(data stored in SCRATCH zone)

SWISSPROT: Q4ZZP8_PSEU2

ID   Q4ZZP8_PSEU2            Unreviewed;       419 AA.
AC   Q4ZZP8;
DT   07-JUN-2005, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2005, sequence version 1.
DT   08-MAY-2019, entry version 95.
DE   RecName: Full=Transcription termination factor Rho {ECO:0000256|HAMAP-Rule:MF_01884};
DE            EC=3.6.4.- {ECO:0000256|HAMAP-Rule:MF_01884};
DE   AltName: Full=ATP-dependent helicase Rho {ECO:0000256|HAMAP-Rule:MF_01884};
GN   Name=rho {ECO:0000256|HAMAP-Rule:MF_01884};
GN   OrderedLocusNames=Psyr_0301 {ECO:0000313|EMBL:AAY35374.1};
OS   Pseudomonas syringae pv. syringae (strain B728a).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas; Pseudomonas syringae.
OX   NCBI_TaxID=205918 {ECO:0000313|EMBL:AAY35374.1, ECO:0000313|Proteomes:UP000000426};
RN   [1] {ECO:0000313|EMBL:AAY35374.1, ECO:0000313|Proteomes:UP000000426}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=B728a {ECO:0000313|EMBL:AAY35374.1,
RC   ECO:0000313|Proteomes:UP000000426};
RX   PubMed=16043691; DOI=10.1073/pnas.0504930102;
RA   Feil H., Feil W.S., Chain P., Larimer F., Dibartolo G., Copeland A.,
RA   Lykidis A., Trong S., Nolan M., Goltsman E., Thiel J., Malfatti S.,
RA   Loper J.E., Lapidus A., Detter J.C., Land M., Richardson P.M.,
RA   Kyrpides N.C., Ivanova N., Lindow S.E.;
RT   "Comparison of the complete genome sequences of Pseudomonas syringae
RT   pv. syringae B728a and pv. tomato DC3000.";
RL   Proc. Natl. Acad. Sci. U.S.A. 102:11064-11069(2005).
CC   -!- FUNCTION: Facilitates transcription termination by a mechanism
CC       that involves Rho binding to the nascent RNA, activation of Rho's
CC       RNA-dependent ATPase activity, and release of the mRNA from the
CC       DNA template. {ECO:0000256|HAMAP-Rule:MF_01884}.
CC   -!- SUBUNIT: Homohexamer. The homohexamer assembles into an open ring
CC       structure. {ECO:0000256|HAMAP-Rule:MF_01884}.
CC   -!- SIMILARITY: Belongs to the Rho family. {ECO:0000256|HAMAP-
CC       Rule:MF_01884}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; CP000075; AAY35374.1; -; Genomic_DNA.
DR   RefSeq; WP_002551560.1; NC_007005.1.
DR   RefSeq; YP_233412.1; NC_007005.1.
DR   STRING; 205918.Psyr_0301; -.
DR   EnsemblBacteria; AAY35374; AAY35374; Psyr_0301.
DR   GeneID; 3365777; -.
DR   KEGG; psb:Psyr_0301; -.
DR   PATRIC; fig|205918.7.peg.303; -.
DR   eggNOG; ENOG4105C4P; Bacteria.
DR   eggNOG; COG1158; LUCA.
DR   HOGENOM; HOG000076952; -.
DR   KO; K03628; -.
DR   OMA; DYNYLPG; -.
DR   BioCyc; PSYR205918:G1G4J-302-MONOMER; -.
DR   Proteomes; UP000000426; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0008186; F:RNA-dependent ATPase activity; IEA:InterPro.
DR   GO; GO:0006353; P:DNA-templated transcription, termination; IEA:UniProtKB-UniRule.
DR   CDD; cd04459; Rho_CSD; 1.
DR   CDD; cd01128; rho_factor; 1.
DR   HAMAP; MF_01884; Rho; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR000194; ATPase_F1/V1/A1_a/bsu_nucl-bd.
