(data stored in SCRATCH zone)

SWISSPROT: Q3Z5I3_SHISS

ID   Q3Z5I3_SHISS            Unreviewed;       249 AA.
AC   Q3Z5I3;
DT   27-SEP-2005, integrated into UniProtKB/TrEMBL.
DT   27-SEP-2005, sequence version 1.
DT   08-MAY-2019, entry version 81.
DE   RecName: Full=Phosphatidate cytidylyltransferase {ECO:0000256|RuleBase:RU003938};
DE            EC=2.7.7.41 {ECO:0000256|RuleBase:RU003938};
GN   Name=cdsA {ECO:0000313|EMBL:AAZ86979.1};
GN   OrderedLocusNames=SSON_0187 {ECO:0000313|EMBL:AAZ86979.1};
OS   Shigella sonnei (strain Ss046).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=300269 {ECO:0000313|EMBL:AAZ86979.1, ECO:0000313|Proteomes:UP000002529};
RN   [1] {ECO:0000313|EMBL:AAZ86979.1, ECO:0000313|Proteomes:UP000002529}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ss046 {ECO:0000313|EMBL:AAZ86979.1,
RC   ECO:0000313|Proteomes:UP000002529};
RX   PubMed=16275786; DOI=10.1093/nar/gki954;
RA   Yang F., Yang J., Zhang X., Chen L., Jiang Y., Yan Y., Tang X.,
RA   Wang J., Xiong Z., Dong J., Xue Y., Zhu Y., Xu X., Sun L., Chen S.,
RA   Nie H., Peng J., Xu J., Wang Y., Yuan Z., Wen Y., Yao Z., Shen Y.,
RA   Qiang B., Hou Y., Yu J., Jin Q.;
RT   "Genome dynamics and diversity of Shigella species, the etiologic
RT   agents of bacillary dysentery.";
RL   Nucleic Acids Res. 33:6445-6458(2005).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a 1,2-diacyl-sn-glycero-3-phosphate + CTP + H(+) = a CDP-
CC         1,2-diacyl-sn-glycerol + diphosphate; Xref=Rhea:RHEA:16229,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:33019, ChEBI:CHEBI:37563,
CC         ChEBI:CHEBI:58332, ChEBI:CHEBI:58608; EC=2.7.7.41;
CC         Evidence={ECO:0000256|RuleBase:RU003938};
CC   -!- PATHWAY: Phospholipid metabolism; CDP-diacylglycerol biosynthesis;
CC       CDP-diacylglycerol from sn-glycerol 3-phosphate: step 3/3.
CC       {ECO:0000256|RuleBase:RU003938}.
CC   -!- SIMILARITY: Belongs to the CDS family.
CC       {ECO:0000256|RuleBase:RU003938}.
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DR   EMBL; CP000038; AAZ86979.1; -; Genomic_DNA.
DR   EnsemblBacteria; AAZ86979; AAZ86979; SSON_0187.
DR   KEGG; ssn:SSON_0187; -.
DR   HOGENOM; HOG000006168; -.
DR   KO; K00981; -.
DR   OMA; WEWGRLN; -.
DR   UniPathway; UPA00557; UER00614.
DR   Proteomes; UP000002529; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004605; F:phosphatidate cytidylyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016024; P:CDP-diacylglycerol biosynthetic process; IEA:UniProtKB-UniPathway.
DR   InterPro; IPR000374; PC_trans.
DR   PROSITE; PS01315; CDS; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q3Z5I3.
DR   SWISS-2DPAGE; Q3Z5I3.
KW   Complete proteome {ECO:0000313|Proteomes:UP000002529};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Nucleotidyltransferase {ECO:0000256|RuleBase:RU003938};
KW   Transferase {ECO:0000256|RuleBase:RU003938};
KW   Transmembrane {ECO:0000256|RuleBase:RU003938,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     20     37       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     57     77       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     84    105       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    117    135       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    156    174       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    180    198       Helical. {ECO:0000256|SAM:Phobius}.
SQ   SEQUENCE   249 AA;  27571 MW;  F628EC847F193647 CRC64;
     MLAAWEWGQL SGFTTRSQRV WLAVLCGLLL ALMLFLLPEY HRNIHQPLVE ISLWASLGWW
     IVALLLVLFY PGSAAIWRNS KTLRLIFGVL TIVPFFWGML ALRAWHYDEN HYSGAIWLLY
     VMILVWGADS GAYMFGKLFG KHKLAPKVSP GKTWQGFIGG LATAAVISWG YGMWANLDVA
     PVTLLICSIV AALASVLGDL TESMFKREAG IKDSGHLIPG HGGILDRIDS LTAAVPVFAC
     LLLLVFRTL
//

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