(data stored in ACNUC3476 zone)

SWISSPROT: Q5KHL0_CRYNJ

ID   Q5KHL0_CRYNJ            Unreviewed;       819 AA.
AC   Q5KHL0; Q55US9;
DT   15-FEB-2005, integrated into UniProtKB/TrEMBL.
DT   15-FEB-2005, sequence version 1.
DT   11-DEC-2019, entry version 85.
DE   RecName: Full=Aa_trans domain-containing protein {ECO:0000259|Pfam:PF01490};
GN   OrderedLocusNames=CND06100 {ECO:0000313|EMBL:AAW43218.1};
OS   Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC
OS   MYA-565) (Filobasidiella neoformans).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC   Tremellales; Cryptococcaceae; Cryptococcus;
OC   Cryptococcus neoformans species complex.
OX   NCBI_TaxID=214684 {ECO:0000313|EMBL:AAW43218.1, ECO:0000313|Proteomes:UP000002149};
RN   [1] {ECO:0000313|EMBL:AAW43218.1, ECO:0000313|Proteomes:UP000002149}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JEC21 / ATCC MYA-565 {ECO:0000313|Proteomes:UP000002149};
RX   PubMed=15653466; DOI=10.1126/science.1103773;
RA   Loftus B.J., Fung E., Roncaglia P., Rowley D., Amedeo P., Bruno D.,
RA   Vamathevan J., Miranda M., Anderson I.J., Fraser J.A., Allen J.E.,
RA   Bosdet I.E., Brent M.R., Chiu R., Doering T.L., Donlin M.J., D'Souza C.A.,
RA   Fox D.S., Grinberg V., Fu J., Fukushima M., Haas B.J., Huang J.C.,
RA   Janbon G., Jones S.J.M., Koo H.L., Krzywinski M.I., Kwon-Chung K.J.,
RA   Lengeler K.B., Maiti R., Marra M.A., Marra R.E., Mathewson C.A.,
RA   Mitchell T.G., Pertea M., Riggs F.R., Salzberg S.L., Schein J.E.,
RA   Shvartsbeyn A., Shin H., Shumway M., Specht C.A., Suh B.B., Tenney A.,
RA   Utterback T.R., Wickes B.L., Wortman J.R., Wye N.H., Kronstad J.W.,
RA   Lodge J.K., Heitman J., Davis R.W., Fraser C.M., Hyman R.W.;
RT   "The genome of the basidiomycetous yeast and human pathogen Cryptococcus
RT   neoformans.";
RL   Science 307:1321-1324(2005).
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DR   EMBL; AE017344; AAW43218.1; -; Genomic_DNA.
DR   RefSeq; XP_570525.1; XM_570525.1.
DR   STRING; 5207.AAW43218; -.
DR   PaxDb; Q5KHL0; -.
DR   EnsemblFungi; AAW43218; AAW43218; CND06100.
DR   GeneID; 3256943; -.
DR   KEGG; cne:CND06100; -.
DR   EuPathDB; FungiDB:CND06100; -.
DR   eggNOG; KOG1304; Eukaryota.
DR   eggNOG; COG0814; LUCA.
DR   HOGENOM; HOG000185918; -.
DR   InParanoid; Q5KHL0; -.
DR   KO; K14209; -.
DR   OMA; LYGKHMR; -.
DR   OrthoDB; 464614at2759; -.
DR   Proteomes; UP000002149; Chromosome 4.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015171; F:amino acid transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0003333; P:amino acid transmembrane transport; IBA:GO_Central.
DR   InterPro; IPR013057; AA_transpt_TM.
DR   Pfam; PF01490; Aa_trans; 1.
PE   4: Predicted;
DR   PRODOM; Q5KHL0.
DR   SWISS-2DPAGE; Q5KHL0.
KW   Membrane {ECO:0000256|SAAS:SAAS00051334, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002149};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00442872, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00442834,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        453..476
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        497..519
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        525..549
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        561..581
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        601..624
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        636..659
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        679..704
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        725..742
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        748..769
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        781..799
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          420..801
FT                   /note="Aa_trans"
FT                   /evidence="ECO:0000259|Pfam:PF01490"
FT   REGION          1..255
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          354..394
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        10..68
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        102..162
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        182..201
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        206..221
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   819 AA;  87752 MW;  514AD198232758B1 CRC64;
     MPPKQPPKKS STPSMSGAEP NINSNGNTVK PRSISISRNS PSTNSGGTPP VPNIPSRASM
     SSTGPPRSFA GSFRPASSVV GMENSKSRRQ SISKEKIISK DSSDSLIGNK TIPQTQTTSS
     ALTAALESPQ PQGLSHQGSG SLSRPPISRD DSGTSALRNG AASTSAPKDG DKAGESSFSN
     LADVPDEEKA RVLRRHLVSA DERGASSPTP GGQSPAGSGI NMGGTPTRAE FDDILGESGV
     SGYGSIDAHP KDDSDQFPIP YDAPGGDVTH DLYKWQHDHR TRPVRSASFS HVPVDRSTIL
     DPHLAHIKEP GGFRRNFVVN RAQEQGLEAP DMVRNVVDFL FLYGHFAGED LNEDEDVLEE
     DEESYPEDAS SSSAYARRPF PAGGEEAGQI ARGERAPLLG STKRSLSRHR RTKSGHNQGT
     ASVTQAVLML LKGFVGTGIL FMGKAFFNGG ILFSSIVMLA IAGISLWSFL LLVQAYMKVP
     GSFGDIGGEL YGNNMRLIIL TSITVSQIGF VAAYSIFIAE NLQAFIMAVS NCRTFIPVKY
     LIFAQLIVFM PLSMIRNLAK LSGTALIADA FILIGIIYIG GNEISVLSKN GVADVALFNK
     QSFPLLIGTA VFAFEGIGLV IPITESMREP QKFPRVLSGV MFCVAILFAG SGVMSYAAYG
     SDIQTVVIVN LPQDDKFVQA VQFLYSVAIL LSSPLQLFPA VRIMENGLFS KSGKHNPSVK
     WQKNVFRSCT VIFCSLLSWA GSNELDKFVA LIGSFACIPL CFIYPPMLHL KACARTPKAR
     IMDWTLIVFG TIVGAFTTVQ TLRSLFIPSA EGPKFGGCE
//

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