(data stored in SCRATCH zone)

SWISSPROT: Q47SZ3_THEFY

ID   Q47SZ3_THEFY            Unreviewed;       289 AA.
AC   Q47SZ3;
DT   13-SEP-2005, integrated into UniProtKB/TrEMBL.
DT   13-SEP-2005, sequence version 1.
DT   08-MAY-2019, entry version 88.
DE   RecName: Full=Ribosomal RNA small subunit methyltransferase I {ECO:0000256|HAMAP-Rule:MF_01877};
DE            EC=2.1.1.198 {ECO:0000256|HAMAP-Rule:MF_01877};
DE   AltName: Full=16S rRNA 2'-O-ribose C1402 methyltransferase {ECO:0000256|HAMAP-Rule:MF_01877};
DE   AltName: Full=rRNA (cytidine-2'-O-)-methyltransferase RsmI {ECO:0000256|HAMAP-Rule:MF_01877};
GN   Name=rsmI {ECO:0000256|HAMAP-Rule:MF_01877};
GN   OrderedLocusNames=Tfu_0386 {ECO:0000313|EMBL:AAZ54424.1};
OS   Thermobifida fusca (strain YX).
OC   Bacteria; Actinobacteria; Streptosporangiales; Nocardiopsaceae;
OC   Thermobifida.
OX   NCBI_TaxID=269800 {ECO:0000313|EMBL:AAZ54424.1, ECO:0000313|Proteomes:UP000000434};
RN   [1] {ECO:0000313|Proteomes:UP000000434}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YX {ECO:0000313|Proteomes:UP000000434};
RX   PubMed=17209016; DOI=10.1128/JB.01899-06;
RA   Lykidis A., Mavromatis K., Ivanova N., Anderson I., Land M.,
RA   DiBartolo G., Martinez M., Lapidus A., Lucas S., Copeland A.,
RA   Richardson P., Wilson D.B., Kyrpides N.;
RT   "Genome sequence and analysis of the soil cellulolytic actinomycete
RT   Thermobifida fusca YX.";
RL   J. Bacteriol. 189:2477-2486(2007).
CC   -!- FUNCTION: Catalyzes the 2'-O-methylation of the ribose of cytidine
CC       1402 (C1402) in 16S rRNA. {ECO:0000256|HAMAP-Rule:MF_01877}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=cytidine(1402) in 16S rRNA + S-adenosyl-L-methionine =
CC         2'-O-methylcytidine(1402) in 16S rRNA + H(+) + S-adenosyl-L-
CC         homocysteine; Xref=Rhea:RHEA:42924, Rhea:RHEA-COMP:10285,
CC         Rhea:RHEA-COMP:10286, ChEBI:CHEBI:15378, ChEBI:CHEBI:57856,
CC         ChEBI:CHEBI:59789, ChEBI:CHEBI:74495, ChEBI:CHEBI:82748;
CC         EC=2.1.1.198; Evidence={ECO:0000256|HAMAP-Rule:MF_01877};
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01877}.
CC   -!- SIMILARITY: Belongs to the methyltransferase superfamily. RsmI
CC       family. {ECO:0000256|HAMAP-Rule:MF_01877}.
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DR   EMBL; CP000088; AAZ54424.1; -; Genomic_DNA.
DR   RefSeq; WP_011290833.1; NC_007333.1.
DR   STRING; 269800.Tfu_0386; -.
DR   EnsemblBacteria; AAZ54424; AAZ54424; Tfu_0386.
DR   KEGG; tfu:Tfu_0386; -.
DR   eggNOG; ENOG4105CU0; Bacteria.
DR   eggNOG; COG0313; LUCA.
DR   HOGENOM; HOG000195940; -.
DR   KO; K07056; -.
DR   OMA; RTMVFFE; -.
DR   OrthoDB; 1059309at2; -.
DR   BioCyc; TFUS269800:G1G4Q-390-MONOMER; -.
DR   Proteomes; UP000000434; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0070677; F:rRNA (cytosine-2'-O-)-methyltransferase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0000453; P:enzyme-directed rRNA 2'-O-methylation; IEA:UniProtKB-UniRule.
DR   CDD; cd11648; RsmI; 1.
DR   Gene3D; 3.30.950.10; -; 1.
DR   Gene3D; 3.40.1010.10; -; 1.
DR   HAMAP; MF_01877; 16SrRNA_methyltr_I; 1.
DR   InterPro; IPR000878; 4pyrrol_Mease.
DR   InterPro; IPR035996; 4pyrrol_Methylase_sf.
DR   InterPro; IPR014777; 4pyrrole_Mease_sub1.
DR   InterPro; IPR014776; 4pyrrole_Mease_sub2.
DR   InterPro; IPR008189; rRNA_ssu_MeTfrase_I.
DR   PANTHER; PTHR46111; PTHR46111; 1.
DR   Pfam; PF00590; TP_methylase; 1.
DR   PIRSF; PIRSF005917; MTase_YraL; 1.
DR   SUPFAM; SSF53790; SSF53790; 1.
DR   TIGRFAMs; TIGR00096; TIGR00096; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q47SZ3.
DR   SWISS-2DPAGE; Q47SZ3.
KW   Complete proteome {ECO:0000313|Proteomes:UP000000434};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01877};
KW   Methyltransferase {ECO:0000256|HAMAP-Rule:MF_01877};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000434};
KW   rRNA processing {ECO:0000256|HAMAP-Rule:MF_01877};
KW   S-adenosyl-L-methionine {ECO:0000256|HAMAP-Rule:MF_01877};
KW   Transferase {ECO:0000256|HAMAP-Rule:MF_01877}.
FT   DOMAIN       12    217       TP_methylase. {ECO:0000259|Pfam:PF00590}.
SQ   SEQUENCE   289 AA;  31015 MW;  05B051CC35C769C6 CRC64;
     MADQQSSTRP GTLTLAGLPI GHRDDTTPRL RAALENAEII AAEDTRRLRQ FAARIGVRPG
     GKRGARIVSY YDANERERAA ELLADLQAGH DVLLVTDAGM PGVSDPGYRL ITACVDAGVP
     MTVIPGPSAV TAALVLSGLP TDRFCFEGFP PRKGLAAYLA GLADERRTMV FFEAPHRLAA
     TLTAMADAFG PDRPAAVCRE LTKTYEEVRR GGLAELAEWA AEHARGEITL VVRGAERTTP
     QATPEALVAA VAAREDQGVP RKQAIQQVAQ EYGVPKREVY NAVHRTPSD
//

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