(data stored in SCRATCH zone)

SWISSPROT: Q4WDG8_ASPFU

ID   Q4WDG8_ASPFU            Unreviewed;       244 AA.
AC   Q4WDG8;
DT   05-JUL-2005, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2005, sequence version 1.
DT   11-DEC-2019, entry version 91.
DE   SubName: Full=Imidazoleglycerol-phosphate dehydratase {ECO:0000313|EMBL:EAL85570.1};
DE            EC=4.2.1.19 {ECO:0000313|EMBL:EAL85570.1};
GN   ORFNames=AFUA_6G04700 {ECO:0000313|EMBL:EAL85570.1};
OS   Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC
OS   A1100) (Aspergillus fumigatus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX   NCBI_TaxID=330879 {ECO:0000313|EMBL:EAL85570.1, ECO:0000313|Proteomes:UP000002530};
RN   [1] {ECO:0000313|EMBL:EAL85570.1, ECO:0000313|Proteomes:UP000002530}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100
RC   {ECO:0000313|Proteomes:UP000002530};
RX   PubMed=16372009; DOI=10.1038/nature04332;
RA   Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J.,
RA   Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J., Bowyer P.,
RA   Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.,
RA   Fedorova N., Fedorova N., Feldblyum T.V., Fischer R., Fosker N., Fraser A.,
RA   Garcia J.L., Garcia M.J., Goble A., Goldman G.H., Gomi K.,
RA   Griffith-Jones S., Gwilliam R., Haas B., Haas H., Harris D., Horiuchi H.,
RA   Huang J., Humphray S., Jimenez J., Keller N., Khouri H., Kitamoto K.,
RA   Kobayashi T., Konzack S., Kulkarni R., Kumagai T., Lafon A., Latge J.P.,
RA   Li W., Lord A., Lu C., Majoros W.H., May G.S., Miller B.L., Mohamoud Y.,
RA   Molina M., Monod M., Mouyna I., Mulligan S., Murphy L., O'Neil S.,
RA   Paulsen I., Penalva M.A., Pertea M., Price C., Pritchard B.L., Quail M.A.,
RA   Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U., Renauld H.,
RA   Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M., Ronning C.M.,
RA   Rutter S., Salzberg S.L., Sanchez M., Sanchez-Ferrero J.C., Saunders D.,
RA   Seeger K., Squares R., Squares S., Takeuchi M., Tekaia F., Turner G.,
RA   Vazquez de Aldana C.R., Weidman J., White O., Woodward J., Yu J.H.,
RA   Fraser C., Galagan J.E., Asai K., Machida M., Hall N., Barrell B.,
RA   Denning D.W.;
RT   "Genomic sequence of the pathogenic and allergenic filamentous fungus
RT   Aspergillus fumigatus.";
RL   Nature 438:1151-1156(2005).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EAL85570.1}.
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DR   EMBL; AAHF01000012; EAL85570.1; -; Genomic_DNA.
DR   RefSeq; XP_747608.1; XM_742515.1.
DR   STRING; 746128.CADAFUBP00009097; -.
DR   EnsemblFungi; EAL85570; EAL85570; AFUA_6G04700.
DR   GeneID; 3505057; -.
DR   KEGG; afm:AFUA_6G04700; -.
DR   EuPathDB; FungiDB:Afu6g04700; -.
DR   HOGENOM; HOG000228064; -.
DR   InParanoid; Q4WDG8; -.
DR   KO; K01693; -.
DR   OMA; ARHGLFD; -.
DR   OrthoDB; 1097523at2759; -.
DR   Proteomes; UP000002530; Chromosome 6.
DR   GO; GO:0004424; F:imidazoleglycerol-phosphate dehydratase activity; IBA:GO_Central.
DR   GO; GO:0000105; P:histidine biosynthetic process; IBA:GO_Central.
DR   CDD; cd07914; IGPD; 1.
DR   Gene3D; 3.30.230.40; -; 1.
DR   HAMAP; MF_00076; HisB; 1.
DR   InterPro; IPR038494; IGPD_sf.
DR   InterPro; IPR000807; ImidazoleglycerolP_deHydtase.
DR   InterPro; IPR020565; ImidazoleglycerP_deHydtase_CS.
DR   InterPro; IPR020568; Ribosomal_S5_D2-typ_fold.
DR   PANTHER; PTHR23133; PTHR23133; 1.
DR   Pfam; PF00475; IGPD; 1.
DR   SUPFAM; SSF54211; SSF54211; 2.
DR   PROSITE; PS00955; IGP_DEHYDRATASE_2; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q4WDG8.
DR   SWISS-2DPAGE; Q4WDG8.
KW   Lyase {ECO:0000313|EMBL:EAL85570.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002530}.
SQ   SEQUENCE   244 AA;  26059 MW;  8D1FD2D406BFFC97 CRC64;
     MPLPARTATV SRVTNETKIQ VSLSLDGGVL PPYEPSDHFP APEDLKEAEA AKHGIVPPKN
     AAHATQFTPT QQITVSTGIG FLDHMLHALA KHSGWSLAIR AKGDLYIDDH HTTEDTFLAL
     GTAFTKALGA RQSLARFGRG DAPLDEALSW AVIDLSSRPW AVINLGFKRE KIGDLSTEMI
     THGLHSFAQA ADVTLHVGCT YGDNDHHRAE SAFKALAVAI RTACTRRVAG EVGAGDVVST
     KGVL
//

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