorBase;
RL   Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
RN   [6] {ECO:0000313|VectorBase:AAEL005137-PA}
RP   IDENTIFICATION.
RC   STRAIN=Liverpool/LVPib12 {ECO:0000313|VectorBase:AAEL005137-PA};
RG   VectorBase;
RL   Submitted (FEB-2017) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU361218};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU361218}.
CC   -!- SIMILARITY: Belongs to the tetraspanin (TM4SF) family.
CC       {ECO:0000256|RuleBase:RU361218, ECO:0000256|SAAS:SAAS00545671}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; DQ440169; ABF18202.1; -; mRNA.
DR   EMBL; CH477328; EAT43417.1; -; Genomic_DNA.
DR   RefSeq; XP_001650414.1; XM_001650364.1.
DR   UniGene; Aae.4329; -.
DR   STRING; 7159.AAEL005137-PA; -.
DR   EnsemblMetazoa; AAEL005137-RA; AAEL005137-PA; AAEL005137.
DR   GeneID; 5566046; -.
DR   KEGG; aag:AaeL_AAEL005137; -.
DR   VectorBase; AAEL005137-RA; AAEL005137-PA; AAEL005137.
DR   eggNOG; KOG3882; Eukaryota.
DR   eggNOG; ENOG4111IRY; LUCA.
DR   HOGENOM; HOG000230651; -.
DR   KO; K17352; -.
DR   OMA; MLLTYFI; -.
DR   OrthoDB; EOG091G0JM9; -.
DR   Proteomes; UP000008820; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.1450.10; -; 1.
DR   InterPro; IPR000301; Tetraspanin.
DR   InterPro; IPR018499; Tetraspanin/Peripherin.
DR   InterPro; IPR008952; Tetraspanin_EC2.
DR   Pfam; PF00335; Tetraspannin; 1.
DR   PIRSF; PIRSF002419; Tetraspanin; 1.
DR   PRINTS; PR00259; TMFOUR.
DR   SUPFAM; SSF48652; SSF48652; 1.
PE   2: Evidence at transcript level;
DR   PRODOM; Q1HRC5.
DR   SWISS-2DPAGE; Q1HRC5.
KW   Complete proteome {ECO:0000313|Proteomes:UP000008820};
KW   Membrane {ECO:0000256|RuleBase:RU361218,
KW   ECO:0000256|SAAS:SAAS00027997};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008820};
KW   Transmembrane {ECO:0000256|RuleBase:RU361218,
KW   ECO:0000256|SAAS:SAAS00429797};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU361218,
KW   ECO:0000256|SAAS:SAAS00028005}.
FT   TRANSMEM     16     38       Helical. {ECO:0000256|RuleBase:RU361218}.
FT   TRANSMEM     58     81       Helical. {ECO:0000256|RuleBase:RU361218}.
FT   TRANSMEM     88    112       Helical. {ECO:0000256|RuleBase:RU361218}.
FT   TRANSMEM    206    231       Helical. {ECO:0000256|RuleBase:RU361218}.
SQ   SEQUENCE   235 AA;  26214 MW;  71A112157533F7D7 CRC64;
     MGLGGRMDCC GQCVKYSMFV SNFIIFIGGA IVFGLGVWTV VDKNFINELL GTNLFSGAVY
     VLIATSALVC LLSFFGCIGA AKEYKCMLLT YFILIFLIFV TMLIGGILGY VFREKVSQTM
     QQEMHSSMTF YGAYGKRSIT QAWDMTQERL KCCGVKHYND WRGSIPQSCC QKTFTDYKPC
     QDHPTPENIY IQGCLDITSN LIRDNAAFIG ASGIIVAILL IFGMIFSCSL FRMIE
//

If you have problems or comments...

PBIL Back to PBIL home page