(data stored in SCRATCH zone)

SWISSPROT: Q3IIB4_PSEHT

ID   Q3IIB4_PSEHT            Unreviewed;       651 AA.
AC   Q3IIB4;
DT   08-NOV-2005, integrated into UniProtKB/TrEMBL.
DT   08-NOV-2005, sequence version 1.
DT   07-JUN-2017, entry version 93.
DE   RecName: Full=Signal recognition particle receptor FtsY {ECO:0000256|HAMAP-Rule:MF_00920};
DE            Short=SRP receptor {ECO:0000256|HAMAP-Rule:MF_00920};
GN   Name=ftsY {ECO:0000256|HAMAP-Rule:MF_00920,
GN   ECO:0000313|EMBL:CAI85452.1};
GN   OrderedLocusNames=PSHAa0354 {ECO:0000313|EMBL:CAI85452.1};
OS   Pseudoalteromonas haloplanktis (strain TAC 125).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC   Pseudoalteromonadaceae; Pseudoalteromonas.
OX   NCBI_TaxID=326442 {ECO:0000313|EMBL:CAI85452.1, ECO:0000313|Proteomes:UP000006843};
RN   [1] {ECO:0000313|EMBL:CAI85452.1, ECO:0000313|Proteomes:UP000006843}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TAC 125 {ECO:0000313|Proteomes:UP000006843};
RX   PubMed=16169927; DOI=10.1101/gr.4126905;
RA   Medigue C., Krin E., Pascal G., Barbe V., Bernsel A., Bertin P.,
RA   Cheung F., Cruveiller S., Damico S., Duilio A., Fang G., Feller G.,
RA   Mangenot S., Marino G., Nilsson J., Parilli E., Rocha E., Rouy Z.,
RA   Sekowska A., Tutino M.L., Vallenet D., von Heijne G., Danchin A.;
RT   "Coping with cold: the genome of the versatile marine Antarctica
RT   bacterium Pseudoalteromonas haloplanktis TAC125.";
RL   Genome Res. 15:1325-1335(2005).
CC   -!- FUNCTION: Involved in targeting and insertion of nascent membrane
CC       proteins into the cytoplasmic membrane. Acts as a receptor for the
CC       complex formed by the signal recognition particle (SRP) and the
CC       ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to
CC       the transfer of the RNC complex to the Sec translocase for
CC       insertion into the membrane, the hydrolysis of GTP by both Ffh and
CC       FtsY, and the dissociation of the SRP-FtsY complex into the
CC       individual components. {ECO:0000256|HAMAP-Rule:MF_00920}.
CC   -!- SUBUNIT: Part of the signal recognition particle protein
CC       translocation system, which is composed of SRP and FtsY. SRP is a
CC       ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.
CC       {ECO:0000256|HAMAP-Rule:MF_00920}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000256|HAMAP-
CC       Rule:MF_00920}; Peripheral membrane protein {ECO:0000256|HAMAP-
CC       Rule:MF_00920}; Cytoplasmic side {ECO:0000256|HAMAP-
CC       Rule:MF_00920}. Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00920}.
CC   -!- SIMILARITY: Belongs to the GTP-binding SRP family. FtsY subfamily.
CC       {ECO:0000256|HAMAP-Rule:MF_00920}.
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DR   EMBL; CR954246; CAI85452.1; -; Genomic_DNA.
DR   ProteinModelPortal; Q3IIB4; -.
DR   STRING; 326442.PSHAa0354; -.
DR   EnsemblBacteria; CAI85452; CAI85452; PSHAa0354.
DR   KEGG; pha:PSHAa0354; -.
DR   eggNOG; ENOG4105CCP; Bacteria.
DR   eggNOG; COG0552; LUCA.
DR   HOGENOM; HOG000036278; -.
DR   KO; K03110; -.
DR   OMA; FTWSAMV; -.
DR   OrthoDB; POG091H021F; -.
DR   Proteomes; UP000006843; Chromosome I.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0031226; C:intrinsic component of plasma membrane; IEA:UniProtKB-HAMAP.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003924; F:GTPase activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; IEA:InterPro.
DR   HAMAP; MF_00920; FtsY; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR013822; Signal_recog_particl_SRP54_hlx.
DR   InterPro; IPR004390; SR_rcpt_FtsY.
DR   InterPro; IPR000897; SRP54_GTPase_dom.
DR   PANTHER; PTHR43134:SF1; PTHR43134:SF1; 1.
DR   Pfam; PF00448; SRP54; 1.
DR   Pfam; PF02881; SRP54_N; 1.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00962; SRP54; 1.
DR   SMART; SM00963; SRP54_N; 1.
DR   SUPFAM; SSF47364; SSF47364; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00064; ftsY; 1.
DR   PROSITE; PS00300; SRP54; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q3IIB4.
DR   SWISS-2DPAGE; Q3IIB4.
KW   Cell cycle {ECO:0000313|EMBL:CAI85452.1};
KW   Cell division {ECO:0000313|EMBL:CAI85452.1};
KW   Cell inner membrane {ECO:0000256|HAMAP-Rule:MF_00920};
KW   Cell membrane {ECO:0000256|HAMAP-Rule:MF_00920};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000006843};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00920};
KW   GTP-binding {ECO:0000256|HAMAP-Rule:MF_00920};
KW   Membrane {ECO:0000256|HAMAP-Rule:MF_00920};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00920};
KW   Receptor {ECO:0000256|HAMAP-Rule:MF_00920};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006843}.
FT   DOMAIN      618    631       SRP54. {ECO:0000259|PROSITE:PS00300}.
FT   NP_BIND     451    458       GTP. {ECO:0000256|HAMAP-Rule:MF_00920}.
FT   NP_BIND     533    537       GTP. {ECO:0000256|HAMAP-Rule:MF_00920}.
FT   NP_BIND     597    600       GTP. {ECO:0000256|HAMAP-Rule:MF_00920}.
FT   COILED       15    332       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   651 AA;  71914 MW;  9685194ADD0851B4 CRC64;
     MAKKSKLLSW LGFGKSDKKQ QAEQSAQEAD NQQQARLAAE KAEAEHLEQQ RLAAEKAEQE
     AAEKIAAEQA QREQAEKLAI EKANAELLAK QQADAHALQL EQQQRLAEQE AQMRLEQEKA
     AAEQAEAERL EQARIVAEQA EAENLEQRKL AAEQAQREQA EKLAIEKANA ELLAKQQADA
     HALQLEQQQR LAEQEAQIRL DQEKAAAEKA EAERLEQTRI AAEQAEAERL EQTRIAAEQA
     EAERLEQARI AAEQAEAERA EAERAEAERA EAERLEQVRI AAEQAEAEQL EQQRIADEQA
     EAERLEQQRI AAEQAEAEHL EQQRIADELA SEAAQKVEKP KKEGFFSRLK KGLLKTRVNI
     GSGFASIFSG KKIDDDLFEE LETQLLTADL GVDTTMKLID RLTDAANRKQ LKDGDALYEL
     MKQEMAVMLK TAEQPLVIPA DKKPFVILMV GVNGVGKTTT IGKLAKQFQS EGKSVMLAAG
     DTFRAAAVEQ LQVWGERNSI PVIAQHTGAD SASVIFDAFQ AAKARNVDVL IADTAGRLQN
     KDNLMQELEK IARVMKKIDP DAPHEVMLTI DAGTGQNAIS QVNLFNQCVG LTGITLSKLD
     GTAKGGVIFA VADKFNIPIR YIGVGESIDD LRAFKSDDFI DALFSQDEDD A
//

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