(data stored in SCRATCH zone)

SWISSPROT: Q2IMV2_ANADE

ID   Q2IMV2_ANADE            Unreviewed;       390 AA.
AC   Q2IMV2;
DT   07-MAR-2006, integrated into UniProtKB/TrEMBL.
DT   07-MAR-2006, sequence version 1.
DT   08-MAY-2019, entry version 79.
DE   SubName: Full=3-ketoacyl-CoA thiolase {ECO:0000313|EMBL:ABC80135.1};
DE            EC=2.3.1.16 {ECO:0000313|EMBL:ABC80135.1};
GN   OrderedLocusNames=Adeh_0359 {ECO:0000313|EMBL:ABC80135.1};
OS   Anaeromyxobacter dehalogenans (strain 2CP-C).
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Myxococcales;
OC   Cystobacterineae; Anaeromyxobacteraceae; Anaeromyxobacter.
OX   NCBI_TaxID=290397 {ECO:0000313|EMBL:ABC80135.1, ECO:0000313|Proteomes:UP000001935};
RN   [1] {ECO:0000313|Proteomes:UP000001935}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=2CP-C {ECO:0000313|Proteomes:UP000001935};
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Brettin T., Bruce D., Han C.,
RA   Tapia R., Gilna P., Kiss H., Schmutz J., Larimer F., Land M.,
RA   Kyrpides N., Anderson I., Sanford R.A., Ritalahti K.M., Thomas H.S.,
RA   Kirby J.R., Zhulin I.B., Loeffler F.E., Richardson P.;
RT   "Complete sequence of Anaeromyxobacter dehalogenans 2CP-C.";
RL   Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the thiolase family.
CC       {ECO:0000256|RuleBase:RU003557}.
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DR   EMBL; CP000251; ABC80135.1; -; Genomic_DNA.
DR   RefSeq; WP_011419418.1; NC_007760.1.
DR   STRING; 290397.Adeh_0359; -.
DR   EnsemblBacteria; ABC80135; ABC80135; Adeh_0359.
DR   KEGG; ade:Adeh_0359; -.
DR   eggNOG; ENOG4105CHU; Bacteria.
DR   eggNOG; COG0183; LUCA.
DR   HOGENOM; HOG000012239; -.
DR   KO; K00632; -.
DR   OMA; DYYWGMG; -.
DR   BioCyc; ADEH290397:G1G5W-369-MONOMER; -.
DR   Proteomes; UP000001935; Chromosome.
DR   GO; GO:0003988; F:acetyl-CoA C-acyltransferase activity; IEA:UniProtKB-EC.
DR   CDD; cd00751; thiolase; 1.
DR   Gene3D; 3.40.47.10; -; 2.
DR   InterPro; IPR002155; Thiolase.
DR   InterPro; IPR016039; Thiolase-like.
DR   InterPro; IPR020615; Thiolase_acyl_enz_int_AS.
DR   InterPro; IPR020610; Thiolase_AS.
DR   InterPro; IPR020617; Thiolase_C.
DR   InterPro; IPR020613; Thiolase_CS.
DR   InterPro; IPR020616; Thiolase_N.
DR   Pfam; PF02803; Thiolase_C; 1.
DR   Pfam; PF00108; Thiolase_N; 1.
DR   PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR   SUPFAM; SSF53901; SSF53901; 2.
DR   TIGRFAMs; TIGR01930; AcCoA-C-Actrans; 1.
DR   PROSITE; PS00098; THIOLASE_1; 1.
DR   PROSITE; PS00737; THIOLASE_2; 1.
DR   PROSITE; PS00099; THIOLASE_3; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q2IMV2.
DR   SWISS-2DPAGE; Q2IMV2.
KW   Acyltransferase {ECO:0000256|RuleBase:RU003557,
KW   ECO:0000313|EMBL:ABC80135.1};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001935};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001935};
KW   Transferase {ECO:0000256|RuleBase:RU003557,
KW   ECO:0000313|EMBL:ABC80135.1}.
FT   DOMAIN        5    259       Thiolase_N. {ECO:0000259|Pfam:PF00108}.
FT   DOMAIN      268    389       Thiolase_C. {ECO:0000259|Pfam:PF02803}.
FT   ACT_SITE     90     90       Acyl-thioester intermediate.
FT                                {ECO:0000256|PIRSR:PIRSR000429-1}.
FT   ACT_SITE    346    346       Proton acceptor. {ECO:0000256|PIRSR:
FT                                PIRSR000429-1}.
FT   ACT_SITE    376    376       Proton acceptor. {ECO:0000256|PIRSR:
FT                                PIRSR000429-1}.
SQ   SEQUENCE   390 AA;  39755 MW;  C8FDF699F0310ACD CRC64;
     MSAAYVLAAV RTPGCKAKKG KLKDVRPDDL AAVAIRALLA RTGVEPGQVE DVILGCAFPE
     GEQGMNLGRV AALRAGLPVG VPGQTVNRFC ASGLQSIATA AERIMAGQAD CIVAGGAESM
     SLVPMGGSHF SANPSLVASW PESFAAMGIT AELVAARDHV SREDQDAFAV ASHARAARAQ
     AEGLFADELV PVEVEQVTVE KGKAVRRTEQ VTADDGVRPG TSLEALARLK PAFKIDGTVT
     AGNASQTTDG AAAALVVSEA FLSRTGLAPL ARFVSYAVRG VPPEIMGIGP VEAIPAALKR
     AGLRVEDVGQ IELNEAFAAQ SLACMRALGL DPAKVNPTGG AIALGHPLGC TGAKLTATLL
     HGLRRTGARH GIVSMCVGGG MGAAAVFERA
//

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