(data stored in SCRATCH zone)

SWISSPROT: Q2ILW0_ANADE

ID   Q2ILW0_ANADE            Unreviewed;       301 AA.
AC   Q2ILW0;
DT   07-MAR-2006, integrated into UniProtKB/TrEMBL.
DT   07-MAR-2006, sequence version 1.
DT   08-MAY-2019, entry version 87.
DE   RecName: Full=Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase {ECO:0000256|HAMAP-Rule:MF_01147, ECO:0000256|SAAS:SAAS01134355};
DE            EC=2.5.1.145 {ECO:0000256|HAMAP-Rule:MF_01147, ECO:0000256|SAAS:SAAS01134353};
GN   Name=lgt {ECO:0000256|HAMAP-Rule:MF_01147};
GN   OrderedLocusNames=Adeh_0014 {ECO:0000313|EMBL:ABC79792.1};
OS   Anaeromyxobacter dehalogenans (strain 2CP-C).
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Myxococcales;
OC   Cystobacterineae; Anaeromyxobacteraceae; Anaeromyxobacter.
OX   NCBI_TaxID=290397 {ECO:0000313|EMBL:ABC79792.1, ECO:0000313|Proteomes:UP000001935};
RN   [1] {ECO:0000313|EMBL:ABC79792.1, ECO:0000313|Proteomes:UP000001935}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=2CP-C {ECO:0000313|EMBL:ABC79792.1,
RC   ECO:0000313|Proteomes:UP000001935};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Brettin T., Bruce D., Han C.,
RA   Tapia R., Gilna P., Kiss H., Schmutz J., Larimer F., Land M.,
RA   Kyrpides N., Anderson I., Sanford R.A., Ritalahti K.M., Thomas H.S.,
RA   Kirby J.R., Zhulin I.B., Loeffler F.E., Richardson P.;
RT   "Complete sequence of Anaeromyxobacter dehalogenans 2CP-C.";
RL   Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Proteomes:UP000001935}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=2CP-C {ECO:0000313|Proteomes:UP000001935};
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Brettin T., Bruce D., Han C.,
RA   Tapia R., Gilna P., Kiss H., Schmutz J., Larimer F., Land M.,
RA   Kyrpides N., Anderson I., Sanford R.A., Ritalahti K.M., Thomas H.S.,
RA   Kirby J.R., Zhulin I.B., Loeffler F.E., Richardson P.;
RT   "Complete sequence of Anaeromyxobacter dehalogenans 2CP-C.";
RL   Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Catalyzes the transfer of the diacylglyceryl group from
CC       phosphatidylglycerol to the sulfhydryl group of the N-terminal
CC       cysteine of a prolipoprotein, the first step in the formation of
CC       mature lipoproteins. {ECO:0000256|HAMAP-Rule:MF_01147,
CC       ECO:0000256|SAAS:SAAS01134350}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + L-
CC         cysteinyl-[prolipoprotein] = H(+) + S-1,2-diacyl-sn-glyceryl-L-
CC         cysteinyl-[prolipoprotein] + sn-glycerol 1-phosphate;
CC         Xref=Rhea:RHEA:56712, Rhea:RHEA-COMP:14679, Rhea:RHEA-
CC         COMP:14680, ChEBI:CHEBI:15378, ChEBI:CHEBI:29950,
CC         ChEBI:CHEBI:57685, ChEBI:CHEBI:64716, ChEBI:CHEBI:140658;
CC         EC=2.5.1.145; Evidence={ECO:0000256|HAMAP-Rule:MF_01147,
CC         ECO:0000256|SAAS:SAAS01134354};
CC   -!- PATHWAY: Protein modification; lipoprotein biosynthesis
CC       (diacylglyceryl transfer). {ECO:0000256|HAMAP-Rule:MF_01147,
CC       ECO:0000256|SAAS:SAAS00704521}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000256|HAMAP-
CC       Rule:MF_01147}; Multi-pass membrane protein {ECO:0000256|HAMAP-
CC       Rule:MF_01147}.
CC   -!- SIMILARITY: Belongs to the Lgt family. {ECO:0000256|HAMAP-
CC       Rule:MF_01147, ECO:0000256|SAAS:SAAS00704541}.
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DR   EMBL; CP000251; ABC79792.1; -; Genomic_DNA.
DR   RefSeq; WP_011419075.1; NC_007760.1.
DR   STRING; 290397.Adeh_0014; -.
DR   EnsemblBacteria; ABC79792; ABC79792; Adeh_0014.
DR   KEGG; ade:Adeh_0014; -.
DR   eggNOG; ENOG4107X0M; Bacteria.
DR   eggNOG; COG0682; LUCA.
DR   HOGENOM; HOG000098666; -.
DR   KO; K13292; -.
DR   OMA; AIRWYGL; -.
DR   BioCyc; ADEH290397:G1G5W-15-MONOMER; -.
DR   UniPathway; UPA00664; -.
DR   Proteomes; UP000001935; Chromosome.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0008961; F:phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0042158; P:lipoprotein biosynthetic process; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01147; Lgt; 1.
DR   InterPro; IPR001640; lgt.
DR   PANTHER; PTHR30589; PTHR30589; 1.
DR   Pfam; PF01790; LGT; 1.
DR   TIGRFAMs; TIGR00544; lgt; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q2ILW0.
DR   SWISS-2DPAGE; Q2ILW0.
KW   Cell inner membrane {ECO:0000256|HAMAP-Rule:MF_01147};
KW   Cell membrane {ECO:0000256|HAMAP-Rule:MF_01147,
KW   ECO:0000256|SAAS:SAAS00704533};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001935};
KW   Lipoprotein {ECO:0000313|EMBL:ABC79792.1};
KW   Membrane {ECO:0000256|HAMAP-Rule:MF_01147,
KW   ECO:0000256|SAAS:SAAS00704538};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001935};
KW   Transferase {ECO:0000256|HAMAP-Rule:MF_01147,
KW   ECO:0000256|SAAS:SAAS00704540, ECO:0000313|EMBL:ABC79792.1};
KW   Transmembrane {ECO:0000256|HAMAP-Rule:MF_01147,
KW   ECO:0000256|SAAS:SAAS00704539};
KW   Transmembrane helix {ECO:0000256|HAMAP-Rule:MF_01147,
KW   ECO:0000256|SAAS:SAAS00704519}.
FT   TRANSMEM     20     37       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_01147}.
FT   TRANSMEM     49     69       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_01147}.
FT   TRANSMEM     97    120       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_01147}.
FT   TRANSMEM    228    247       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_01147}.
FT   TRANSMEM    259    281       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_01147}.
FT   BINDING     146    146       Lipid substrate. {ECO:0000256|HAMAP-Rule:
FT                                MF_01147}.
SQ   SEQUENCE   301 AA;  32763 MW;  276DEA25A92FE71B CRC64;
     MLPVLFRIPL PGGASLPLHT YGLLIAIGFM VGIWLAQREA VRRGQDPRRL ADLAFWILVS
     ALVGSRVYYM LVNPGEFFSP ARFLVETPFG RIPRVLAIWQ GGLVFYGGFI GAALTAAWYL
     RRHRMGFLEH ADTLIPSVAL GHFFGRLGCF GAGCCWGDVA HGHLPWAARF PPESLAFQSF
     ADRPDPGQYL APDRLATLPL HPTQLYEAFG ELGLFLLLVL VVRPRKRFHG QVLAAWLMLY
     AVLRTGVEAF RGDVERGVIL GLGVGQWTSI AIFAAGATVW ARARRPAPAG AGPAAAPAGG
     R
//

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