SWISSPROT: Q3Z4M2_SHISS

ID   Q3Z4M2_SHISS            Unreviewed;       482 AA.
AC   Q3Z4M2;
DT   27-SEP-2005, integrated into UniProtKB/TrEMBL.
DT   27-SEP-2005, sequence version 1.
DT   08-MAY-2019, entry version 104.
DE   RecName: Full=Sensor protein {ECO:0000256|RuleBase:RU364088};
DE            EC=2.7.13.3 {ECO:0000256|RuleBase:RU364088};
GN   Name=ybcZ {ECO:0000313|EMBL:AAZ87290.1};
GN   OrderedLocusNames=SSON_0521 {ECO:0000313|EMBL:AAZ87290.1};
OS   Shigella sonnei (strain Ss046).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=300269 {ECO:0000313|EMBL:AAZ87290.1, ECO:0000313|Proteomes:UP000002529};
RN   [1] {ECO:0000313|EMBL:AAZ87290.1, ECO:0000313|Proteomes:UP000002529}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ss046 {ECO:0000313|EMBL:AAZ87290.1,
RC   ECO:0000313|Proteomes:UP000002529};
RX   PubMed=16275786; DOI=10.1093/nar/gki954;
RA   Yang F., Yang J., Zhang X., Chen L., Jiang Y., Yan Y., Tang X.,
RA   Wang J., Xiong Z., Dong J., Xue Y., Zhu Y., Xu X., Sun L., Chen S.,
RA   Nie H., Peng J., Xu J., Wang Y., Yuan Z., Wen Y., Yao Z., Shen Y.,
RA   Qiang B., Hou Y., Yu J., Jin Q.;
RT   "Genome dynamics and diversity of Shigella species, the etiologic
RT   agents of bacillary dysentery.";
RL   Nucleic Acids Res. 33:6445-6458(2005).
CC   -!- FUNCTION: Member of a two-component regulatory system.
CC       {ECO:0000256|RuleBase:RU364088}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC         histidine.; EC=2.7.13.3;
CC         Evidence={ECO:0000256|RuleBase:RU364088,
CC         ECO:0000256|SAAS:SAAS01126420};
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane
CC       {ECO:0000256|RuleBase:RU364088}.
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DR   EMBL; CP000038; AAZ87290.1; -; Genomic_DNA.
DR   EnsemblBacteria; AAZ87290; AAZ87290; SSON_0521.
DR   KEGG; ssn:SSON_0521; -.
DR   HOGENOM; HOG000126763; -.
DR   KO; K07644; -.
DR   OMA; ITETAQF; -.
DR   BioCyc; SSON300269:G1GL2-611-MONOMER; -.
DR   Proteomes; UP000002529; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR   CDD; cd06225; HAMP; 1.
DR   CDD; cd00075; HATPase_c; 1.
DR   CDD; cd00082; HisKA; 1.
DR   Gene3D; 3.30.565.10; -; 1.
DR   InterPro; IPR006290; CztS_silS_copS.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR005467; His_kinase_dom.
DR   InterPro; IPR003661; HisK_dim/P.
DR   InterPro; IPR036097; HisK_dim/P_sf.
DR   InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF02518; HATPase_c; 1.
DR   Pfam; PF00512; HisKA; 1.
DR   PRINTS; PR00344; BCTRLSENSOR.
DR   SMART; SM00304; HAMP; 1.
DR   SMART; SM00387; HATPase_c; 1.
DR   SMART; SM00388; HisKA; 1.
DR   SUPFAM; SSF47384; SSF47384; 1.
DR   SUPFAM; SSF55874; SSF55874; 1.
DR   TIGRFAMs; TIGR01386; cztS_silS_copS; 1.
DR   PROSITE; PS50885; HAMP; 1.
DR   PROSITE; PS50109; HIS_KIN; 1.
PE   4: Predicted;
DR   PRODOM; Q3Z4M2.
DR   SWISS-2DPAGE; Q3Z4M2.
KW   ATP-binding {ECO:0000256|RuleBase:RU364088,
KW   ECO:0000256|SAAS:SAAS00925949};
KW   Cell inner membrane {ECO:0000256|RuleBase:RU364088};
KW   Cell membrane {ECO:0000256|RuleBase:RU364088};
KW   Complete proteome {ECO:0000313|Proteomes:UP000002529};
KW   Kinase {ECO:0000256|RuleBase:RU364088, ECO:0000256|SAAS:SAAS01003914};
KW   Membrane {ECO:0000256|RuleBase:RU364088,
KW   ECO:0000256|SAAS:SAAS00925724};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU364088,
KW   ECO:0000256|SAAS:SAAS00925310};
KW   Transferase {ECO:0000256|RuleBase:RU364088,
KW   ECO:0000256|SAAS:SAAS01003669};
KW   Transmembrane {ECO:0000256|RuleBase:RU364088,
KW   ECO:0000256|SAAS:SAAS00926038};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU364088,
KW   ECO:0000256|SAAS:SAAS00926160};
KW   Two-component regulatory system {ECO:0000256|RuleBase:RU364088,
KW   ECO:0000256|SAAS:SAAS00924981}.
FT   TRANSMEM     12     36       Helical. {ECO:0000256|RuleBase:RU364088}.
FT   TRANSMEM    187    206       Helical. {ECO:0000256|RuleBase:RU364088}.
FT   DOMAIN      207    260       HAMP. {ECO:0000259|PROSITE:PS50885}.
FT   DOMAIN      268    482       Histidine kinase. {ECO:0000259|PROSITE:
FT                                PS50109}.
SQ   SEQUENCE   482 AA;  54234 MW;  CF5D22A8F0B17557 CRC64;
     MVSKPFQRPF SLATRLTFFI SLATIAAFFA FAWIMIHSVK VHFAEQDIND LKEISATLER
     VLNHPDETQA RRLMTLEDIV SGYSNVLISL ADSHGKTVYH SPGAPDIREF TRDAIPDKDA
     QGGEVYLLSG PTIMMPGHGH GHMEHSNWRM INLPVGPLVD GKPIYTLYIA LSIDFHLHYI
     NDLMNKLIMT ASVISILIVF IVLLAVHKGH APIRSVSRQI QNITSKDLDV RLDPQTEPIE
     LEQLVLSFNH MIERIEDVFT RQSNFSADIA HEIRTPITNL ITQTEIALSQ SRSQKELEDV
     LYSNLEELTR MAKMVSDMLF LAQADNNQLI PEKKMLNLAD EVGKVFDFFE ALAEDRGVEL
     RFVGDKCQVA GDPLMLRRAL SNLLSNALRY TPTRETIVVR CQTVDHQVQV TVENPGTPIA
     PEHLPRLFDR FYRVDPSRQR KGEGSGIGLA IVKSIVVAHK GTVAVTSDAR GTRFVIMLPE
     RE
//