(data stored in SCRATCH zone)

SWISSPROT: Q3ILE1_PSEHT

ID   Q3ILE1_PSEHT            Unreviewed;       308 AA.
AC   Q3ILE1;
DT   08-NOV-2005, integrated into UniProtKB/TrEMBL.
DT   08-NOV-2005, sequence version 1.
DT   08-MAY-2019, entry version 110.
DE   RecName: Full=Tyrosine recombinase XerD {ECO:0000256|HAMAP-Rule:MF_01807};
GN   Name=xerD {ECO:0000256|HAMAP-Rule:MF_01807,
GN   ECO:0000313|EMBL:CAI85604.1};
GN   OrderedLocusNames=PSHAa0514 {ECO:0000313|EMBL:CAI85604.1};
OS   Pseudoalteromonas haloplanktis (strain TAC 125).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC   Pseudoalteromonadaceae; Pseudoalteromonas.
OX   NCBI_TaxID=326442 {ECO:0000313|EMBL:CAI85604.1, ECO:0000313|Proteomes:UP000006843};
RN   [1] {ECO:0000313|EMBL:CAI85604.1, ECO:0000313|Proteomes:UP000006843}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TAC 125 {ECO:0000313|Proteomes:UP000006843};
RX   PubMed=16169927; DOI=10.1101/gr.4126905;
RA   Medigue C., Krin E., Pascal G., Barbe V., Bernsel A., Bertin P.,
RA   Cheung F., Cruveiller S., Damico S., Duilio A., Fang G., Feller G.,
RA   Mangenot S., Marino G., Nilsson J., Parilli E., Rocha E., Rouy Z.,
RA   Sekowska A., Tutino M.L., Vallenet D., von Heijne G., Danchin A.;
RT   "Coping with cold: the genome of the versatile marine Antarctica
RT   bacterium Pseudoalteromonas haloplanktis TAC125.";
RL   Genome Res. 15:1325-1335(2005).
CC   -!- FUNCTION: Site-specific tyrosine recombinase, which acts by
CC       catalyzing the cutting and rejoining of the recombining DNA
CC       molecules. The XerC-XerD complex is essential to convert dimers of
CC       the bacterial chromosome into monomers to permit their segregation
CC       at cell division. It also contributes to the segregational
CC       stability of plasmids. {ECO:0000256|HAMAP-Rule:MF_01807}.
CC   -!- SUBUNIT: Forms a cyclic heterotetrameric complex composed of two
CC       molecules of XerC and two molecules of XerD. {ECO:0000256|HAMAP-
CC       Rule:MF_01807, ECO:0000256|SAAS:SAAS00608017}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01807,
CC       ECO:0000256|SAAS:SAAS00019473}.
CC   -!- SIMILARITY: Belongs to the 'phage' integrase family. XerD
CC       subfamily. {ECO:0000256|HAMAP-Rule:MF_01807}.
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DR   EMBL; CR954246; CAI85604.1; -; Genomic_DNA.
DR   RefSeq; WP_011327217.1; NC_007481.1.
DR   STRING; 326442.PSHAa0514; -.
DR   EnsemblBacteria; CAI85604; CAI85604; PSHAa0514.
DR   KEGG; pha:PSHAa0514; -.
DR   PATRIC; fig|326442.8.peg.483; -.
DR   eggNOG; ENOG4105C13; Bacteria.
DR   eggNOG; COG4974; LUCA.
DR   HOGENOM; HOG000045296; -.
DR   KO; K04763; -.
DR   OMA; AFWYLIK; -.
DR   OrthoDB; 745068at2; -.
DR   BioCyc; PHAL326442:PSHA_RS02490-MONOMER; -.
DR   Proteomes; UP000006843; Chromosome I.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0009037; F:tyrosine-based site-specific recombinase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006313; P:transposition, DNA-mediated; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.150.130; -; 1.
DR   Gene3D; 1.10.443.10; -; 1.
DR   HAMAP; MF_01808; Recomb_XerC_XerD; 1.
DR   HAMAP; MF_01807; Recomb_XerD; 1.
DR   InterPro; IPR011010; DNA_brk_join_enz.
DR   InterPro; IPR013762; Integrase-like_cat_sf.
DR   InterPro; IPR002104; Integrase_catalytic.
DR   InterPro; IPR010998; Integrase_recombinase_N.
DR   InterPro; IPR004107; Integrase_SAM-like_N.
DR   InterPro; IPR011932; Recomb_XerD.
DR   InterPro; IPR023009; Tyrosine_recombinase_XerC/XerD.
DR   Pfam; PF02899; Phage_int_SAM_1; 1.
DR   Pfam; PF00589; Phage_integrase; 1.
DR   SUPFAM; SSF56349; SSF56349; 1.
DR   TIGRFAMs; TIGR02225; recomb_XerD; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q3ILE1.
DR   SWISS-2DPAGE; Q3ILE1.
KW   Cell cycle {ECO:0000256|HAMAP-Rule:MF_01807,
KW   ECO:0000256|SAAS:SAAS00608023};
KW   Cell division {ECO:0000256|HAMAP-Rule:MF_01807,
KW   ECO:0000256|SAAS:SAAS00608024};
KW   Chromosome partition {ECO:0000256|HAMAP-Rule:MF_01807,
KW   ECO:0000256|SAAS:SAAS00608018};
KW   Complete proteome {ECO:0000313|Proteomes:UP000006843};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01807,
KW   ECO:0000256|SAAS:SAAS00094312};
KW   DNA integration {ECO:0000256|HAMAP-Rule:MF_01807,
KW   ECO:0000256|SAAS:SAAS00298355};
KW   DNA recombination {ECO:0000256|HAMAP-Rule:MF_01807,
KW   ECO:0000256|SAAS:SAAS00019433};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_01807,
KW   ECO:0000256|SAAS:SAAS00424103};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006843}.
FT   DOMAIN       22    102       Integrase_SAM-like_N. {ECO:0000259|Pfam:
FT                                PF02899}.
FT   DOMAIN      124    294       Phage_integrase. {ECO:0000259|Pfam:
FT                                PF00589}.
FT   ACT_SITE    160    160       {ECO:0000256|HAMAP-Rule:MF_01807}.
FT   ACT_SITE    184    184       {ECO:0000256|HAMAP-Rule:MF_01807}.
FT   ACT_SITE    254    254       {ECO:0000256|HAMAP-Rule:MF_01807}.
FT   ACT_SITE    257    257       {ECO:0000256|HAMAP-Rule:MF_01807}.
FT   ACT_SITE    280    280       {ECO:0000256|HAMAP-Rule:MF_01807}.
FT   ACT_SITE    289    289       O-(3'-phospho-DNA)-tyrosine intermediate.
FT                                {ECO:0000256|HAMAP-Rule:MF_01807}.
SQ   SEQUENCE   308 AA;  34742 MW;  6D25100705F4AF7E CRC64;
     MTTLADDFSE PSTAPKSNND YLETFLDCLY LEQGVSENTL SAYRSDLDKF CQFLKGKNLM
     TVTGLDVESY LAHRVDLGLK PRSTARSISA LKRFYQYFVR EKLISDSPML NIAQPKAGQS
     LPKTLSEAEV EALLSAPNTD EPMGLRDKAM LELLYATGLR VSELVGLRIE QINLRQAVVF
     VKGKGNKERL VPLGEEAMYW LEQFLKVGRA QMIKHATDFV FPSKRGVGMT RQTFWHRVKH
     YAILASIESS LSPHTLRHAF ATHLLNHGAD LRVVQMMLGH SDLSTTQIYT HVANERLKSV
     HAQHHPRA
//

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