(data stored in SCRATCH zone)

SWISSPROT: Q47SV9_THEFY

ID   Q47SV9_THEFY            Unreviewed;       422 AA.
AC   Q47SV9;
DT   13-SEP-2005, integrated into UniProtKB/TrEMBL.
DT   13-SEP-2005, sequence version 1.
DT   08-MAY-2019, entry version 113.
DE   RecName: Full=Sulfate adenylyltransferase subunit 1 {ECO:0000256|SAAS:SAAS01159121};
DE            EC=2.7.7.4 {ECO:0000256|SAAS:SAAS01159100};
GN   OrderedLocusNames=Tfu_0420 {ECO:0000313|EMBL:AAZ54458.1};
OS   Thermobifida fusca (strain YX).
OC   Bacteria; Actinobacteria; Streptosporangiales; Nocardiopsaceae;
OC   Thermobifida.
OX   NCBI_TaxID=269800 {ECO:0000313|EMBL:AAZ54458.1, ECO:0000313|Proteomes:UP000000434};
RN   [1] {ECO:0000313|Proteomes:UP000000434}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YX {ECO:0000313|Proteomes:UP000000434};
RX   PubMed=17209016; DOI=10.1128/JB.01899-06;
RA   Lykidis A., Mavromatis K., Ivanova N., Anderson I., Land M.,
RA   DiBartolo G., Martinez M., Lapidus A., Lucas S., Copeland A.,
RA   Richardson P., Wilson D.B., Kyrpides N.;
RT   "Genome sequence and analysis of the soil cellulolytic actinomycete
RT   Thermobifida fusca YX.";
RL   J. Bacteriol. 189:2477-2486(2007).
CC   -!- FUNCTION: May be the GTPase, regulating ATP sulfurylase activity.
CC       {ECO:0000256|SAAS:SAAS01159112}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H(+) + sulfate = adenosine 5'-phosphosulfate +
CC         diphosphate; Xref=Rhea:RHEA:18133, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:16189, ChEBI:CHEBI:30616, ChEBI:CHEBI:33019,
CC         ChEBI:CHEBI:58243; EC=2.7.7.4;
CC         Evidence={ECO:0000256|SAAS:SAAS01159104};
CC   -!- PATHWAY: Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite
CC       from sulfate: step 1/3. {ECO:0000256|SAAS:SAAS01159102}.
CC   -!- SUBUNIT: Heterodimer composed of CysD, the smaller subunit, and
CC       CysN. {ECO:0000256|SAAS:SAAS01159116}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class translation factor GTPase
CC       superfamily. Classic translation factor GTPase family. CysN/NodQ
CC       subfamily. {ECO:0000256|SAAS:SAAS01159111}.
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DR   EMBL; CP000088; AAZ54458.1; -; Genomic_DNA.
DR   RefSeq; WP_011290867.1; NC_007333.1.
DR   STRING; 269800.Tfu_0420; -.
DR   EnsemblBacteria; AAZ54458; AAZ54458; Tfu_0420.
DR   KEGG; tfu:Tfu_0420; -.
DR   eggNOG; ENOG4105C3T; Bacteria.
DR   eggNOG; COG2895; LUCA.
DR   HOGENOM; HOG000229289; -.
DR   KO; K00956; -.
DR   OMA; SRGDMIC; -.
DR   OrthoDB; 244339at2; -.
DR   BioCyc; TFUS269800:G1G4Q-426-MONOMER; -.
DR   UniPathway; UPA00140; UER00204.
DR   Proteomes; UP000000434; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0004781; F:sulfate adenylyltransferase (ATP) activity; IEA:UniProtKB-EC.
DR   GO; GO:0070814; P:hydrogen sulfide biosynthetic process; IEA:UniProtKB-UniPathway.
DR   CDD; cd04166; CysN_ATPS; 1.
DR   InterPro; IPR041757; CysN_GTP-bd.
DR   InterPro; IPR031157; G_TR_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR005225; Small_GTP-bd_dom.
DR   InterPro; IPR011779; SO4_adenylTrfase_lsu.
DR   InterPro; IPR000795; TF_GTP-bd_dom.
DR   InterPro; IPR009000; Transl_B-barrel_sf.
DR   InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR   Pfam; PF00009; GTP_EFTU; 1.
DR   PRINTS; PR00315; ELONGATNFCT.
DR   SUPFAM; SSF50447; SSF50447; 1.
DR   SUPFAM; SSF50465; SSF50465; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR02034; CysN; 1.
DR   TIGRFAMs; TIGR00231; small_GTP; 1.
DR   PROSITE; PS00301; G_TR_1; 1.
DR   PROSITE; PS51722; G_TR_2; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q47SV9.
DR   SWISS-2DPAGE; Q47SV9.
KW   ATP-binding {ECO:0000256|SAAS:SAAS01159110};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000434};
KW   GTP-binding {ECO:0000256|SAAS:SAAS01159120};
KW   Nucleotide-binding {ECO:0000256|SAAS:SAAS01159098};
KW   Nucleotidyltransferase {ECO:0000256|SAAS:SAAS01159099,
KW   ECO:0000313|EMBL:AAZ54458.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000434};
KW   Transferase {ECO:0000256|SAAS:SAAS01159119,
KW   ECO:0000313|EMBL:AAZ54458.1}.
FT   DOMAIN        3    216       Tr-type G. {ECO:0000259|PROSITE:PS51722}.
SQ   SEQUENCE   422 AA;  46889 MW;  93D904D6B12E0195 CRC64;
     MATDILRFAT AGSVDDGKST LIGRLLYDTK SILEDQYEAV KRTSLARGED QANLALLTDG
     LRAEREQGIT IDVAYRYFAT PRRTFIIADT PGHIQYTRNM VTGASTADLA VILVDARKGV
     QEQSRRHAFL TTLLQVPHLV LAVNKMDLVG YSQERFEEIK AEFTEFAAKL DVRDLAFIPI
     SALHGDNVVE RSAAMPWYDG PSLLQHLETV HIASDRNLVD ARFPVQYVIR PYRADDPELH
     DYRGYAGQVT SGVLRPGDEV VHLPSGMATR IQRIVTADGD VAEAFPPMSV TLLLEDDIDI
     SRGDMICRPH NQPTVTQDLD AMVCWMSEGP PLAPRTKLLI KHTTRVAKVM VRDLLYRIDT
     TTLERDESAT SLALNEIGRV KLRVAQPLFV DEYRRNRLTG GFILIDEGTN ATVGAGMITQ
     AG
//

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