(data stored in SCRATCH zone)

SWISSPROT: Q2IMR6_ANADE

ID   Q2IMR6_ANADE            Unreviewed;       150 AA.
AC   Q2IMR6;
DT   07-MAR-2006, integrated into UniProtKB/TrEMBL.
DT   07-MAR-2006, sequence version 1.
DT   08-MAY-2019, entry version 94.
DE   RecName: Full=Peptide methionine sulfoxide reductase MsrB {ECO:0000256|HAMAP-Rule:MF_01400};
DE            EC=1.8.4.12 {ECO:0000256|HAMAP-Rule:MF_01400};
DE   AltName: Full=Peptide-methionine (R)-S-oxide reductase {ECO:0000256|HAMAP-Rule:MF_01400};
GN   Name=msrB {ECO:0000256|HAMAP-Rule:MF_01400};
GN   OrderedLocusNames=Adeh_0325 {ECO:0000313|EMBL:ABC80101.1};
OS   Anaeromyxobacter dehalogenans (strain 2CP-C).
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Myxococcales;
OC   Cystobacterineae; Anaeromyxobacteraceae; Anaeromyxobacter.
OX   NCBI_TaxID=290397 {ECO:0000313|EMBL:ABC80101.1, ECO:0000313|Proteomes:UP000001935};
RN   [1] {ECO:0000313|Proteomes:UP000001935}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=2CP-C {ECO:0000313|Proteomes:UP000001935};
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Brettin T., Bruce D., Han C.,
RA   Tapia R., Gilna P., Kiss H., Schmutz J., Larimer F., Land M.,
RA   Kyrpides N., Anderson I., Sanford R.A., Ritalahti K.M., Thomas H.S.,
RA   Kirby J.R., Zhulin I.B., Loeffler F.E., Richardson P.;
RT   "Complete sequence of Anaeromyxobacter dehalogenans 2CP-C.";
RL   Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=[thioredoxin]-disulfide + H2O + L-methionyl-[protein] =
CC         [thioredoxin]-dithiol + L-methionyl-(R)-S-oxide-[protein];
CC         Xref=Rhea:RHEA:24164, Rhea:RHEA-COMP:10698, Rhea:RHEA-
CC         COMP:10700, Rhea:RHEA-COMP:12313, Rhea:RHEA-COMP:12314,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:16044, ChEBI:CHEBI:29950,
CC         ChEBI:CHEBI:45764, ChEBI:CHEBI:50058; EC=1.8.4.12;
CC         Evidence={ECO:0000256|HAMAP-Rule:MF_01400,
CC         ECO:0000256|SAAS:SAAS01165063};
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence={ECO:0000256|HAMAP-
CC         Rule:MF_01400};
CC       Note=Binds 1 zinc ion per subunit. The zinc ion is important for
CC       the structural integrity of the protein. {ECO:0000256|HAMAP-
CC       Rule:MF_01400};
CC   -!- SIMILARITY: Belongs to the MsrB Met sulfoxide reductase family.
CC       {ECO:0000256|HAMAP-Rule:MF_01400, ECO:0000256|SAAS:SAAS01165053}.
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DR   EMBL; CP000251; ABC80101.1; -; Genomic_DNA.
DR   STRING; 290397.Adeh_0325; -.
DR   EnsemblBacteria; ABC80101; ABC80101; Adeh_0325.
DR   KEGG; ade:Adeh_0325; -.
DR   eggNOG; ENOG4105E0X; Bacteria.
DR   eggNOG; COG0229; LUCA.
DR   HOGENOM; HOG000243424; -.
DR   KO; K07305; -.
DR   OMA; CNTCDAH; -.
DR   Proteomes; UP000001935; Chromosome.
DR   GO; GO:0033743; F:peptide-methionine (R)-S-oxide reductase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01400; MsrB; 1.
DR   InterPro; IPR028427; Met_Sox_Rdtase.
DR   InterPro; IPR002579; Met_Sox_Rdtase_MsrB.
DR   InterPro; IPR011057; Mss4-like_sf.
DR   PANTHER; PTHR10173; PTHR10173; 1.
DR   Pfam; PF01641; SelR; 1.
DR   SUPFAM; SSF51316; SSF51316; 1.
DR   TIGRFAMs; TIGR00357; TIGR00357; 1.
DR   PROSITE; PS51790; MSRB; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q2IMR6.
DR   SWISS-2DPAGE; Q2IMR6.
KW   Complete proteome {ECO:0000313|Proteomes:UP000001935};
KW   Metal-binding {ECO:0000256|HAMAP-Rule:MF_01400};
KW   Oxidoreductase {ECO:0000256|HAMAP-Rule:MF_01400,
KW   ECO:0000256|SAAS:SAAS01165056, ECO:0000313|EMBL:ABC80101.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001935};
KW   Zinc {ECO:0000256|HAMAP-Rule:MF_01400}.
FT   DOMAIN       18    140       MsrB. {ECO:0000259|PROSITE:PS51790}.
FT   ACT_SITE    129    129       Nucleophile. {ECO:0000256|HAMAP-Rule:
FT                                MF_01400}.
FT   METAL        57     57       Zinc. {ECO:0000256|HAMAP-Rule:MF_01400}.
FT   METAL        60     60       Zinc. {ECO:0000256|HAMAP-Rule:MF_01400}.
FT   METAL       106    106       Zinc. {ECO:0000256|HAMAP-Rule:MF_01400}.
FT   METAL       109    109       Zinc. {ECO:0000256|HAMAP-Rule:MF_01400}.
SQ   SEQUENCE   150 AA;  16287 MW;  1D6342315EA28693 CRC64;
     MGRSTAREAR MDKLILSDAE WRDRLTPEQY QVLRGHGTEP PGTGCFLGTH EPGTYVCAGC
     GNPLFRSGEK FESGTGWPSF TRPVSEEAVV EVHDRSYGMR RTEVRCARCD GHLGHVFPDG
     PPPTGLRYCM NSAAMQHVPE GAPLDAPGGG
//

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