(data stored in ACNUC7421 zone)

SWISSPROT: ECHD2_BOVIN

ID   ECHD2_BOVIN             Reviewed;         296 AA.
AC   Q2TBT3;
DT   13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT   24-JAN-2006, sequence version 1.
DT   30-AUG-2017, entry version 79.
DE   RecName: Full=Enoyl-CoA hydratase domain-containing protein 2, mitochondrial;
DE   Flags: Precursor;
GN   Name=ECHDC2;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;
OC   Pecora; Bovidae; Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Liver;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the enoyl-CoA hydratase/isomerase family.
CC       {ECO:0000305}.
DR   EMBL; BC109686; AAI09687.1; -; mRNA.
DR   RefSeq; NP_001033625.1; NM_001038536.2.
DR   UniGene; Bt.5885; -.
DR   ProteinModelPortal; Q2TBT3; -.
DR   SMR; Q2TBT3; -.
DR   STRING; 9913.ENSBTAP00000003779; -.
DR   PaxDb; Q2TBT3; -.
DR   PeptideAtlas; Q2TBT3; -.
DR   PRIDE; Q2TBT3; -.
DR   Ensembl; ENSBTAT00000003779; ENSBTAP00000003779; ENSBTAG00000002910.
DR   GeneID; 513795; -.
DR   KEGG; bta:513795; -.
DR   CTD; 55268; -.
DR   eggNOG; KOG1679; Eukaryota.
DR   eggNOG; COG1024; LUCA.
DR   GeneTree; ENSGT00890000139344; -.
DR   HOGENOM; HOG000027939; -.
DR   HOVERGEN; HBG106714; -.
DR   InParanoid; Q2TBT3; -.
DR   OMA; RENATIY; -.
DR   OrthoDB; EOG091G0Q9K; -.
DR   TreeFam; TF314276; -.
DR   Proteomes; UP000009136; Chromosome 3.
DR   Bgee; ENSBTAG00000002910; -.
DR   GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR   GO; GO:0004300; F:enoyl-CoA hydratase activity; IBA:GO_Central.
DR   GO; GO:0006635; P:fatty acid beta-oxidation; IBA:GO_Central.
DR   Gene3D; 1.10.12.10; -; 1.
DR   InterPro; IPR029045; ClpP/crotonase-like_dom.
DR   InterPro; IPR014748; Crontonase_C.
DR   InterPro; IPR001753; Crotonase_core_superfam.
DR   InterPro; IPR018376; Enoyl-CoA_hyd/isom_CS.
DR   Pfam; PF00378; ECH_1; 1.
DR   SUPFAM; SSF52096; SSF52096; 1.
DR   PROSITE; PS00166; ENOYL_COA_HYDRATASE; 1.
PE   2: Evidence at transcript level;
DR   PRODOM; Q2TBT3.
DR   SWISS-2DPAGE; Q2TBT3.
KW   Acetylation; Complete proteome; Fatty acid metabolism;
KW   Lipid metabolism; Lyase; Mitochondrion; Reference proteome;
KW   Transit peptide.
FT   TRANSIT       1      ?       Mitochondrion. {ECO:0000255}.
FT   CHAIN         ?    296       Enoyl-CoA hydratase domain-containing
FT                                protein 2, mitochondrial.
FT                                /FTId=PRO_0000309458.
FT   SITE        146    146       Important for catalytic activity.
FT                                {ECO:0000250}.
FT   SITE        166    166       Important for catalytic activity.
FT                                {ECO:0000250}.
FT   MOD_RES     101    101       N6-acetyllysine; alternate.
FT                                {ECO:0000250|UniProtKB:Q3TLP5}.
FT   MOD_RES     101    101       N6-succinyllysine; alternate.
FT                                {ECO:0000250|UniProtKB:Q3TLP5}.
SQ   SEQUENCE   296 AA;  31604 MW;  D47698D2A19E8CD3 CRC64;
     MLRVLTSTLR FPRPWKPLET RGCSSNPGAA GREIQVCALA GPNQGIAEIL MNRPSARNAL
     GNVFVSQLLE ALAQLREDRQ VRVLIFRSGV KGVFCAGADL KEREQMSEAE VGLFVQRLRG
     LMTEIAAFPA PTIAAMDGFA LGGGLELALA CDLRVAASSA VMGLIETTRG LLPGAGGTQR
     LPRCLGVALA KELIFTGRRL SGAQAQALGL VNHAVAQNEE GNAAYHRARA LAQEILPQAP
     IAVRLSKVAI DRGIEVDIAS GMAIEGICYA QNIPTRDRLE GMAAFREKRL PRFVGE
//

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