(data stored in SCRATCH zone)

SWISSPROT: Q4W957_ASPFU

ID   Q4W957_ASPFU            Unreviewed;       348 AA.
AC   Q4W957;
DT   05-JUL-2005, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2005, sequence version 1.
DT   11-DEC-2019, entry version 76.
DE   RecName: Full=Fatty acid hydroxylase domain-containing protein {ECO:0000259|Pfam:PF04116};
GN   ORFNames=AFUA_4G00340 {ECO:0000313|EMBL:EAL84384.1};
OS   Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC
OS   A1100) (Aspergillus fumigatus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX   NCBI_TaxID=330879 {ECO:0000313|EMBL:EAL84384.1, ECO:0000313|Proteomes:UP000002530};
RN   [1] {ECO:0000313|EMBL:EAL84384.1, ECO:0000313|Proteomes:UP000002530}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100
RC   {ECO:0000313|Proteomes:UP000002530};
RX   PubMed=16372009; DOI=10.1038/nature04332;
RA   Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J.,
RA   Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J., Bowyer P.,
RA   Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.,
RA   Fedorova N., Fedorova N., Feldblyum T.V., Fischer R., Fosker N., Fraser A.,
RA   Garcia J.L., Garcia M.J., Goble A., Goldman G.H., Gomi K.,
RA   Griffith-Jones S., Gwilliam R., Haas B., Haas H., Harris D., Horiuchi H.,
RA   Huang J., Humphray S., Jimenez J., Keller N., Khouri H., Kitamoto K.,
RA   Kobayashi T., Konzack S., Kulkarni R., Kumagai T., Lafon A., Latge J.P.,
RA   Li W., Lord A., Lu C., Majoros W.H., May G.S., Miller B.L., Mohamoud Y.,
RA   Molina M., Monod M., Mouyna I., Mulligan S., Murphy L., O'Neil S.,
RA   Paulsen I., Penalva M.A., Pertea M., Price C., Pritchard B.L., Quail M.A.,
RA   Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U., Renauld H.,
RA   Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M., Ronning C.M.,
RA   Rutter S., Salzberg S.L., Sanchez M., Sanchez-Ferrero J.C., Saunders D.,
RA   Seeger K., Squares R., Squares S., Takeuchi M., Tekaia F., Turner G.,
RA   Vazquez de Aldana C.R., Weidman J., White O., Woodward J., Yu J.H.,
RA   Fraser C., Galagan J.E., Asai K., Machida M., Hall N., Barrell B.,
RA   Denning D.W.;
RT   "Genomic sequence of the pathogenic and allergenic filamentous fungus
RT   Aspergillus fumigatus.";
RL   Nature 438:1151-1156(2005).
CC   -!- SIMILARITY: Belongs to the sterol desaturase family.
CC       {ECO:0000256|SAAS:SAAS00565350}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EAL84384.1}.
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DR   EMBL; AAHF01000017; EAL84384.1; -; Genomic_DNA.
DR   RefSeq; XP_746422.1; XM_741329.1.
DR   EnsemblFungi; EAL84384; EAL84384; AFUA_4G00340.
DR   GeneID; 3503739; -.
DR   KEGG; afm:AFUA_4G00340; -.
DR   EuPathDB; FungiDB:Afu4g00340; -.
DR   HOGENOM; HOG000175373; -.
DR   InParanoid; Q4W957; -.
DR   OMA; DHEQEFG; -.
DR   OrthoDB; 1493916at2759; -.
DR   Proteomes; UP000002530; Chromosome 4.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IBA:GO_Central.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0008610; P:lipid biosynthetic process; IEA:InterPro.
DR   InterPro; IPR006694; Fatty_acid_hydroxylase.
DR   Pfam; PF04116; FA_hydroxylase; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q4W957.
DR   SWISS-2DPAGE; Q4W957.
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002530};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        61..81
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        93..111
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        170..191
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          179..325
FT                   /note="Fatty acid hydroxylase"
FT                   /evidence="ECO:0000259|Pfam:PF04116"
SQ   SEQUENCE   348 AA;  41196 MW;  1FDB365B9DA20A4B CRC64;
     METKGNPKDS MKSTWRTASR DTWSLGHWLI HILNAYPLEL DKEVPVHSKD EPIPFMPQWS
     LNLWVIFYSS LPLLFHQAYA WYTERNLGPL ATFNLYMFAF NAIVIYQVHI LRRLGHIYGF
     LDGDKHERDG IPDVGVGKVV ASVYKTTGSR LALSVYFSYQ TSQLPAQMNW YWLPVEVGLY
     GIVLDFWFYW YHRLMHDVSF LWKYHRTHHL TKHPNPLLTA YADHEQEFGD MVGVPMMTYF
     TLRLLGLPMG FYEWWICHEY VVFAEVFGHS GLRLHLTVPS PLSWLMQWLD AEIVIEDHDL
     HHRKGWRKSH NYGKQTRLWD RIFGTCHERI ESAPENVDYV NTARMPLF
//

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