(data stored in ACNUC11299 zone)

SWISSPROT: Q5CUJ2_CRYPI

ID   Q5CUJ2_CRYPI            Unreviewed;      1902 AA.
AC   Q5CUJ2;
DT   12-APR-2005, integrated into UniProtKB/TrEMBL.
DT   12-APR-2005, sequence version 1.
DT   07-JUN-2017, entry version 66.
DE   RecName: Full=DNA-directed RNA polymerase subunit {ECO:0000256|RuleBase:RU004279};
DE            EC=2.7.7.6 {ECO:0000256|RuleBase:RU004279};
DE   Flags: Fragment;
GN   ORFNames=cgd3_2620 {ECO:0000313|EMBL:EAK89262.1};
OS   Cryptosporidium parvum (strain Iowa II).
OC   Eukaryota; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC   Eucoccidiorida; Eimeriorina; Cryptosporidiidae; Cryptosporidium.
OX   NCBI_TaxID=353152 {ECO:0000313|EMBL:EAK89262.1, ECO:0000313|Proteomes:UP000006726};
RN   [1] {ECO:0000313|EMBL:EAK89262.1, ECO:0000313|Proteomes:UP000006726}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Iowa II {ECO:0000313|Proteomes:UP000006726};
RX   PubMed=15044751; DOI=10.1126/science.1094786;
RA   Abrahamsen M.S., Templeton T.J., Enomoto S., Abrahante J.E., Zhu G.,
RA   Lancto C.A., Deng M., Liu C., Widmer G., Tzipori S., Buck G.A., Xu P.,
RA   Bankier A.T., Dear P.H., Konfortov B.A., Spriggs H.F., Iyer L.,
RA   Anantharaman V., Aravind L., Kapur V.;
RT   "Complete genome sequence of the apicomplexan, Cryptosporidium
RT   parvum.";
RL   Science 304:441-445(2004).
CC   -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription
CC       of DNA into RNA using the four ribonucleoside triphosphates as
CC       substrates. {ECO:0000256|RuleBase:RU004279}.
CC   -!- CATALYTIC ACTIVITY: Nucleoside triphosphate + RNA(n) = diphosphate
CC       + RNA(n+1). {ECO:0000256|RuleBase:RU004279}.
CC   -!- SIMILARITY: Belongs to the RNA polymerase beta' chain family.
CC       {ECO:0000256|RuleBase:RU004279}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:EAK89262.1}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; AAEE01000004; EAK89262.1; -; Genomic_DNA.
DR   RefSeq; XP_626822.1; XM_626822.1.
DR   ProteinModelPortal; Q5CUJ2; -.
DR   STRING; 353152.XP_626822.1; -.
DR   EnsemblProtists; EAK89262; EAK89262; cgd3_2620.
DR   GeneID; 3373777; -.
DR   KEGG; cpv:cgd3_2620; -.
DR   EuPathDB; CryptoDB:cgd3_2620; -.
DR   eggNOG; KOG0260; Eukaryota.
DR   eggNOG; COG0086; LUCA.
DR   HOGENOM; HOG000222975; -.
DR   InParanoid; Q5CUJ2; -.
DR   KO; K03006; -.
DR   OMA; MPDFDPT; -.
DR   Proteomes; UP000006726; Chromosome 3.
DR   GO; GO:0005665; C:DNA-directed RNA polymerase II, core complex; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IEA:InterPro.
DR   InterPro; IPR000722; RNA_pol_asu.
DR   InterPro; IPR000684; RNA_pol_II_repeat_euk.
DR   InterPro; IPR006592; RNA_pol_N.
DR   InterPro; IPR007080; RNA_pol_Rpb1_1.
DR   InterPro; IPR007066; RNA_pol_Rpb1_3.
DR   InterPro; IPR007083; RNA_pol_Rpb1_4.
DR   InterPro; IPR007081; RNA_pol_Rpb1_5.
DR   InterPro; IPR007075; RNA_pol_Rpb1_6.
DR   InterPro; IPR007073; RNA_pol_Rpb1_7.
DR   Pfam; PF04997; RNA_pol_Rpb1_1; 1.
DR   Pfam; PF00623; RNA_pol_Rpb1_2; 1.
DR   Pfam; PF04983; RNA_pol_Rpb1_3; 1.
DR   Pfam; PF05000; RNA_pol_Rpb1_4; 1.
DR   Pfam; PF04998; RNA_pol_Rpb1_5; 1.
DR   Pfam; PF04992; RNA_pol_Rpb1_6; 1.
