(data stored in ACNUC8465 zone)

SWISSPROT: Q4H379_CIOIN

ID   Q4H379_CIOIN            Unreviewed;       478 AA.
AC   Q4H379; A0A1W2VNM5;
DT   30-AUG-2005, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2005, sequence version 1.
DT   11-DEC-2019, entry version 73.
DE   SubName: Full=Mitogen-activated protein kinase kinase {ECO:0000313|EMBL:BAE06548.1, ECO:0000313|RefSeq:NP_001071759.1};
GN   Name=Ci-MAPKK7 {ECO:0000313|EMBL:BAE06548.1};
GN   Synonyms=mapkk7 {ECO:0000313|RefSeq:NP_001071759.1};
OS   Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis).
OC   Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Enterogona;
OC   Phlebobranchia; Cionidae; Ciona.
OX   NCBI_TaxID=7719 {ECO:0000313|EMBL:BAE06548.1};
RN   [1] {ECO:0000313|RefSeq:NP_001071759.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=12203911;
RA   Satou Y., Yamada L., Mochizuki Y., Takatori N., Kawashima T., Sasaki A.,
RA   Hamaguchi M., Awazu S., Yagi K., Sasakura Y., Nakayama A., Ishikawa H.,
RA   Inaba K., Satoh N.;
RT   "A cDNA resource from the basal chordate Ciona intestinalis.";
RL   Genesis 33:153-154(2002).
RN   [2] {ECO:0000313|EMBL:BAE06548.1, ECO:0000313|RefSeq:NP_001071759.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=12736827; DOI=10.1007/s00427-003-0330-z;
RA   Satou Y., Satoh N.;
RT   "Genomewide surveys of developmentally relevant genes in Ciona
RT   intestinalis.";
RL   Dev. Genes Evol. 213:211-212(2003).
RN   [3] {ECO:0000313|EMBL:BAE06548.1, ECO:0000313|RefSeq:NP_001071759.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=15269171; DOI=10.1242/dev.01270;
RA   Imai K.S., Hino K., Yagi K., Satoh N., Satou Y.;
RT   "Gene expression profiles of transcription factors and signaling molecules
RT   in the ascidian embryo: towards a comprehensive understanding of gene
RT   networks.";
RL   Development 131:4047-4058(2004).
RN   [4] {ECO:0000313|RefSeq:NP_001071759.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=16141696;
RA   Satou Y., Kawashima T., Shoguchi E., Nakayama A., Satoh N.;
RT   "An integrated database of the ascidian, Ciona intestinalis: towards
RT   functional genomics.";
RL   Zool. Sci. 22:837-843(2005).
RN   [5] {ECO:0000313|EMBL:BAE06548.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Satou Y.;
RT   "Expressed genes in Ciona intestinalis.";
RL   Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
RN   [6] {ECO:0000313|RefSeq:NP_001071759.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (MAR-2019) to UniProtKB.
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DR   EMBL; AB210543; BAE06548.1; -; mRNA.
DR   RefSeq; NP_001071759.1; NM_001078291.1.
DR   STRING; 7719.NP_001071759.1; -.
DR   GeneID; 778674; -.
DR   KEGG; cin:778674; -.
DR   CTD; 778674; -.
DR   eggNOG; KOG0983; Eukaryota.
DR   eggNOG; ENOG410XTNQ; LUCA.
DR   HOGENOM; HOG000234206; -.
DR   KO; K04431; -.
DR   OrthoDB; 688282at2759; -.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR000719; Prot_kinase_dom.
DR   InterPro; IPR008271; Ser/Thr_kinase_AS.
DR   Pfam; PF00069; Pkinase; 1.
DR   SMART; SM00220; S_TKc; 1.
DR   SUPFAM; SSF56112; SSF56112; 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR   PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE   2: Evidence at transcript level;
DR   PRODOM; Q4H379.
DR   SWISS-2DPAGE; Q4H379.
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Kinase {ECO:0000313|EMBL:BAE06548.1, ECO:0000313|RefSeq:NP_001071759.1};
KW   Transferase {ECO:0000313|EMBL:BAE06548.1,
KW   ECO:0000313|RefSeq:NP_001071759.1}.
FT   DOMAIN          130..388
FT                   /note="Protein kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50011"
FT   REGION          31..52
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          456..478
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          9..29
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   478 AA;  53875 MW;  7D80B2C987A2C9BA CRC64;
     MTMNGSVDLN ALEKRMKQLE LNFQQQNARK KPTNLGMGNM SNSQQTSSAR PHMSLNFSNS
     SPASLMKSSS GAVDTAARKK QISFALPASI PQPEKTQESE KIDARLQEVI RQTGKLRIDS
     MIYEAKVEQF ENLGQIGSGT CGQVYKMRYI TGHVMAVKQM HRSGNREENK RILMDLDIVQ
     KSHDCPNIVK CYGTFVTEVN VWICMELMET CFDKLKKKIN GPMPENILGK LTVSVVKALH
     YLKEKHGVIH RDVKPSNILV NKLGDVKLCD FGISGRLVDS QAKTRAAGCT AYMAPERISP
     DPSHPNYDIR ADVWSLGISL VELATGVFPY HNCKTDFEML TKILEEAPPE LPNDQNFSIG
     FKRFVSFCCT KDYRYRPKYR DLLEHEFVRR HEHSMVDIPA WLRKVLITQT KAASLDRCGN
     PMQGNIASSN DPFAFAAEIT KAQFAKHTRT RSLGTGFEFT KIPPNQTNKP TSSKSIFR
//

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