(data stored in SCRATCH zone)

SWISSPROT: Q3IDS2_PSEHT

ID   Q3IDS2_PSEHT            Unreviewed;       315 AA.
AC   Q3IDS2;
DT   08-NOV-2005, integrated into UniProtKB/TrEMBL.
DT   08-NOV-2005, sequence version 1.
DT   08-MAY-2019, entry version 100.
DE   RecName: Full=Tyrosine recombinase XerC {ECO:0000256|HAMAP-Rule:MF_01808};
GN   Name=xerC {ECO:0000256|HAMAP-Rule:MF_01808,
GN   ECO:0000313|EMBL:CAI85199.1};
GN   OrderedLocusNames=PSHAa0090 {ECO:0000313|EMBL:CAI85199.1};
OS   Pseudoalteromonas haloplanktis (strain TAC 125).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC   Pseudoalteromonadaceae; Pseudoalteromonas.
OX   NCBI_TaxID=326442 {ECO:0000313|EMBL:CAI85199.1, ECO:0000313|Proteomes:UP000006843};
RN   [1] {ECO:0000313|EMBL:CAI85199.1, ECO:0000313|Proteomes:UP000006843}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TAC 125 {ECO:0000313|Proteomes:UP000006843};
RX   PubMed=16169927; DOI=10.1101/gr.4126905;
RA   Medigue C., Krin E., Pascal G., Barbe V., Bernsel A., Bertin P.,
RA   Cheung F., Cruveiller S., Damico S., Duilio A., Fang G., Feller G.,
RA   Mangenot S., Marino G., Nilsson J., Parilli E., Rocha E., Rouy Z.,
RA   Sekowska A., Tutino M.L., Vallenet D., von Heijne G., Danchin A.;
RT   "Coping with cold: the genome of the versatile marine Antarctica
RT   bacterium Pseudoalteromonas haloplanktis TAC125.";
RL   Genome Res. 15:1325-1335(2005).
CC   -!- FUNCTION: Site-specific tyrosine recombinase, which acts by
CC       catalyzing the cutting and rejoining of the recombining DNA
CC       molecules. The XerC-XerD complex is essential to convert dimers of
CC       the bacterial chromosome into monomers to permit their segregation
CC       at cell division. It also contributes to the segregational
CC       stability of plasmids. {ECO:0000256|HAMAP-Rule:MF_01808}.
CC   -!- SUBUNIT: Forms a cyclic heterotetrameric complex composed of two
CC       molecules of XerC and two molecules of XerD. {ECO:0000256|HAMAP-
CC       Rule:MF_01808, ECO:0000256|SAAS:SAAS00608017}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01808,
CC       ECO:0000256|SAAS:SAAS00019473}.
CC   -!- SIMILARITY: Belongs to the 'phage' integrase family. XerC
CC       subfamily. {ECO:0000256|HAMAP-Rule:MF_01808,
CC       ECO:0000256|SAAS:SAAS00608022}.
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DR   EMBL; CR954246; CAI85199.1; -; Genomic_DNA.
DR   RefSeq; WP_011326817.1; NC_007481.1.
DR   STRING; 326442.PSHAa0090; -.
DR   EnsemblBacteria; CAI85199; CAI85199; PSHAa0090.
DR   KEGG; pha:PSHAa0090; -.
DR   PATRIC; fig|326442.8.peg.89; -.
DR   eggNOG; ENOG4108IYS; Bacteria.
DR   eggNOG; COG4973; LUCA.
DR   HOGENOM; HOG000045294; -.
DR   KO; K03733; -.
DR   OMA; FASHMLE; -.
DR   OrthoDB; 745068at2; -.
DR   BioCyc; PHAL326442:PSHA_RS00460-MONOMER; -.
DR   Proteomes; UP000006843; Chromosome I.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0009037; F:tyrosine-based site-specific recombinase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006313; P:transposition, DNA-mediated; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.150.130; -; 1.
DR   Gene3D; 1.10.443.10; -; 1.
DR   HAMAP; MF_01808; Recomb_XerC_XerD; 1.
DR   InterPro; IPR011010; DNA_brk_join_enz.
DR   InterPro; IPR013762; Integrase-like_cat_sf.
DR   InterPro; IPR002104; Integrase_catalytic.
DR   InterPro; IPR010998; Integrase_recombinase_N.
DR   InterPro; IPR004107; Integrase_SAM-like_N.
DR   InterPro; IPR023009; Tyrosine_recombinase_XerC/XerD.
DR   Pfam; PF02899; Phage_int_SAM_1; 1.
DR   Pfam; PF00589; Phage_integrase; 1.
DR   SUPFAM; SSF56349; SSF56349; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q3IDS2.
DR   SWISS-2DPAGE; Q3IDS2.
KW   Cell cycle {ECO:0000256|HAMAP-Rule:MF_01808,
KW   ECO:0000256|SAAS:SAAS00608023};
KW   Cell division {ECO:0000256|HAMAP-Rule:MF_01808,
KW   ECO:0000256|SAAS:SAAS00608024};
KW   Chromosome partition {ECO:0000256|HAMAP-Rule:MF_01808,
KW   ECO:0000256|SAAS:SAAS00608018};
KW   Complete proteome {ECO:0000313|Proteomes:UP000006843};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01808,
KW   ECO:0000256|SAAS:SAAS00094312};
KW   DNA integration {ECO:0000256|HAMAP-Rule:MF_01808,
KW   ECO:0000256|SAAS:SAAS00298355};
KW   DNA recombination {ECO:0000256|HAMAP-Rule:MF_01808,
KW   ECO:0000256|SAAS:SAAS00019433};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_01808,
KW   ECO:0000256|SAAS:SAAS00424103};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006843}.
FT   DOMAIN       21    101       Integrase_SAM-like_N. {ECO:0000259|Pfam:
FT                                PF02899}.
FT   DOMAIN      128    296       Phage_integrase. {ECO:0000259|Pfam:
FT                                PF00589}.
FT   ACT_SITE    163    163       {ECO:0000256|HAMAP-Rule:MF_01808}.
FT   ACT_SITE    187    187       {ECO:0000256|HAMAP-Rule:MF_01808}.
FT   ACT_SITE    256    256       {ECO:0000256|HAMAP-Rule:MF_01808}.
FT   ACT_SITE    259    259       {ECO:0000256|HAMAP-Rule:MF_01808}.
FT   ACT_SITE    282    282       {ECO:0000256|HAMAP-Rule:MF_01808}.
FT   ACT_SITE    291    291       O-(3'-phospho-DNA)-tyrosine intermediate.
FT                                {ECO:0000256|HAMAP-Rule:MF_01808}.
SQ   SEQUENCE   315 AA;  35732 MW;  8A81B77886510C47 CRC64;
     MSDNPAPNIS DLSDNWRTPI TLFSDYLKFE RQYSAHTVNQ YVSQLGFAAL YFSKLCDDWF
     SVQGEHIRRY SMALRSKQLS GRTISLKLSC IRSLYKFLKA KNIAKQAHYH NPAVGIKGPK
     FAKPLPKNLD VDQMARLLEI PDDEPLAIRD KAMMELMYSS GLRISELVGA NLQDISAANG
     EILVRGKGNK ERLIPVGSKA LNALKKWLII RPQFANPDEV AVFLSSKKNR ISVRQVRLRM
     QEWGIKQGIS SQVHPHKLRH SFASHILESS GDLRAVQELL GHSSLSATQV YTHLDFQHLA
     KVYDNTHPRA KKRTD
//

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