(data stored in SCRATCH zone)

SWISSPROT: Q3KJH3_PSEPF

ID   Q3KJH3_PSEPF            Unreviewed;       478 AA.
AC   Q3KJH3;
DT   08-NOV-2005, integrated into UniProtKB/TrEMBL.
DT   08-NOV-2005, sequence version 1.
DT   08-MAY-2019, entry version 127.
DE   RecName: Full=DNA-binding transcriptional regulator NtrC {ECO:0000256|RuleBase:RU365013};
DE   AltName: Full=Nitrogen regulation protein NR(I) {ECO:0000256|RuleBase:RU365013};
GN   Name=ntrC {ECO:0000256|RuleBase:RU365013};
GN   OrderedLocusNames=Pfl01_0339 {ECO:0000313|EMBL:ABA72083.1};
OS   Pseudomonas fluorescens (strain Pf0-1).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=205922 {ECO:0000313|EMBL:ABA72083.1, ECO:0000313|Proteomes:UP000002704};
RN   [1] {ECO:0000313|EMBL:ABA72083.1, ECO:0000313|Proteomes:UP000002704}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Pf0-1 {ECO:0000313|EMBL:ABA72083.1,
RC   ECO:0000313|Proteomes:UP000002704};
RX   PubMed=19432983; DOI=10.1186/gb-2009-10-5-r51;
RA   Silby M.W., Cerdeno-Tarraga A.M., Vernikos G.S., Giddens S.R.,
RA   Jackson R.W., Preston G.M., Zhang X.X., Moon C.D., Gehrig S.M.,
RA   Godfrey S.A., Knight C.G., Malone J.G., Robinson Z., Spiers A.J.,
RA   Harris S., Challis G.L., Yaxley A.M., Harris D., Seeger K., Murphy L.,
RA   Rutter S., Squares R., Quail M.A., Saunders E., Mavromatis K.,
RA   Brettin T.S., Bentley S.D., Hothersall J., Stephens E., Thomas C.M.,
RA   Parkhill J., Levy S.B., Rainey P.B., Thomson N.R.;
RT   "Genomic and genetic analyses of diversity and plant interactions of
RT   Pseudomonas fluorescens.";
RL   Genome Biol. 10:R51.1-R51.16(2009).
CC   -!- FUNCTION: Member of the two-component regulatory system NtrB/NtrC,
CC       which controls expression of the nitrogen-regulated (ntr) genes in
CC       response to nitrogen limitation. Phosphorylated NtrC binds
CC       directly to DNA and stimulates the formation of open promoter-
CC       sigma54-RNA polymerase complexes. {ECO:0000256|RuleBase:RU365013}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|RuleBase:RU365013}.
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DR   EMBL; CP000094; ABA72083.1; -; Genomic_DNA.
DR   RefSeq; WP_011332028.1; NC_007492.2.
DR   STRING; 205922.Pfl01_0339; -.
DR   PRIDE; Q3KJH3; -.
DR   EnsemblBacteria; ABA72083; ABA72083; Pfl01_0339.
DR   KEGG; pfo:Pfl01_0339; -.
DR   eggNOG; ENOG4105C1W; Bacteria.
DR   eggNOG; COG2204; LUCA.
DR   HOGENOM; HOG000058489; -.
DR   KO; K07712; -.
DR   OMA; DWTGNIR; -.
DR   BioCyc; PFLU205922:G1G4S-343-MONOMER; -.
DR   Proteomes; UP000002704; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0000156; F:phosphorelay response regulator activity; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0008134; F:transcription factor binding; IEA:InterPro.
DR   GO; GO:0009399; P:nitrogen fixation; IEA:UniProtKB-KW.
