(data stored in SCRATCH zone)

SWISSPROT: Q5LXA8_RUEPO

ID   Q5LXA8_RUEPO            Unreviewed;       391 AA.
AC   Q5LXA8;
DT   01-FEB-2005, integrated into UniProtKB/TrEMBL.
DT   01-FEB-2005, sequence version 1.
DT   08-MAY-2019, entry version 87.
DE   SubName: Full=Acetyl-CoA acetyltransferase {ECO:0000313|EMBL:AAV93644.1};
DE            EC=2.3.1.9 {ECO:0000313|EMBL:AAV93644.1};
GN   Name=phbA {ECO:0000313|EMBL:AAV93644.1};
GN   OrderedLocusNames=SPO0326 {ECO:0000313|EMBL:AAV93644.1};
OS   Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3)
OS   (Silicibacter pomeroyi).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodobacterales;
OC   Rhodobacteraceae; Ruegeria.
OX   NCBI_TaxID=246200 {ECO:0000313|EMBL:AAV93644.1, ECO:0000313|Proteomes:UP000001023};
RN   [1] {ECO:0000313|EMBL:AAV93644.1, ECO:0000313|Proteomes:UP000001023}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700808 / DSM 15171 / DSS-3
RC   {ECO:0000313|Proteomes:UP000001023};
RX   PubMed=15602564; DOI=10.1038/nature03170;
RA   Moran M.A., Buchan A., Gonzalez J.M., Heidelberg J.F., Whitman W.B.,
RA   Kiene R.P., Henriksen J.R., King G.M., Belas R., Fuqua C., Brinkac L.,
RA   Lewis M., Johri S., Weaver B., Pai G., Eisen J.A., Rahe E.,
RA   Sheldon W.M., Ye W., Miller T.R., Carlton J., Rasko D.A.,
RA   Paulsen I.T., Ren Q., Daugherty S.C., Deboy R.T., Dodson R.J.,
RA   Durkin A.S., Madupu R., Nelson W.C., Sullivan S.A., Rosovitz M.J.,
RA   Haft D.H., Selengut J., Ward N.;
RT   "Genome sequence of Silicibacter pomeroyi reveals adaptations to the
RT   marine environment.";
RL   Nature 432:910-913(2004).
RN   [2] {ECO:0000313|EMBL:AAV93644.1, ECO:0000313|Proteomes:UP000001023}
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 700808 / DSM 15171 / DSS-3
RC   {ECO:0000313|Proteomes:UP000001023};
RX   PubMed=25780504; DOI=10.1186/1944-3277-9-11;
RA   Rivers A.R., Smith C.B., Moran M.A.;
RT   "An updated genome annotation for the model marine bacterium Ruegeria
RT   pomeroyi DSS-3.";
RL   Stand. Genomic Sci. 9:11-11(2014).
CC   -!- SIMILARITY: Belongs to the thiolase family.
CC       {ECO:0000256|RuleBase:RU003557}.
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DR   EMBL; CP000031; AAV93644.1; -; Genomic_DNA.
DR   RefSeq; WP_011046087.1; NC_003911.12.
DR   STRING; 246200.SPO0326; -.
DR   EnsemblBacteria; AAV93644; AAV93644; SPO0326.
DR   KEGG; sil:SPO0326; -.
DR   eggNOG; ENOG4105CHU; Bacteria.
DR   eggNOG; COG0183; LUCA.
DR   HOGENOM; HOG000012238; -.
DR   KO; K00626; -.
DR   OMA; WDVYNKF; -.
DR   OrthoDB; 1058688at2; -.
DR   BioCyc; RPOM246200:G1G48-333-MONOMER; -.
DR   Proteomes; UP000001023; Chromosome.
DR   GO; GO:0003985; F:acetyl-CoA C-acetyltransferase activity; ISS:TIGR.
DR   GO; GO:0006112; P:energy reserve metabolic process; ISS:TIGR.
DR   CDD; cd00751; thiolase; 1.
DR   Gene3D; 3.40.47.10; -; 2.
DR   InterPro; IPR002155; Thiolase.
DR   InterPro; IPR016039; Thiolase-like.
DR   InterPro; IPR020615; Thiolase_acyl_enz_int_AS.
DR   InterPro; IPR020610; Thiolase_AS.
DR   InterPro; IPR020617; Thiolase_C.
DR   InterPro; IPR020613; Thiolase_CS.
DR   InterPro; IPR020616; Thiolase_N.
DR   Pfam; PF02803; Thiolase_C; 1.
DR   Pfam; PF00108; Thiolase_N; 1.
DR   PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR   SUPFAM; SSF53901; SSF53901; 2.
DR   TIGRFAMs; TIGR01930; AcCoA-C-Actrans; 1.
DR   PROSITE; PS00098; THIOLASE_1; 1.
DR   PROSITE; PS00737; THIOLASE_2; 1.
DR   PROSITE; PS00099; THIOLASE_3; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q5LXA8.
DR   SWISS-2DPAGE; Q5LXA8.
KW   Acyltransferase {ECO:0000256|RuleBase:RU003557,
KW   ECO:0000313|EMBL:AAV93644.1};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001023};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001023};
KW   Transferase {ECO:0000256|RuleBase:RU003557,
KW   ECO:0000313|EMBL:AAV93644.1}.
FT   DOMAIN        4    260       Thiolase_N. {ECO:0000259|Pfam:PF00108}.
FT   DOMAIN      269    390       Thiolase_C. {ECO:0000259|Pfam:PF02803}.
FT   ACT_SITE     88     88       Acyl-thioester intermediate.
FT                                {ECO:0000256|PIRSR:PIRSR000429-1}.
FT   ACT_SITE    347    347       Proton acceptor. {ECO:0000256|PIRSR:
FT                                PIRSR000429-1}.
FT   ACT_SITE    377    377       Proton acceptor. {ECO:0000256|PIRSR:
FT                                PIRSR000429-1}.
SQ   SEQUENCE   391 AA;  40780 MW;  6B9D74B8174C8FC9 CRC64;
     MTNVVIASAA RTGVGSFGGS FANTPAHDLG AAVLEAVVER AGIDKAEVSE TILGQVLTAA
     QGQNPARQAH VNAGLPKESS AWGINQVCGS GLRAVALGAQ HILLGDAEIV AAGGQENMTL
     SPHAAALRAG HKMGDMKYID TMIRDGLWDA FNGYHMGQTA ENVAEQWQIS REMQDEFAVA
     SQNKAEAAQN AGKFADEIVP FIIKTRKGDI VMDKDEYIRH GATIEAMQKL RPAFTKDGSV
     TAANASGLND GAAATLLMTA ENAEKRGIEP LARIASYATA GLDPSIMGVG PIHASRKALA
     KAGWKVEDLD LVEANEAFAA QACAVNKDMG WDPAIVNVNG GAIAIGHPIG ASGCRVLNTL
     LFEMKRRNAK KGLATLCIGG GMGVALCVER D
//

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