DR   InterPro; IPR011129; CSD.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR041703; Rho_factor_ATP-bd.
DR   InterPro; IPR011112; Rho_N.
DR   InterPro; IPR036269; Rho_N_sf.
DR   InterPro; IPR011113; Rho_RNA-bd.
DR   InterPro; IPR004665; Term_rho.
DR   PANTHER; PTHR46425; PTHR46425; 1.
DR   Pfam; PF00006; ATP-synt_ab; 1.
DR   Pfam; PF07498; Rho_N; 1.
DR   Pfam; PF07497; Rho_RNA_bind; 1.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00357; CSP; 1.
DR   SMART; SM00959; Rho_N; 1.
DR   SUPFAM; SSF50249; SSF50249; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   SUPFAM; SSF68912; SSF68912; 1.
DR   TIGRFAMs; TIGR00767; rho; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q4ZZP8.
DR   SWISS-2DPAGE; Q4ZZP8.
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_01884};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000426};
KW   Helicase {ECO:0000256|HAMAP-Rule:MF_01884};
KW   Hydrolase {ECO:0000256|HAMAP-Rule:MF_01884,
KW   ECO:0000256|SAAS:SAAS00446781};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_01884};
KW   RNA-binding {ECO:0000256|HAMAP-Rule:MF_01884};
KW   Transcription {ECO:0000256|HAMAP-Rule:MF_01884};
KW   Transcription regulation {ECO:0000256|HAMAP-Rule:MF_01884};
KW   Transcription termination {ECO:0000256|HAMAP-Rule:MF_01884}.
FT   DOMAIN        5     47       Rho_N. {ECO:0000259|SMART:SM00959}.
FT   DOMAIN       52    118       CSP. {ECO:0000259|SMART:SM00357}.
FT   DOMAIN      170    355       AAA. {ECO:0000259|SMART:SM00382}.
FT   NP_BIND     169    174       ATP. {ECO:0000256|HAMAP-Rule:MF_01884}.
FT   NP_BIND     181    186       ATP. {ECO:0000256|HAMAP-Rule:MF_01884}.
FT   REGION       61     66       RNA-binding 1. {ECO:0000256|HAMAP-Rule:
FT                                MF_01884}.
FT   REGION       78     80       RNA-binding 1. {ECO:0000256|HAMAP-Rule:
FT                                MF_01884}.
FT   REGION      108    110       RNA-binding 1. {ECO:0000256|HAMAP-Rule:
FT                                MF_01884}.
FT   REGION      284    288       RNA-binding 2. {ECO:0000256|HAMAP-Rule:
FT                                MF_01884}.
FT   BINDING     212    212       ATP. {ECO:0000256|HAMAP-Rule:MF_01884}.
FT   SITE        326    326       RNA-binding 2. {ECO:0000256|HAMAP-Rule:
FT                                MF_01884}.
SQ   SEQUENCE   419 AA;  47029 MW;  131CCEDF92D47FC2 CRC64;
     MNLTELKQKP ITELLEMAEQ AGIENMARSR KQDVIFSLLK RHAKSGEEIS GDGVLEILQD
     GFGFLRSADA SYLAGPDDIY VSPSQIRRFN LRTGDTIVGK IRPPKEGERY FALLKVDTIN
     YDRPENAKNK ILFENLTPLF PTIRMKMEAG NGSTEDLTGR VIDLCAPIGK GQRGLIVAPP
     KAGKTIMLQN IASNITRNNP EVHLIVLLID ERPEEVTEMQ RTVRGEVVAS TFDEPPTRHV
     QVAEMVIEKA KRLVEHKKDV VILLDSITRL ARAYNTVIPS SGKVLTGGVD AHALEKPKRF
     FGAARNIEEG GSLTIIATAL VETGSKMDEV IYEEFKGTGN MELPLDRKIA EKRVFPAINI
     NRSGTRREEL LTADDELQRM WILRKLLHPM DEVAAIEFLI DKLKQTKTND EFFLSMKRK
//

If you have problems or comments...

PBIL Back to PBIL home page