(data stored in SCRATCH zone)

SWISSPROT: Q47T63_THEFY

ID   Q47T63_THEFY            Unreviewed;       511 AA.
AC   Q47T63;
DT   13-SEP-2005, integrated into UniProtKB/TrEMBL.
DT   13-SEP-2005, sequence version 1.
DT   08-MAY-2019, entry version 76.
DE   SubName: Full=Precorrin-2 C20-methyltransferase / precorrin-3 methyltransferase {ECO:0000313|EMBL:AAZ54354.1};
DE            EC=2.1.1.130 {ECO:0000313|EMBL:AAZ54354.1};
DE            EC=2.1.1.131 {ECO:0000313|EMBL:AAZ54354.1};
GN   OrderedLocusNames=Tfu_0316 {ECO:0000313|EMBL:AAZ54354.1};
OS   Thermobifida fusca (strain YX).
OC   Bacteria; Actinobacteria; Streptosporangiales; Nocardiopsaceae;
OC   Thermobifida.
OX   NCBI_TaxID=269800 {ECO:0000313|EMBL:AAZ54354.1, ECO:0000313|Proteomes:UP000000434};
RN   [1] {ECO:0000313|Proteomes:UP000000434}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YX {ECO:0000313|Proteomes:UP000000434};
RX   PubMed=17209016; DOI=10.1128/JB.01899-06;
RA   Lykidis A., Mavromatis K., Ivanova N., Anderson I., Land M.,
RA   DiBartolo G., Martinez M., Lapidus A., Lucas S., Copeland A.,
RA   Richardson P., Wilson D.B., Kyrpides N.;
RT   "Genome sequence and analysis of the soil cellulolytic actinomycete
RT   Thermobifida fusca YX.";
RL   J. Bacteriol. 189:2477-2486(2007).
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DR   EMBL; CP000088; AAZ54354.1; -; Genomic_DNA.
DR   RefSeq; WP_011290763.1; NC_007333.1.
DR   STRING; 269800.Tfu_0316; -.
DR   EnsemblBacteria; AAZ54354; AAZ54354; Tfu_0316.
DR   KEGG; tfu:Tfu_0316; -.
DR   eggNOG; ENOG4105E4R; Bacteria.
DR   eggNOG; COG1010; LUCA.
DR   eggNOG; COG2243; LUCA.
DR   HOGENOM; HOG000047670; -.
DR   KO; K13540; -.
DR   OMA; YMHMHKR; -.
DR   OrthoDB; 1195697at2; -.
DR   BioCyc; TFUS269800:G1G4Q-318-MONOMER; -.
DR   Proteomes; UP000000434; Chromosome.
DR   GO; GO:0030788; F:precorrin-2 C20-methyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030789; F:precorrin-3B C17-methyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009236; P:cobalamin biosynthetic process; IEA:InterPro.
DR   CDD; cd11645; Precorrin_2_C20_MT; 1.
DR   CDD; cd11646; Precorrin_3B_C17_MT; 1.
DR   Gene3D; 3.30.950.10; -; 2.
DR   Gene3D; 3.40.1010.10; -; 2.
DR   InterPro; IPR000878; 4pyrrol_Mease.
DR   InterPro; IPR035996; 4pyrrol_Methylase_sf.
DR   InterPro; IPR014777; 4pyrrole_Mease_sub1.
DR   InterPro; IPR014776; 4pyrrole_Mease_sub2.
DR   InterPro; IPR006363; Cbl_synth_CobJ/CibH_dom.
DR   InterPro; IPR012382; CobI/CbiL.
DR   InterPro; IPR006364; CobI/CbiL/CobIJ_dom.
DR   Pfam; PF00590; TP_methylase; 2.
DR   SUPFAM; SSF53790; SSF53790; 2.
DR   TIGRFAMs; TIGR01467; cobI_cbiL; 1.
DR   TIGRFAMs; TIGR01466; cobJ_cbiH; 1.
PE   4: Predicted;
DR   PRODOM; Q47T63.
DR   SWISS-2DPAGE; Q47T63.
KW   Complete proteome {ECO:0000313|Proteomes:UP000000434};
KW   Methyltransferase {ECO:0000313|EMBL:AAZ54354.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000434};
KW   Transferase {ECO:0000313|EMBL:AAZ54354.1}.
FT   DOMAIN        7    220       TP_methylase. {ECO:0000259|Pfam:PF00590}.
FT   DOMAIN      271    477       TP_methylase. {ECO:0000259|Pfam:PF00590}.
SQ   SEQUENCE   511 AA;  54246 MW;  DBE4FE592B34BB9E CRC64;
     MSSTPGRLYG VGLGPGDPEF ITRKAARLIA EADVIAYYSG THGRSIARSI AADVIPEGVI
     EEKLVYPVTT GTTDHPGGYE GAITEFYDAS AQRLAAHLSQ GRDVVVLCEG DPLFYGSYMY
     LHDRLASRFP TEIVPGVTSI SAASAAAACP LVRRTDVLTI LPGTLPPPEL ARRLADTDAA
     AVLKLGRRTF AGVREALAQA GRLEDAVYVE RASMAEQRIL PVGDVASDDV PYFSLILSSG
     DSTPRNRRPR GRVRAPQRTP APHHPDSPAE LLVVGLGPAG EQWLTPEAAQ ALANVDHVVG
     YGPYVDRVPV RPGQQRHSSG NTVELDRARF ALDLALAGER VAVVSGGDAG VFGMASAVFE
     AAQDPRYADV PVRVLPGLTA VQAVAARAGA PIGGDFAVLS LSDRLKPWEV IEARLEAAAR
     ADLVLAIYNP ASRSRRTQVA RARDVLLRHR RDNTPVVVGR DVGREGESVE VTTLGKLDPE
     GIDMRCLLIV GSSSTSVTAA GAVWTPRFVA E
//

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