(data stored in ACNUC1104 zone)

SWISSPROT: Q65E04_BACLD

ID   Q65E04_BACLD            Unreviewed;       477 AA.
AC   Q65E04; Q62PH5;
DT   25-OCT-2004, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2004, sequence version 1.
DT   08-MAY-2019, entry version 111.
DE   SubName: Full=Putative Drug resistance transporter EmrB/QacA subfamily {ECO:0000313|EMBL:AAU25336.1};
GN   OrderedLocusNames=BL04026 {ECO:0000313|EMBL:AAU25336.1};
OS   Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / NBRC
OS   12200 / NCIMB 9375 / NRRL NRS-1264 / Gibson 46).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=279010 {ECO:0000313|EMBL:AAU25336.1, ECO:0000313|Proteomes:UP000000606};
RN   [1] {ECO:0000313|EMBL:AAU25336.1, ECO:0000313|Proteomes:UP000000606}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 14580 / DSM 13 / JCM 2505 / NBRC 12200 / NCIMB 9375 / NRRL
RC   NRS-1264 / Gibson 46 {ECO:0000313|Proteomes:UP000000606};
RX   PubMed=15461803; DOI=10.1186/gb-2004-5-10-r77;
RA   Rey M.W., Ramaiya P., Nelson B.A., Brody-Karpin S.D., Zaretsky E.J.,
RA   Tang M., Lopez de Leon A., Xiang H., Gusti V., Clausen I.G.,
RA   Olsen P.B., Rasmussen M.D., Andersen J.T., Jorgensen P.L.,
RA   Larsen T.S., Sorokin A., Bolotin A., Lapidus A., Galleron N.,
RA   Ehrlich S.D., Berka R.M.;
RT   "Complete genome sequence of the industrial bacterium Bacillus
RT   licheniformis and comparisons with closely related Bacillus species.";
RL   Genome Biol. 5:R77.1-R77.12(2004).
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC       {ECO:0000256|SAAS:SAAS00769108}.
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DR   EMBL; CP000002; AAU25336.1; -; Genomic_DNA.
DR   RefSeq; WP_011198382.1; NC_006322.1.
DR   STRING; 279010.BL04026; -.
DR   EnsemblBacteria; AAU25336; AAU25336; BL04026.
DR   GeneID; 3027771; -.
DR   KEGG; bli:BL04026; -.
DR   PATRIC; fig|279010.13.peg.3965; -.
DR   eggNOG; ENOG4105C0R; Bacteria.
DR   eggNOG; ENOG410XNN3; LUCA.
DR   HOGENOM; HOG000239124; -.
DR   OMA; WAINSYT; -.
DR   OrthoDB; 1108236at2; -.
DR   BioCyc; BLIC279010:BLI_RS19145-MONOMER; -.
DR   Proteomes; UP000000606; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   CDD; cd06174; MFS; 1.
DR   InterPro; IPR004638; EmrB-like.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   InterPro; IPR001411; Tet-R_TetB/Drug-R_transptr.
DR   PANTHER; PTHR23501; PTHR23501; 1.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   TIGRFAMs; TIGR00711; efflux_EmrB; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q65E04.
DR   SWISS-2DPAGE; Q65E04.
KW   Cell membrane {ECO:0000256|SAAS:SAAS00769078};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000606};
KW   Membrane {ECO:0000256|SAAS:SAAS00769060, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000606};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00769091,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00769070,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|SAAS:SAAS00769034}.
FT   TRANSMEM     12     34       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     46     66       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     78    101       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    107    128       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    140    158       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    164    185       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    197    217       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    229    246       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    267    289       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    301    319       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    331    351       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    357    381       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    402    419       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    431    451       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       12    457       MFS. {ECO:0000259|PROSITE:PS50850}.
SQ   SEQUENCE   477 AA;  50265 MW;  BC9E60646FA67BCA CRC64;
     MNRRPFNQRT VVSIVYVTAM FMAAMDASVI NMALPAIMTE FQTLPSAAGT VNIGYLVSLA
     VCLPAAGWLG DRFGTKRVFL AALSIFTAAS ALCGIADNLA ALNAFRVIQG AGGGLITPVG
     MAILFRTFPP HERAKISRVL VLPIAVAPAV GPIISGFLTD QLSWRWIFYI NIPIGMIILL
     FGLLYLHEHL EPEAGRFDWL GFLLAAPGMA LAVFALSQGP ARGFGSPDVL AAGAGGMMLL
     AILVFVELKA EHPLIELRLL KDRVFGMMSV ISLLTAGGLL GMLYIFPLLC QEALGYSATD
     TALITFPEAL GLMLASQLMP RSLAKLGPRR VISVALLGAA VLFGLLSLTG YGSNLWLLRL
     LLFLAGFFLG HAVGAAQVVC FANISSSSMG RATTLFNVQN RLGSAFGVAV MSCVLAVLSQ
     PSAGIEPDLS AYRTALLCAA GFLMAALFIA LKLKDADTGR QMDKHASAPK GAAASGE
//

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