(data stored in SCRATCH zone)

SWISSPROT: Q3KK84_PSEPF

ID   Q3KK84_PSEPF            Unreviewed;       530 AA.
AC   Q3KK84;
DT   08-NOV-2005, integrated into UniProtKB/TrEMBL.
DT   08-NOV-2005, sequence version 1.
DT   08-MAY-2019, entry version 109.
DE   RecName: Full=Cytochrome c oxidase subunit 1 {ECO:0000256|RuleBase:RU363061};
DE            EC=1.9.3.1 {ECO:0000256|RuleBase:RU363061};
GN   OrderedLocusNames=Pfl01_0078 {ECO:0000313|EMBL:ABA71822.1};
OS   Pseudomonas fluorescens (strain Pf0-1).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=205922 {ECO:0000313|EMBL:ABA71822.1, ECO:0000313|Proteomes:UP000002704};
RN   [1] {ECO:0000313|EMBL:ABA71822.1, ECO:0000313|Proteomes:UP000002704}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Pf0-1 {ECO:0000313|EMBL:ABA71822.1,
RC   ECO:0000313|Proteomes:UP000002704};
RX   PubMed=19432983; DOI=10.1186/gb-2009-10-5-r51;
RA   Silby M.W., Cerdeno-Tarraga A.M., Vernikos G.S., Giddens S.R.,
RA   Jackson R.W., Preston G.M., Zhang X.X., Moon C.D., Gehrig S.M.,
RA   Godfrey S.A., Knight C.G., Malone J.G., Robinson Z., Spiers A.J.,
RA   Harris S., Challis G.L., Yaxley A.M., Harris D., Seeger K., Murphy L.,
RA   Rutter S., Squares R., Quail M.A., Saunders E., Mavromatis K.,
RA   Brettin T.S., Bentley S.D., Hothersall J., Stephens E., Thomas C.M.,
RA   Parkhill J., Levy S.B., Rainey P.B., Thomson N.R.;
RT   "Genomic and genetic analyses of diversity and plant interactions of
RT   Pseudomonas fluorescens.";
RL   Genome Biol. 10:R51.1-R51.16(2009).
CC   -!- FUNCTION: Cytochrome c oxidase is the component of the respiratory
CC       chain that catalyzes the reduction of oxygen to water. Subunits 1-
CC       3 form the functional core of the enzyme complex. CO I is the
CC       catalytic subunit of the enzyme. Electrons originating in
CC       cytochrome c are transferred via the copper A center of subunit 2
CC       and heme A of subunit 1 to the bimetallic center formed by heme A3
CC       and copper B. {ECO:0000256|RuleBase:RU363061}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=4 [Fe(II)cytochrome c] + 4 H(+) + O2 = 4
CC         [Fe(III)cytochrome c] + 2 H2O; Xref=Rhea:RHEA:11436, Rhea:RHEA-
CC         COMP:10350, Rhea:RHEA-COMP:14399, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:15379, ChEBI:CHEBI:29033,
CC         ChEBI:CHEBI:29034; EC=1.9.3.1;
CC         Evidence={ECO:0000256|RuleBase:RU363061};
CC   -!- PATHWAY: Energy metabolism; oxidative phosphorylation.
CC       {ECO:0000256|RuleBase:RU363061}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane
CC       {ECO:0000256|RuleBase:RU363061}; Multi-pass membrane protein
CC       {ECO:0000256|RuleBase:RU363061}.
CC   -!- SIMILARITY: Belongs to the heme-copper respiratory oxidase family.
CC       {ECO:0000256|RuleBase:RU363061}.
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DR   EMBL; CP000094; ABA71822.1; -; Genomic_DNA.
DR   RefSeq; WP_011331800.1; NC_007492.2.
DR   STRING; 205922.Pfl01_0078; -.
DR   EnsemblBacteria; ABA71822; ABA71822; Pfl01_0078.
DR   KEGG; pfo:Pfl01_0078; -.
DR   eggNOG; ENOG4105BZ9; Bacteria.
DR   eggNOG; COG0843; LUCA.
DR   HOGENOM; HOG000085274; -.
DR   KO; K02274; -.
DR   OMA; PVDFQYH; -.
DR   BioCyc; PFLU205922:G1G4S-78-MONOMER; -.
DR   UniPathway; UPA00705; -.
DR   Proteomes; UP000002704; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0045277; C:respiratory chain complex IV; IEA:InterPro.
