(data stored in SCRATCH zone)

SWISSPROT: Q5LWH7_RUEPO

ID   Q5LWH7_RUEPO            Unreviewed;       326 AA.
AC   Q5LWH7;
DT   01-FEB-2005, integrated into UniProtKB/TrEMBL.
DT   01-FEB-2005, sequence version 1.
DT   08-MAY-2019, entry version 89.
DE   RecName: Full=33 kDa chaperonin {ECO:0000256|SAAS:SAAS01084522};
GN   Name=hslO {ECO:0000313|EMBL:AAV93355.1};
GN   OrderedLocusNames=SPO0024 {ECO:0000313|EMBL:AAV93355.1};
OS   Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3)
OS   (Silicibacter pomeroyi).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodobacterales;
OC   Rhodobacteraceae; Ruegeria.
OX   NCBI_TaxID=246200 {ECO:0000313|EMBL:AAV93355.1, ECO:0000313|Proteomes:UP000001023};
RN   [1] {ECO:0000313|EMBL:AAV93355.1, ECO:0000313|Proteomes:UP000001023}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700808 / DSM 15171 / DSS-3
RC   {ECO:0000313|Proteomes:UP000001023};
RX   PubMed=15602564; DOI=10.1038/nature03170;
RA   Moran M.A., Buchan A., Gonzalez J.M., Heidelberg J.F., Whitman W.B.,
RA   Kiene R.P., Henriksen J.R., King G.M., Belas R., Fuqua C., Brinkac L.,
RA   Lewis M., Johri S., Weaver B., Pai G., Eisen J.A., Rahe E.,
RA   Sheldon W.M., Ye W., Miller T.R., Carlton J., Rasko D.A.,
RA   Paulsen I.T., Ren Q., Daugherty S.C., Deboy R.T., Dodson R.J.,
RA   Durkin A.S., Madupu R., Nelson W.C., Sullivan S.A., Rosovitz M.J.,
RA   Haft D.H., Selengut J., Ward N.;
RT   "Genome sequence of Silicibacter pomeroyi reveals adaptations to the
RT   marine environment.";
RL   Nature 432:910-913(2004).
RN   [2] {ECO:0000313|EMBL:AAV93355.1, ECO:0000313|Proteomes:UP000001023}
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 700808 / DSM 15171 / DSS-3
RC   {ECO:0000313|Proteomes:UP000001023};
RX   PubMed=25780504; DOI=10.1186/1944-3277-9-11;
RA   Rivers A.R., Smith C.B., Moran M.A.;
RT   "An updated genome annotation for the model marine bacterium Ruegeria
RT   pomeroyi DSS-3.";
RL   Stand. Genomic Sci. 9:11-11(2014).
CC   -!- FUNCTION: Redox regulated molecular chaperone. Protects both
CC       thermally unfolding and oxidatively damaged proteins from
CC       irreversible aggregation. Plays an important role in the bacterial
CC       defense system toward oxidative stress.
CC       {ECO:0000256|SAAS:SAAS01084509}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|SAAS:SAAS01084524}.
CC   -!- SIMILARITY: Belongs to the HSP33 family.
CC       {ECO:0000256|SAAS:SAAS01084516}.
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DR   EMBL; CP000031; AAV93355.1; -; Genomic_DNA.
DR   RefSeq; WP_011045796.1; NC_003911.12.
DR   STRING; 246200.SPO0024; -.
DR   EnsemblBacteria; AAV93355; AAV93355; SPO0024.
DR   KEGG; sil:SPO0024; -.
DR   eggNOG; ENOG4105F4C; Bacteria.
DR   eggNOG; COG1281; LUCA.
DR   HOGENOM; HOG000261999; -.
DR   KO; K04083; -.
DR   OMA; DMQCECC; -.
DR   OrthoDB; 1406579at2; -.
DR   BioCyc; RPOM246200:G1G48-24-MONOMER; -.
DR   Proteomes; UP000001023; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:InterPro.
DR   GO; GO:0006457; P:protein folding; IEA:InterPro.
DR   CDD; cd00498; Hsp33; 1.
DR   Gene3D; 1.10.287.480; -; 1.
DR   Gene3D; 3.55.30.10; -; 1.
DR   Gene3D; 3.90.1280.10; -; 1.
DR   InterPro; IPR000397; Heat_shock_Hsp33.
DR   InterPro; IPR016154; Heat_shock_Hsp33_C.
DR   InterPro; IPR016153; Heat_shock_Hsp33_N.
DR   InterPro; IPR023212; Hsp33_helix_hairpin_bin_dom_sf.
DR   PANTHER; PTHR30111; PTHR30111; 1.
DR   Pfam; PF01430; HSP33; 1.
DR   PIRSF; PIRSF005261; Heat_shock_Hsp33; 1.
DR   SUPFAM; SSF118352; SSF118352; 1.
DR   SUPFAM; SSF64397; SSF64397; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q5LWH7.
DR   SWISS-2DPAGE; Q5LWH7.
KW   Chaperone {ECO:0000256|SAAS:SAAS01084514};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001023};
KW   Cytoplasm {ECO:0000256|SAAS:SAAS01084515};
KW   Disulfide bond {ECO:0000256|SAAS:SAAS01084518};
KW   Redox-active center {ECO:0000256|SAAS:SAAS01084519};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001023};
KW   Zinc {ECO:0000256|SAAS:SAAS01084517}.
SQ   SEQUENCE   326 AA;  35305 MW;  B80F750141AFF5FF CRC64;
     MTLGTKIAWD DTVLPFQLDL PDMRGRVARL DGVLDGILKQ HDYPTVVEAL VAEMALLTAL
     IGQTIGLRWK LSLQVQSKGA VRMIATDYYA PRAEGEPARI RAYAGFDADR LTDGAPFDQV
     GEGYFAILID QGKGTQPYQG ITPLAGGSLS ACAEAYFAQS EQLPTRFQLR FGKSTEPGVP
     EHWRAGGVML QHMPKASPFA AGGPGTGDIL TAADLVDGAE GENWNRVNIL LDTVEDLELI
     GPALPPTDLL VRLFHEEQPR VYDAQSVRFG CTCSEERVRQ SLSIYSVKDI GHMTTDEGTV
     TADCQFCGAH YVLDPASVGF EADQGD
//

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