(data stored in SCRATCH zone)

SWISSPROT: Q5LWU3_RUEPO

ID   Q5LWU3_RUEPO            Unreviewed;       391 AA.
AC   Q5LWU3;
DT   01-FEB-2005, integrated into UniProtKB/TrEMBL.
DT   01-FEB-2005, sequence version 1.
DT   08-MAY-2019, entry version 89.
DE   SubName: Full=Beta-ketothiolase {ECO:0000313|EMBL:AAV93470.1};
GN   Name=bktB {ECO:0000313|EMBL:AAV93470.1};
GN   OrderedLocusNames=SPO0142 {ECO:0000313|EMBL:AAV93470.1};
OS   Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3)
OS   (Silicibacter pomeroyi).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodobacterales;
OC   Rhodobacteraceae; Ruegeria.
OX   NCBI_TaxID=246200 {ECO:0000313|EMBL:AAV93470.1, ECO:0000313|Proteomes:UP000001023};
RN   [1] {ECO:0000313|EMBL:AAV93470.1, ECO:0000313|Proteomes:UP000001023}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700808 / DSM 15171 / DSS-3
RC   {ECO:0000313|Proteomes:UP000001023};
RX   PubMed=15602564; DOI=10.1038/nature03170;
RA   Moran M.A., Buchan A., Gonzalez J.M., Heidelberg J.F., Whitman W.B.,
RA   Kiene R.P., Henriksen J.R., King G.M., Belas R., Fuqua C., Brinkac L.,
RA   Lewis M., Johri S., Weaver B., Pai G., Eisen J.A., Rahe E.,
RA   Sheldon W.M., Ye W., Miller T.R., Carlton J., Rasko D.A.,
RA   Paulsen I.T., Ren Q., Daugherty S.C., Deboy R.T., Dodson R.J.,
RA   Durkin A.S., Madupu R., Nelson W.C., Sullivan S.A., Rosovitz M.J.,
RA   Haft D.H., Selengut J., Ward N.;
RT   "Genome sequence of Silicibacter pomeroyi reveals adaptations to the
RT   marine environment.";
RL   Nature 432:910-913(2004).
RN   [2] {ECO:0000313|EMBL:AAV93470.1, ECO:0000313|Proteomes:UP000001023}
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 700808 / DSM 15171 / DSS-3
RC   {ECO:0000313|Proteomes:UP000001023};
RX   PubMed=25780504; DOI=10.1186/1944-3277-9-11;
RA   Rivers A.R., Smith C.B., Moran M.A.;
RT   "An updated genome annotation for the model marine bacterium Ruegeria
RT   pomeroyi DSS-3.";
RL   Stand. Genomic Sci. 9:11-11(2014).
CC   -!- SIMILARITY: Belongs to the thiolase family.
CC       {ECO:0000256|RuleBase:RU003557}.
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DR   EMBL; CP000031; AAV93470.1; -; Genomic_DNA.
DR   RefSeq; WP_011045913.1; NC_003911.12.
DR   STRING; 246200.SPO0142; -.
DR   EnsemblBacteria; AAV93470; AAV93470; SPO0142.
DR   KEGG; sil:SPO0142; -.
DR   eggNOG; ENOG4105CHU; Bacteria.
DR   eggNOG; COG0183; LUCA.
DR   HOGENOM; HOG000012238; -.
DR   KO; K00626; -.
DR   OMA; MNVNRLC; -.
DR   OrthoDB; 1058688at2; -.
DR   BioCyc; RPOM246200:G1G48-146-MONOMER; -.
DR   Proteomes; UP000001023; Chromosome.
DR   GO; GO:0016747; F:transferase activity, transferring acyl groups other than amino-acyl groups; IEA:InterPro.
DR   GO; GO:0006112; P:energy reserve metabolic process; ISS:TIGR.
DR   CDD; cd00751; thiolase; 1.
DR   Gene3D; 3.40.47.10; -; 2.
DR   InterPro; IPR002155; Thiolase.
DR   InterPro; IPR016039; Thiolase-like.
DR   InterPro; IPR020610; Thiolase_AS.
DR   InterPro; IPR020617; Thiolase_C.
DR   InterPro; IPR020613; Thiolase_CS.
DR   InterPro; IPR020616; Thiolase_N.
DR   Pfam; PF02803; Thiolase_C; 1.
DR   Pfam; PF00108; Thiolase_N; 1.
DR   PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR   SUPFAM; SSF53901; SSF53901; 2.
DR   TIGRFAMs; TIGR01930; AcCoA-C-Actrans; 1.
DR   PROSITE; PS00737; THIOLASE_2; 1.
DR   PROSITE; PS00099; THIOLASE_3; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q5LWU3.
DR   SWISS-2DPAGE; Q5LWU3.
KW   Acyltransferase {ECO:0000256|RuleBase:RU003557};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001023};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001023};
KW   Transferase {ECO:0000256|RuleBase:RU003557}.
FT   DOMAIN        4    260       Thiolase_N. {ECO:0000259|Pfam:PF00108}.
FT   DOMAIN      268    389       Thiolase_C. {ECO:0000259|Pfam:PF02803}.
FT   ACT_SITE     89     89       Acyl-thioester intermediate.
FT                                {ECO:0000256|PIRSR:PIRSR000429-1}.
FT   ACT_SITE    347    347       Proton acceptor. {ECO:0000256|PIRSR:
FT                                PIRSR000429-1}.
FT   ACT_SITE    377    377       Proton acceptor. {ECO:0000256|PIRSR:
FT                                PIRSR000429-1}.
SQ   SEQUENCE   391 AA;  40064 MW;  DCF36194683DDB7D CRC64;
     MTDIVILDGA RTAIGTFGGA LASTAPIDLA TVVTEAALER SGVEGGQIGH VVFGHVINTE
     PRDMYLSRVA AMQAGIPNGT PAMNVNRLCG SGAQAIVSAV QSLMLGDAEF AVAGGAESMS
     RSPFIMTQAR WGAKMGDVKS LDMMLGALNC PFGTGHMGVT AENVADEHQI SREQMDQFAM
     TSQERAAAAI AAGHFDGQIT PVQVKVKRDM VDFKVDEHPK ATSVEVLAGL KPVFKKDGRV
     TAGNASGIND GAAAMVLATA DAAEKAGLKP KARILGYAHA GVRPEVMGIG PVPAVQNLLA
     RTGLSIGDFD VIESNEAFAA QALAVNKELG LDAAKVNPNG GAIALGHPVG ATGAIITLKT
     LYELERTGGS KGLITMCIGG GQGIAIAIEL L
//

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