(data stored in ACNUC404 zone)

SWISSPROT: F6P9S6_DANRE

ID   F6P9S6_DANRE            Unreviewed;       428 AA.
AC   F6P9S6; Q1LXV4;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   08-MAY-2019, entry version 29.
DE   SubName: Full=Si:ch211-243g18.2 {ECO:0000313|EMBL:AAI62170.1, ECO:0000313|Ensembl:ENSDARP00000031042};
GN   Name=si:ch211-243g18.2 {ECO:0000313|EMBL:AAI62170.1,
GN   ECO:0000313|Ensembl:ENSDARP00000031042,
GN   ECO:0000313|ZFIN:ZDB-GENE-030131-2830};
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Cyprinidae; Danio.
OX   NCBI_TaxID=7955 {ECO:0000313|Ensembl:ENSDARP00000031042, ECO:0000313|Proteomes:UP000000437};
RN   [1] {ECO:0000313|EMBL:AAI62170.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSDARP00000031042}
RP   IDENTIFICATION.
RC   STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000031042};
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
RN   [3] {ECO:0000313|Ensembl:ENSDARP00000031042, ECO:0000313|Proteomes:UP000000437}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000031042,
RC   ECO:0000313|Proteomes:UP000000437};
RX   PubMed=23594743; DOI=10.1038/nature12111;
RA   Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C.,
RA   Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L.,
RA   McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C.,
RA   Koch R., Rauch G.J., White S., Chow W., Kilian B., Quintais L.T.,
RA   Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T.,
RA   Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F.,
RA   Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H.,
RA   Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA   Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA   Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA   Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA   Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J.,
RA   Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P.,
RA   Barker N., Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G.,
RA   Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D.,
RA   Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K.,
RA   Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C.,
RA   Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J.,
RA   Murnane C., Gray E., Humphries M., Sycamore N., Barker D.,
RA   Saunders D., Wallis J., Babbage A., Hammond S.,
RA   Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A.,
RA   Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA   Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA   Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D.,
RA   Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z.,
RA   Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J.,
RA   Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C.,
RA   Raddatz G., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C.,
RA   Yang F., Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J.,
RA   Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C.,
RA   Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H.,
RA   Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J.,
RA   Stemple D.L.;
RT   "The zebrafish reference genome sequence and its relationship to the
RT   human genome.";
RL   Nature 496:498-503(2013).
RN   [4] {ECO:0000313|Ensembl:ENSDARP00000064976}
RP   IDENTIFICATION.
RC   STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000064976};
RG   Ensembl;
RL   Submitted (AUG-2013) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the intermediate filament family.
CC       {ECO:0000256|PROSITE-ProRule:PRU01188,
CC       ECO:0000256|RuleBase:RU000685, ECO:0000256|SAAS:SAAS01036505}.
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DR   EMBL; BX248511; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BC162170; AAI62170.1; -; mRNA.
DR   EMBL; BC162525; AAI62525.1; -; mRNA.
DR   RefSeq; NP_001038375.1; NM_001044910.1.
DR   Ensembl; ENSDART00000028855; ENSDARP00000031042; ENSDARG00000044261.
DR   Ensembl; ENSDART00000064977; ENSDARP00000064976; ENSDARG00000044261.
DR   GeneID; 559906; -.
DR   KEGG; dre:559906; -.
DR   ZFIN; ZDB-GENE-030131-2830; si:ch211-243g18.2.
DR   eggNOG; ENOG410J8WE; Eukaryota.
DR   eggNOG; ENOG410YB16; LUCA.
DR   GeneTree; ENSGT00950000182969; -.
DR   HOGENOM; HOG000230975; -.
DR   OrthoDB; 769200at2759; -.
DR   TreeFam; TF332742; -.
DR   Proteomes; UP000000437; Chromosome 10.
DR   Bgee; ENSDARG00000044261; Expressed in 17 organ(s), highest expression level in caudal fin.
DR   GO; GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
DR   GO; GO:0005198; F:structural molecule activity; IEA:UniProtKB-UniRule.
DR   InterPro; IPR018039; IF_conserved.
DR   InterPro; IPR039008; IF_rod_dom.
DR   InterPro; IPR002957; Keratin_I.
DR   PANTHER; PTHR23239; PTHR23239; 1.
DR   Pfam; PF00038; Filament; 1.
DR   PRINTS; PR01248; TYPE1KERATIN.
DR   SMART; SM01391; Filament; 1.
DR   PROSITE; PS00226; IF_ROD_1; 1.
DR   PROSITE; PS51842; IF_ROD_2; 1.
PE   1: Evidence at protein level;
DR   PRODOM; F6P9S6.
DR   SWISS-2DPAGE; F6P9S6.
KW   Coiled coil {ECO:0000256|PROSITE-ProRule:PRU01188,
KW   ECO:0000256|SAAS:SAAS01036532, ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000437};
KW   Intermediate filament {ECO:0000256|PROSITE-ProRule:PRU01188,
KW   ECO:0000256|RuleBase:RU000685, ECO:0000256|SAAS:SAAS01036494};
KW   Proteomics identification {ECO:0000213|PeptideAtlas:F6P9S6};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000437}.
FT   DOMAIN       72    383       IF rod. {ECO:0000259|PROSITE:PS51842}.
FT   COILED       76    110       {ECO:0000256|SAM:Coils}.
FT   COILED      118    138       {ECO:0000256|SAM:Coils}.
FT   COILED      188    226       {ECO:0000256|SAM:Coils}.
FT   COILED      267    287       {ECO:0000256|SAM:Coils}.
FT   COILED      295    382       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   428 AA;  48572 MW;  58877DB186A2F9F3 CRC64;
     MSSSLSVRSL SLGRQPSFSS MSLRDSGRAR SKAAVSFAAA KPLSRSSSMS MSDLNGLGSM
     SLNGLHGNST NEKEAMQSLN SRLANYLDKV RSLEKSNADL ELRLKQLMLD RVPKGHDIDS
     MMAQAHALEQ EVRKKTLENA RIMLEIDNAK LAADDFRIKW ETESAMCQSV ERDCVALKKA
     KSDHDQIIAT LRGDLDSLKE ELYFLRKNHE EEMDSLRARI AQEDVNVEVD AARGPELGTV
     LSDLRSQYEG IVQKNKEEAE SWYRKKLETV QTQVRESNEA LRGAQSELTE RQRFLQTLEV
     ELESLHKQVA ALEGNLSETG QKYTLEMERL QATLAQLEDS LSQLRLDMQR NKTDYEQLLR
     IKQNLEMEIA TYRRLLEGEE TVKEIPPPPK KEPDVRTRKI VKVVTQTMIN GKVVDESSEV
     EQIEETKK
//

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