DR   GO; GO:0004129; F:cytochrome-c oxidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0009060; P:aerobic respiration; IEA:InterPro.
DR   GO; GO:0015990; P:electron transport coupled proton transport; IEA:InterPro.
DR   GO; GO:0006119; P:oxidative phosphorylation; IEA:UniProtKB-UniPathway.
DR   CDD; cd01663; Cyt_c_Oxidase_I; 1.
DR   Gene3D; 1.20.210.10; -; 1.
DR   InterPro; IPR023616; Cyt_c_oxase-like_su1_dom.
DR   InterPro; IPR036927; Cyt_c_oxase-like_su1_sf.
DR   InterPro; IPR000883; Cyt_C_Oxase_1.
DR   InterPro; IPR023615; Cyt_c_Oxase_su1_BS.
DR   InterPro; IPR033944; Cyt_c_oxase_su1_dom.
DR   InterPro; IPR014241; Cyt_c_oxidase_su1_bac.
DR   PANTHER; PTHR10422; PTHR10422; 1.
DR   Pfam; PF00115; COX1; 1.
DR   PRINTS; PR01165; CYCOXIDASEI.
DR   SUPFAM; SSF81442; SSF81442; 1.
DR   TIGRFAMs; TIGR02891; CtaD_CoxA; 1.
DR   PROSITE; PS50855; COX1; 1.
DR   PROSITE; PS00077; COX1_CUB; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q3KK84.
DR   SWISS-2DPAGE; Q3KK84.
KW   Cell membrane {ECO:0000256|RuleBase:RU363061};
KW   Complete proteome {ECO:0000313|Proteomes:UP000002704};
KW   Copper {ECO:0000256|RuleBase:RU363061};
KW   Electron transport {ECO:0000256|RuleBase:RU363061};
KW   Heme {ECO:0000256|RuleBase:RU363061};
KW   Iron {ECO:0000256|RuleBase:RU363061};
KW   Membrane {ECO:0000256|RuleBase:RU363061};
KW   Metal-binding {ECO:0000256|RuleBase:RU363061};
KW   Oxidoreductase {ECO:0000256|RuleBase:RU363061};
KW   Respiratory chain {ECO:0000256|RuleBase:RU363061};
KW   Transmembrane {ECO:0000256|RuleBase:RU363061};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU363061};
KW   Transport {ECO:0000256|RuleBase:RU363061}.
FT   TRANSMEM     38     59       Helical. {ECO:0000256|RuleBase:RU363061}.
FT   TRANSMEM     79    100       Helical. {ECO:0000256|RuleBase:RU363061}.
FT   TRANSMEM    121    141       Helical. {ECO:0000256|RuleBase:RU363061}.
FT   TRANSMEM    161    189       Helical. {ECO:0000256|RuleBase:RU363061}.
FT   TRANSMEM    201    228       Helical. {ECO:0000256|RuleBase:RU363061}.
FT   TRANSMEM    248    272       Helical. {ECO:0000256|RuleBase:RU363061}.
FT   TRANSMEM    284    306       Helical. {ECO:0000256|RuleBase:RU363061}.
FT   TRANSMEM    312    335       Helical. {ECO:0000256|RuleBase:RU363061}.
FT   TRANSMEM    356    378       Helical. {ECO:0000256|RuleBase:RU363061}.
FT   TRANSMEM    390    414       Helical. {ECO:0000256|RuleBase:RU363061}.
FT   TRANSMEM    426    447       Helical. {ECO:0000256|RuleBase:RU363061}.
FT   TRANSMEM    467    490       Helical. {ECO:0000256|RuleBase:RU363061}.
FT   DOMAIN       26    530       COX1. {ECO:0000259|PROSITE:PS50855}.
SQ   SEQUENCE   530 AA;  58850 MW;  1E22B5C759F879C7 CRC64;
     MSAVIDDHGH ADHDHAHGPA KGLMRWVLTT NHKDIGTLYL WFAFCMFLLG GSFAMVIRAE
     LFQPGLQIVE PAFFNQMTTM HGLVMVFGAV MPAFVGLANW MIPLMVGAPD MALPRMNNFS
     FWLLPAAFLL LVSTLFTAGG GPNFGWTFYA PLSTTYAPES VTFFIFAIHL MGISSIMGAI
     NVIATILNLR APGMTLMKMP LFVWTWLITA FLLIAVMPVL AGCVTMMLMD IHFGTSFFSA
     AGGGDPVLFQ HVFWFFGHPE VYIMILPAFG AVSQIIPTFS RKPLFGYTSM VYATASIAFL
     SFIVWAHHMF VVGIPLVGEL FFMYATMLIA VPTGVKVFNW ASTMWQGSMT FETPMLFAVA
     FVILFSIGGF SGLMLAIAPA DFQYQDTYFV VAHFHYVLVP GAIFGIFASA YYWLPKWTGH
     MYDETLGKLH FWLSFVGMNL TFFPMHFVGL AGMPRRIPDY NLQFADFNMV SSIGAFMFGA
     TQIFFLFIVI KTIRGGEPAP AKPWDGAEGL EWSVPSPAPY HTFTTPPEVK
//

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