(data stored in SCRATCH zone)

SWISSPROT: Q4WCR5_ASPFU

ID   Q4WCR5_ASPFU            Unreviewed;       411 AA.
AC   Q4WCR5;
DT   05-JUL-2005, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2005, sequence version 1.
DT   11-DEC-2019, entry version 78.
DE   SubName: Full=3' exoribonuclease family protein {ECO:0000313|EMBL:EAL85823.1};
DE            EC=3.1.-.- {ECO:0000313|EMBL:EAL85823.1};
GN   ORFNames=AFUA_6G02160 {ECO:0000313|EMBL:EAL85823.1};
OS   Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC
OS   A1100) (Aspergillus fumigatus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX   NCBI_TaxID=330879 {ECO:0000313|EMBL:EAL85823.1, ECO:0000313|Proteomes:UP000002530};
RN   [1] {ECO:0000313|EMBL:EAL85823.1, ECO:0000313|Proteomes:UP000002530}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100
RC   {ECO:0000313|Proteomes:UP000002530};
RX   PubMed=16372009; DOI=10.1038/nature04332;
RA   Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J.,
RA   Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J., Bowyer P.,
RA   Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.,
RA   Fedorova N., Fedorova N., Feldblyum T.V., Fischer R., Fosker N., Fraser A.,
RA   Garcia J.L., Garcia M.J., Goble A., Goldman G.H., Gomi K.,
RA   Griffith-Jones S., Gwilliam R., Haas B., Haas H., Harris D., Horiuchi H.,
RA   Huang J., Humphray S., Jimenez J., Keller N., Khouri H., Kitamoto K.,
RA   Kobayashi T., Konzack S., Kulkarni R., Kumagai T., Lafon A., Latge J.P.,
RA   Li W., Lord A., Lu C., Majoros W.H., May G.S., Miller B.L., Mohamoud Y.,
RA   Molina M., Monod M., Mouyna I., Mulligan S., Murphy L., O'Neil S.,
RA   Paulsen I., Penalva M.A., Pertea M., Price C., Pritchard B.L., Quail M.A.,
RA   Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U., Renauld H.,
RA   Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M., Ronning C.M.,
RA   Rutter S., Salzberg S.L., Sanchez M., Sanchez-Ferrero J.C., Saunders D.,
RA   Seeger K., Squares R., Squares S., Takeuchi M., Tekaia F., Turner G.,
RA   Vazquez de Aldana C.R., Weidman J., White O., Woodward J., Yu J.H.,
RA   Fraser C., Galagan J.E., Asai K., Machida M., Hall N., Barrell B.,
RA   Denning D.W.;
RT   "Genomic sequence of the pathogenic and allergenic filamentous fungus
RT   Aspergillus fumigatus.";
RL   Nature 438:1151-1156(2005).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EAL85823.1}.
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DR   EMBL; AAHF01000012; EAL85823.1; -; Genomic_DNA.
DR   RefSeq; XP_747861.1; XM_742768.1.
DR   STRING; 746128.CADAFUBP00009347; -.
DR   EnsemblFungi; EAL85823; EAL85823; AFUA_6G02160.
DR   GeneID; 3505245; -.
DR   KEGG; afm:AFUA_6G02160; -.
DR   EuPathDB; FungiDB:Afu6g02160; -.
DR   HOGENOM; HOG000229504; -.
DR   InParanoid; Q4WCR5; -.
DR   KO; K12586; -.
DR   OMA; RWILADP; -.
DR   OrthoDB; 1210090at2759; -.
DR   Proteomes; UP000002530; Chromosome 6.
DR   GO; GO:0000177; C:cytoplasmic exosome (RNase complex); IBA:GO_Central.
DR   GO; GO:0000176; C:nuclear exosome (RNase complex); IBA:GO_Central.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0043928; P:exonucleolytic catabolism of deadenylated mRNA; IBA:GO_Central.
DR   GO; GO:0000467; P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:GO_Central.
DR   GO; GO:0071028; P:nuclear mRNA surveillance; IBA:GO_Central.
DR   GO; GO:0071042; P:nuclear polyadenylation-dependent mRNA catabolic process; IBA:GO_Central.
DR   GO; GO:0071035; P:nuclear polyadenylation-dependent rRNA catabolic process; IBA:GO_Central.
DR   GO; GO:0071038; P:nuclear polyadenylation-dependent tRNA catabolic process; IBA:GO_Central.
DR   GO; GO:0034427; P:nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'; IBA:GO_Central.
DR   GO; GO:0016075; P:rRNA catabolic process; IBA:GO_Central.
DR   GO; GO:0034473; P:U1 snRNA 3'-end processing; IBA:GO_Central.
DR   GO; GO:0034475; P:U4 snRNA 3'-end processing; IBA:GO_Central.
DR   GO; GO:0034476; P:U5 snRNA 3'-end processing; IBA:GO_Central.
DR   Gene3D; 3.30.230.70; -; 1.
DR   InterPro; IPR001247; ExoRNase_PH_dom1.
DR   InterPro; IPR036345; ExoRNase_PH_dom2_sf.
DR   InterPro; IPR027408; PNPase/RNase_PH_dom_sf.
DR   InterPro; IPR020568; Ribosomal_S5_D2-typ_fold.
DR   InterPro; IPR033196; Rrp43.
DR   PANTHER; PTHR11097:SF9; PTHR11097:SF9; 1.
DR   Pfam; PF01138; RNase_PH; 1.
DR   SUPFAM; SSF54211; SSF54211; 1.
DR   SUPFAM; SSF55666; SSF55666; 1.
PE   4: Predicted;
DR   PRODOM; Q4WCR5.
DR   SWISS-2DPAGE; Q4WCR5.
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Hydrolase {ECO:0000313|EMBL:EAL85823.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002530}.
FT   DOMAIN          57..270
FT                   /note="RNase_PH"
FT                   /evidence="ECO:0000259|Pfam:PF01138"
FT   REGION          1..21
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          205..225
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   411 AA;  44946 MW;  5CE01E3215A40CB7 CRC64;
     MAPAAASTAA PSAPPSLSLP PSQFARLQPH AYLLAHLSPP PSSNQPSIRA NGRATSQFRV
     TSANTGSLTH TNGSAVVRIG DTAAVCGVRA EILHTDDIAS WSVSRASAPA SINKRRKLID
     TTEKPTVTAN DDNDDEDDES HIQDLNLLVP NLSLSTGCAP GFIPGAPPSA LAQSLSHQIL
     SLLHSTRLVR AEDLRIWYQP PNWGAEELER HNEDEQMDVD AQEGDTSAKS REIKAFWVLY
     IDVMIISLAG NPFDAAWAAV LAALRDTKLP KAWWDVDNEM VVCSEAVSEA HKLSLRGMPV
     ASSFCVFEAD AASGWRKVII PDAEEERKIE ESDRKGIQRR WILADPDGYE ESLSQERICI
     VVDKENGEQG KTVIVKMEKN GGWAADTREL KQLVDISAQR WDDMKRILDS C
//

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