DR   Pfam; PF04990; RNA_pol_Rpb1_7; 1.
DR   Pfam; PF05001; RNA_pol_Rpb1_R; 19.
DR   SMART; SM00663; RPOLA_N; 1.
DR   PROSITE; PS00115; RNA_POL_II_REPEAT; 3.
PE   3: Inferred from homology;
DR   PRODOM; Q5CUJ2.
DR   SWISS-2DPAGE; Q5CUJ2.
KW   Complete proteome {ECO:0000313|Proteomes:UP000006726};
KW   DNA-directed RNA polymerase {ECO:0000256|RuleBase:RU004279,
KW   ECO:0000313|EMBL:EAK89262.1};
KW   Nucleotidyltransferase {ECO:0000256|RuleBase:RU004279};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006726};
KW   Transcription {ECO:0000256|RuleBase:RU004279};
KW   Transferase {ECO:0000256|RuleBase:RU004279}.
FT   DOMAIN      234    538       RPOLA_N. {ECO:0000259|SMART:SM00663}.
FT   NON_TER       1      1       {ECO:0000313|EMBL:EAK89262.1}.
SQ   SEQUENCE   1902 AA;  213171 MW;  DE0ED93F88897DA0 CRC64;
     RRIIQEIMST ALELNSPFSS KELKRVFSIE FGVLSPELIR KYSVLEIKVS DIYENGRPKS
     GGLNDPLLGT TDYHILCETC HMDIKTCPGH FAHIELGKPM FHIGFITTVL KLLRCVCYAC
     SKLFVDTLDP KFKQIKRIKN PRLRLKKILE MRSSSSRCII SSDGSGCGFV QPTYSKEGYN
     LYINQNQDEN RIIDDESVDS KRLLAAEEVL TIFKRISHDD MKILGFDPVK CNPSWFINTV
     IPIPPPAVRP YVQFGSDRSE DDLTLKLQQI IKLNENLKKQ IRIGSPEHII SEMSTVLQYH
     LITLINNDLP GLPQSRTRSN RPIKSLRARL KGKDGRIRGN LMGKRVDFSA RTVITGDPNL
     AVDQVGVPYS IAMTLTYPEV VTPYNIEELK ELVQRGPHEW PGATSIIQED GTKVDLRFSN
     TSNNSNNILQ YGWKVERHMK NDDLVLFNRQ PSLHKMSIMG HRVKILPYST FRLNLSVTSP
     YNADFDGDEM NLHLAQSHET RSEIKNLMMV PRQIVSPQGN KPVIGIVQDS LLGIFLLTRK
     STFLTRDKFL QLLLCIPYWN GNIPPPAILR PQPLWTGKQI ITVLLAFTTD LGEPIELNLM
     RDGSIVSIKQ SNNSSNTDKD DSKEAIVNNP WISELDNQVI IQKGEHICGV LTKKIAGSSS
     GSLIHILWNE IGPEKTGLFL TYTQMVVNTW LLEHGFTVGC QDIQPQNYTL EKIMNSLEGS
     KLQVQQIIRR AQKGKLDCQP GKSLIESFEA QVNQELNSAR ELSGTIATEN LDSSKNNIVA
     MVQCGSKGST INISQIMACV GQQNVEGKRI PFGFRDRSLP HFLKYDYGPE SRGFVSNSYL
     SGLTPQEVFF HAMGGREGII DTACKTSETG YIQRRLIKAM EDCMVQYDRT VRNSNGDIIQ
     FLYGEDGMAG EFIEDQVIEL LQMEAAVFQH KYRHNLEHPR WGSSWAGVQP SLIKNLQFDL
     ESQNILNSEY KQLVTDREQL GKDIFPDGET RQHLPININR IIQMAQQKFP QRVSDTSSSK
     DWGPVYIIKK VESLLDKLLL WKNVGIINDE GNKSNFVFDS IIAEVQKNAT TLLGIHIRSS
     LASKKILEVD RLGPTAFEWI LGEIEHQFYR SLAHSGEMVG TIAAQSIGEP ATQMTLNTFH
     FAGVGSKNVT LGVPRLRELI NVAKNVRTPT LTVYLESGIA NDQEQAKDVL TLLEHTMLQN
     ITTIAHILYD PEQDKTIVEA DKSWVSDYYE FPDDADITSR LGTWLLRIQL NNKLVTDKKL
     SMKEIGDKIL MEFSKDELDC IWTDDNSDEL VLRLRIKNIE PTNNIRDNIH SSEENDSISP
     SITSGVEEHK FLEKLMTECL SQITLRGINN IKKVYMKEEQ VSRYDSVSQK MVRDNQWVLD
     TDGCNLEAVL CHTAIDSTRT ISNDITEVFS VLGIEAVRRA LLRELRTVIS FDGSYVNYRH
     LALLCDNMTQ KGHLMSITRH GINRVDKGPL QKCSFEETVE VLMDAAMFGE TDYLNGVSEN
     VMLGQLAPYG TACFDVLIDP DKLRDTATHL EIHGEFAKLG KFSTLSQTTR SYSDSGAFES
     DSFESPMSPL SPMSPLYQSY EPMSPMISGQ FSPVQMTPRS PMSPVSPGGI FSPVPYSPMS
     PSSPLMDYTP TSPIYAASSP TYNTEVSERA RKKYKVNNTL SSYSPSSPLN SDNKISNISP
     DLSPTSPHYS PTSPHYSPTS PHYSPTSPHY SPTSPHYSPT SPHYSPTSPH YSPTSPHYSP
     TSPHYSPTSP HYSPTSPHYS PTSPHYSPTS PHYSPTSPHY SPTSPHYSPT SPHYSPSSPH
     YSPTSPQYSP TSPNYNPASP NYSPTSHYSP TSPNYNPTSP NYSPSSPNYI SNNSGSPGYS
     PSSPQYDPIA VASVPRSPSY SVGKMVDAEY SPSSPLDETK NS
//

If you have problems or comments...

PBIL Back to PBIL home page