(data stored in ACNUC1829 zone)

SWISSPROT: Q5TQJ1_ANOGA

ID   Q5TQJ1_ANOGA            Unreviewed;       234 AA.
AC   Q5TQJ1;
DT   07-DEC-2004, integrated into UniProtKB/TrEMBL.
DT   23-OCT-2007, sequence version 3.
DT   30-AUG-2017, entry version 87.
DE   RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};
GN   ORFNames=AgaP_AGAP008527 {ECO:0000313|EMBL:EAA12176.4};
OS   Anopheles gambiae (African malaria mosquito).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicoidea;
OC   Culicidae; Anophelinae; Anopheles.
OX   NCBI_TaxID=7165 {ECO:0000313|Proteomes:UP000007062};
RN   [1] {ECO:0000313|EMBL:EAA12176.4, ECO:0000313|Proteomes:UP000007062}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PEST {ECO:0000313|EMBL:EAA12176.4,
RC   ECO:0000313|Proteomes:UP000007062};
RX   PubMed=12364791; DOI=10.1126/science.1076181;
RA   Holt R.A., Subramanian G.M., Halpern A., Sutton G.G., Charlab R.,
RA   Nusskern D.R., Wincker P., Clark A.G., Ribeiro J.M., Wides R.,
RA   Salzberg S.L., Loftus B., Yandell M., Majoros W.H., Rusch D.B.,
RA   Lai Z., Kraft C.L., Abril J.F., Anthouard V., Arensburger P.,
RA   Atkinson P.W., Baden H., de Berardinis V., Baldwin D., Benes V.,
RA   Biedler J., Blass C., Bolanos R., Boscus D., Barnstead M., Cai S.,
RA   Center A., Chaturverdi K., Christophides G.K., Chrystal M.A.,
RA   Clamp M., Cravchik A., Curwen V., Dana A., Delcher A., Dew I.,
RA   Evans C.A., Flanigan M., Grundschober-Freimoser A., Friedli L., Gu Z.,
RA   Guan P., Guigo R., Hillenmeyer M.E., Hladun S.L., Hogan J.R.,
RA   Hong Y.S., Hoover J., Jaillon O., Ke Z., Kodira C., Kokoza E.,
RA   Koutsos A., Letunic I., Levitsky A., Liang Y., Lin J.J., Lobo N.F.,
RA   Lopez J.R., Malek J.A., McIntosh T.C., Meister S., Miller J.,
RA   Mobarry C., Mongin E., Murphy S.D., O'Brochta D.A., Pfannkoch C.,
RA   Qi R., Regier M.A., Remington K., Shao H., Sharakhova M.V.,
RA   Sitter C.D., Shetty J., Smith T.J., Strong R., Sun J., Thomasova D.,
RA   Ton L.Q., Topalis P., Tu Z., Unger M.F., Walenz B., Wang A., Wang J.,
RA   Wang M., Wang X., Woodford K.J., Wortman J.R., Wu M., Yao A.,
RA   Zdobnov E.M., Zhang H., Zhao Q., Zhao S., Zhu S.C., Zhimulev I.,
RA   Coluzzi M., della Torre A., Roth C.W., Louis C., Kalush F.,
RA   Mural R.J., Myers E.W., Adams M.D., Smith H.O., Broder S.,
RA   Gardner M.J., Fraser C.M., Birney E., Bork P., Brey P.T., Venter J.C.,
RA   Weissenbach J., Kafatos F.C., Collins F.H., Hoffman S.L.;
RT   "The genome sequence of the malaria mosquito Anopheles gambiae.";
RL   Science 298:129-149(2002).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU361218};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU361218}.
CC   -!- SIMILARITY: Belongs to the tetraspanin (TM4SF) family.
CC       {ECO:0000256|RuleBase:RU361218, ECO:0000256|SAAS:SAAS00545671}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:EAA12176.4}.
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DR   EMBL; AAAB01008964; EAA12176.4; -; Genomic_DNA.
DR   RefSeq; XP_316915.4; XM_316915.4.
DR   STRING; 7165.AGAP008527-PA; -.
DR   PaxDb; Q5TQJ1; -.
DR   EnsemblMetazoa; AGAP008527-RA; AGAP008527-PA; AGAP008527.
DR   GeneID; 1277446; -.
DR   KEGG; aga:AgaP_AGAP008527; -.
DR   eggNOG; KOG3882; Eukaryota.
DR   eggNOG; ENOG4111IRY; LUCA.
DR   HOGENOM; HOG000230651; -.
DR   InParanoid; Q5TQJ1; -.
DR   KO; K06497; -.
DR   OMA; QTELDCC; -.
DR   OrthoDB; EOG091G12WV; -.
DR   PhylomeDB; Q5TQJ1; -.
DR   Proteomes; UP000007062; Chromosome 3R.
DR   GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; IBA:GO_Central.
DR   Gene3D; 1.10.1450.10; -; 1.
DR   InterPro; IPR000301; Tetraspanin.
DR   InterPro; IPR018499; Tetraspanin/Peripherin.
DR   InterPro; IPR018503; Tetraspanin_CS.
DR   InterPro; IPR008952; Tetraspanin_EC2.
DR   Pfam; PF00335; Tetraspannin; 1.
DR   PIRSF; PIRSF002419; Tetraspanin; 1.
DR   PRINTS; PR00259; TMFOUR.
DR   SUPFAM; SSF48652; SSF48652; 1.
DR   PROSITE; PS00421; TM4_1; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q5TQJ1.
DR   SWISS-2DPAGE; Q5TQJ1.
KW   Complete proteome {ECO:0000313|Proteomes:UP000007062};
KW   Membrane {ECO:0000256|RuleBase:RU361218,
KW   ECO:0000256|SAAS:SAAS00027997};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007062};
KW   Transmembrane {ECO:0000256|RuleBase:RU361218,
KW   ECO:0000256|SAAS:SAAS00429797};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU361218,
KW   ECO:0000256|SAAS:SAAS00028005}.
FT   TRANSMEM     12     34       Helical. {ECO:0000256|RuleBase:RU361218}.
FT   TRANSMEM     54     75       Helical. {ECO:0000256|RuleBase:RU361218}.
FT   TRANSMEM     82    105       Helical. {ECO:0000256|RuleBase:RU361218}.
FT   TRANSMEM    200    227       Helical. {ECO:0000256|RuleBase:RU361218}.
SQ   SEQUENCE   234 AA;  25616 MW;  D092121F53462AAD CRC64;
     MPSLGISCVR YMVFFFNFLF AITGLVVIVT GAIIQSNYYH YSNFVGDNFW TAPIVLIVIG
     SIIFVVACFG CCGAAKESPC MIITFSIFLA LVFLAEIGIG IAGYYKHEEL SGILEKGFNK
     TLDSYATDKG AQEAWNLVQS EMVCCGIKGP EDWEPIYKND TVPRACCHRM PVGVNKCTRE
     YASTEGCFSK LSSYLGSKSL ILAGIGIGLA IVQLIAVLLA CCLYGSFRRQ YETV
//

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