(data stored in ACNUC22795 zone)

SWISSPROT: S1A7B_HUMAN

ID   S1A7B_HUMAN             Reviewed;         101 AA.
AC   Q5SY68;
DT   09-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   30-AUG-2017, entry version 103.
DE   RecName: Full=Protein S100-A7-like 2;
DE   AltName: Full=S100 calcium-binding protein A7-like 2;
GN   Name=S100A7L2; Synonyms=S100A7B;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16710414; DOI=10.1038/nature04727;
RA   Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D.,
RA   Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A.,
RA   Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F.,
RA   McDonald L., Evans R., Phillips K., Atkinson A., Cooper R., Jones C.,
RA   Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P.,
RA   Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I.S., Aubin K.,
RA   Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G.,
RA   Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D.,
RA   Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G.,
RA   Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J.,
RA   Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H.,
RA   Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L.,
RA   Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J.,
RA   Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R.,
RA   Hammond S., Harrison E.S.I., Hart E., Haugen E., Heath P.D.,
RA   Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G.,
RA   Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M.,
RA   Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J.,
RA   Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M.,
RA   Loveland J., Lovell J., Lush M.J., Lyne R., Martin S.,
RA   Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W., McLaren S.,
RA   Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N.,
RA   Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V.,
RA   Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J.,
RA   Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E.,
RA   Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C.,
RA   Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z.,
RA   Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E.,
RA   Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A.,
RA   Vaudin M., Sulston J.E., Durbin R.M., Hubbard T., Wooster R.,
RA   Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V.,
RA   Beck S., Rogers J., Bentley D.R.;
RT   "The DNA sequence and biological annotation of human chromosome 1.";
RL   Nature 441:315-321(2006).
RN   [2]
RP   IDENTIFICATION.
RX   PubMed=12664160; DOI=10.1007/s00239-002-2410-5;
RA   Kulski J.K., Lim C.P., Dunn D.S., Bellgard M.;
RT   "Genomic and phylogenetic analysis of the S100A7 (psoriasin) gene
RT   duplications within the region of the S100 gene cluster on human
RT   chromosome 1q21.";
RL   J. Mol. Evol. 56:397-406(2003).
CC   -!- INTERACTION:
CC       P31151:S100A7; NbExp=4; IntAct=EBI-12006206, EBI-357520;
CC   -!- SIMILARITY: Belongs to the S-100 family. {ECO:0000305}.
DR   EMBL; AL591704; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BR000043; FAA00016.1; -; Genomic_DNA.
DR   UniGene; Hs.647713; -.
DR   ProteinModelPortal; Q5SY68; -.
DR   SMR; Q5SY68; -.
DR   IntAct; Q5SY68; 3.
DR   STRING; 9606.ENSP00000405610; -.
DR   DMDM; 74744045; -.
DR   EPD; Q5SY68; -.
DR   PaxDb; Q5SY68; -.
DR   PeptideAtlas; Q5SY68; -.
DR   PRIDE; Q5SY68; -.
DR   Ensembl; ENST00000368724; ENSP00000357713; ENSG00000197364.
DR   Ensembl; ENST00000368725; ENSP00000357714; ENSG00000197364.
DR   UCSC; uc010pdx.3; human.
DR   GeneCards; S100A7L2; -.
DR   HGNC; HGNC:21655; S100A7L2.
DR   HPA; HPA057828; -.
DR   neXtProt; NX_Q5SY68; -.
DR   eggNOG; ENOG410JEQ8; Eukaryota.
DR   eggNOG; ENOG41114XT; LUCA.
DR   HOGENOM; HOG000154231; -.
DR   HOVERGEN; HBG095357; -.
DR   InParanoid; Q5SY68; -.
DR   OrthoDB; EOG091G0Y5T; -.
DR   PhylomeDB; Q5SY68; -.
DR   ChiTaRS; S100A7L2; human.
DR   PRO; PR:Q5SY68; -.
DR   Proteomes; UP000005640; Chromosome 1.
DR   Bgee; ENSG00000197364; -.
DR   CleanEx; HS_S100A7L2; -.
DR   GO; GO:0005615; C:extracellular space; IDA:UniProtKB.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0046914; F:transition metal ion binding; IEA:InterPro.
DR   CDD; cd00213; S-100; 1.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR   InterPro; IPR002048; EF_hand_dom.
DR   InterPro; IPR034325; S-100_dom.
DR   InterPro; IPR013787; S100_Ca-bd_sub.
DR   Pfam; PF01023; S_100; 1.
DR   SUPFAM; SSF47473; SSF47473; 1.
DR   PROSITE; PS00018; EF_HAND_1; 1.
DR   PROSITE; PS50222; EF_HAND_2; 1.
PE   1: Evidence at protein level;
DR   PRODOM; Q5SY68.
DR   SWISS-2DPAGE; Q5SY68.
KW   Calcium; Complete proteome; Metal-binding; Reference proteome; Repeat;
KW   Zinc.
FT   CHAIN         1    101       Protein S100-A7-like 2.
FT                                /FTId=PRO_0000270831.
FT   DOMAIN       13     48       EF-hand 1. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00448}.
FT   DOMAIN       50     85       EF-hand 2. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00448}.
FT   CA_BIND      63     74       2; high affinity. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00448}.
FT   METAL        87     87       Zinc. {ECO:0000250}.
FT   METAL        91     91       Zinc. {ECO:0000250}.
SQ   SEQUENCE   101 AA;  11302 MW;  D49E9BEB7CFBC97C CRC64;
     MNIPLGEKVM LDIVAMFRQY SGDDGRMDMP GLVNLMKENF PNFLSGCEKS DMDYLSNALE
     KKDDNKDKKV NYSEFLSLLG DITIDHHKIM HGVAPCSGGS Q
//

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