(data stored in SCRATCH zone)

SWISSPROT: Q4W9S2_ASPFU

ID   Q4W9S2_ASPFU            Unreviewed;       535 AA.
AC   Q4W9S2;
DT   05-JUL-2005, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2005, sequence version 1.
DT   11-DEC-2019, entry version 87.
DE   SubName: Full=MFS drug transporter, putative {ECO:0000313|EMBL:EAL84541.1};
GN   ORFNames=AFUA_4G03920 {ECO:0000313|EMBL:EAL84541.1};
OS   Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC
OS   A1100) (Aspergillus fumigatus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX   NCBI_TaxID=330879 {ECO:0000313|EMBL:EAL84541.1, ECO:0000313|Proteomes:UP000002530};
RN   [1] {ECO:0000313|EMBL:EAL84541.1, ECO:0000313|Proteomes:UP000002530}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100
RC   {ECO:0000313|Proteomes:UP000002530};
RX   PubMed=16372009; DOI=10.1038/nature04332;
RA   Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J.,
RA   Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J., Bowyer P.,
RA   Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.,
RA   Fedorova N., Fedorova N., Feldblyum T.V., Fischer R., Fosker N., Fraser A.,
RA   Garcia J.L., Garcia M.J., Goble A., Goldman G.H., Gomi K.,
RA   Griffith-Jones S., Gwilliam R., Haas B., Haas H., Harris D., Horiuchi H.,
RA   Huang J., Humphray S., Jimenez J., Keller N., Khouri H., Kitamoto K.,
RA   Kobayashi T., Konzack S., Kulkarni R., Kumagai T., Lafon A., Latge J.P.,
RA   Li W., Lord A., Lu C., Majoros W.H., May G.S., Miller B.L., Mohamoud Y.,
RA   Molina M., Monod M., Mouyna I., Mulligan S., Murphy L., O'Neil S.,
RA   Paulsen I., Penalva M.A., Pertea M., Price C., Pritchard B.L., Quail M.A.,
RA   Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U., Renauld H.,
RA   Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M., Ronning C.M.,
RA   Rutter S., Salzberg S.L., Sanchez M., Sanchez-Ferrero J.C., Saunders D.,
RA   Seeger K., Squares R., Squares S., Takeuchi M., Tekaia F., Turner G.,
RA   Vazquez de Aldana C.R., Weidman J., White O., Woodward J., Yu J.H.,
RA   Fraser C., Galagan J.E., Asai K., Machida M., Hall N., Barrell B.,
RA   Denning D.W.;
RT   "Genomic sequence of the pathogenic and allergenic filamentous fungus
RT   Aspergillus fumigatus.";
RL   Nature 438:1151-1156(2005).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EAL84541.1}.
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DR   EMBL; AAHF01000016; EAL84541.1; -; Genomic_DNA.
DR   RefSeq; XP_746579.1; XM_741486.1.
DR   EnsemblFungi; EAL84541; EAL84541; AFUA_4G03920.
DR   GeneID; 3503922; -.
DR   KEGG; afm:AFUA_4G03920; -.
DR   EuPathDB; FungiDB:Afu4g03920; -.
DR   HOGENOM; HOG000170863; -.
DR   InParanoid; Q4W9S2; -.
DR   OMA; SGLVVHW; -.
DR   OrthoDB; 1044694at2759; -.
DR   Proteomes; UP000002530; Chromosome 4.
DR   GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR   GO; GO:0055085; P:transmembrane transport; IBA:GO_Central.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   InterPro; IPR001411; Tet-R_TetB/Drug-R_transptr.
DR   PANTHER; PTHR23501; PTHR23501; 1.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   4: Predicted;
DR   PRODOM; Q4W9S2.
DR   SWISS-2DPAGE; Q4W9S2.
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002530};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        101..121
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        127..148
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        160..182
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        194..216
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        228..249
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        261..280
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        300..320
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        340..361
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        368..385
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        397..416
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        484..504
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          1..508
FT                   /note="MFS"
FT                   /evidence="ECO:0000259|PROSITE:PS50850"
FT   REGION          1..32
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   535 AA;  57361 MW;  5CDAD0EA5D3EA372 CRC64;
     MPDPLISQRQ ESSPSSSSGT IVEVTEGTET KTEGQHVFNE QTNYVPKSTI ITTTLAASLS
     IVGNALNASN QTSWISGAYF VTSTCFQLLY GRLSDIWSRK YVLFAGLAIF FFGSLAASLA
     QTATQLIIFR AFTGIGGGGL MTVAQMIVSD VVPLRERGKY QGILGAVVAI ANGIGPVIGG
     ALASASIEKE SWRWIFRLNL PLTVLTTLCV FFFMPLRKVT GSWKVKLAAV DFVGAALALS
     GTAVLLLGLN WGGGEYAWDS AHVIATLVVG VAVCVAFVLW QWKGAAFPLV PMHIFRSRIV
     NGACLTMFIN GWNFLVQVYY IPTFYQLVFG YSTVKAGAML LPITLLQTAS STASGLVVHW
     IGRYRECILF GWTIWAVGLG LFSTLDQSSG LGKQIGYGIL TGVGVGNTLQ PALIAIQAGV
     DRRDMAVVTS NNILSSSISS LGLTVSETRS FLSSPQNYLS GLSVAEAERV RALVIPAYKR
     GFRIIFVIGG ALAAFAFCLA FALMPQVELN RADDAKLKEE AKKRAAGEDD EKNTC
//

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