DR   GO; GO:0006808; P:regulation of nitrogen utilization; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   CDD; cd00156; REC; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR011006; CheY-like_superfamily.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR002197; HTH_Fis.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR   InterPro; IPR002078; Sigma_54_int.
DR   InterPro; IPR025662; Sigma_54_int_dom_ATP-bd_1.
DR   InterPro; IPR025943; Sigma_54_int_dom_ATP-bd_2.
DR   InterPro; IPR025944; Sigma_54_int_dom_CS.
DR   InterPro; IPR010114; Trancript_reg_NtrC.
DR   Pfam; PF02954; HTH_8; 1.
DR   Pfam; PF00072; Response_reg; 1.
DR   Pfam; PF00158; Sigma54_activat; 1.
DR   PRINTS; PR01590; HTHFIS.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00448; REC; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   SUPFAM; SSF52172; SSF52172; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR01818; ntrC; 1.
DR   PROSITE; PS50110; RESPONSE_REGULATORY; 1.
DR   PROSITE; PS00675; SIGMA54_INTERACT_1; 1.
DR   PROSITE; PS00676; SIGMA54_INTERACT_2; 1.
DR   PROSITE; PS00688; SIGMA54_INTERACT_3; 1.
DR   PROSITE; PS50045; SIGMA54_INTERACT_4; 1.
PE   4: Predicted;
DR   PRODOM; Q3KJH3.
DR   SWISS-2DPAGE; Q3KJH3.
KW   Activator {ECO:0000256|RuleBase:RU365013};
KW   ATP-binding {ECO:0000256|RuleBase:RU365013,
KW   ECO:0000256|SAAS:SAAS00473007};
KW   Complete proteome {ECO:0000313|Proteomes:UP000002704};
KW   Cytoplasm {ECO:0000256|RuleBase:RU365013};
KW   DNA-binding {ECO:0000256|RuleBase:RU365013,
KW   ECO:0000256|SAAS:SAAS00421512};
KW   Nitrogen fixation {ECO:0000256|RuleBase:RU365013};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU365013,
KW   ECO:0000256|SAAS:SAAS00473126};
KW   Phosphoprotein {ECO:0000256|PROSITE-ProRule:PRU00169};
KW   Repressor {ECO:0000256|RuleBase:RU365013};
KW   Transcription {ECO:0000256|RuleBase:RU365013,
KW   ECO:0000256|SAAS:SAAS00814760};
KW   Transcription regulation {ECO:0000256|RuleBase:RU365013,
KW   ECO:0000256|SAAS:SAAS00814754};
KW   Two-component regulatory system {ECO:0000256|RuleBase:RU365013}.
FT   DOMAIN        6    120       Response regulatory.
FT                                {ECO:0000259|PROSITE:PS50110}.
FT   DOMAIN      141    370       Sigma-54 factor interaction.
FT                                {ECO:0000259|PROSITE:PS50045}.
FT   MOD_RES      55     55       4-aspartylphosphate.
FT                                {ECO:0000256|PROSITE-ProRule:PRU00169}.
SQ   SEQUENCE   478 AA;  53041 MW;  B763315B0A0F3364 CRC64;
     MSRSETVWIV DDDRSIRWVL EKALQQEGMT TQSFDSADGV MSRLARQQPD VIISDIRMPG
     ASGLDLLARI REQHPRLPVI IMTAHSDLDS AVASYQGGAF EYLPKPFDVD EAVSLVKRAN
     QHAQEQQGLE VAPALTRTPE IIGEAPAMQE VFRAIGRLSH SNITVLINGE SGTGKELVAH
     ALHRHSPRAA SPFIALNMAA IPKDLMESEL FGHEKGAFTG AANLRRGRFE QADGGTLFLD
     EIGDMPADTQ TRLLRVLADG EFYRVGGHVP VKVDVRIIAA THQNLETLVH AGKFREDLFH
     RLNVIRIHIP RLSDRREDIP TLAKHFLSRA AQELAVEPKL LKSETEEYLK NLPWPGNVRQ
     LENTCRWITV MASGREVHIS DLPPELLSLP QDSAPVTNWE QALRQWADQA LARGQSSLLD
     SAVPAFERIM IETALKHTAG RRRDAAVLLG WGRNTLTRKI KELGMKVDGG DDDEGDEG
//

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