(data stored in ACNUC27125 zone)

SWISSPROT: Q6CY80_KLULA

ID   Q6CY80_KLULA            Unreviewed;       373 AA.
AC   Q6CY80;
DT   16-AUG-2004, integrated into UniProtKB/TrEMBL.
DT   16-AUG-2004, sequence version 1.
DT   11-DEC-2019, entry version 86.
DE   SubName: Full=KLLA0A02475p {ECO:0000313|EMBL:CAH02697.1};
GN   ORFNames=KLLA0_A02475g {ECO:0000313|EMBL:CAH02697.1};
OS   Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 /
OS   NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX   NCBI_TaxID=284590 {ECO:0000313|Proteomes:UP000000598};
RN   [1] {ECO:0000313|EMBL:CAH02697.1, ECO:0000313|Proteomes:UP000000598}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 /
RC   WM37 {ECO:0000313|Proteomes:UP000000598};
RX   PubMed=15229592; DOI=10.1038/nature02579;
RG   Genolevures;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.F., Straub M.L.,
RA   Suleau A., Swennene D., Tekaia F., Wesolowski-Louvel M., Westhof E.,
RA   Wirth B., Zeniou-Meyer M., Zivanovic I., Bolotin-Fukuhara M., Thierry A.,
RA   Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J.,
RA   Wincker P., Souciet J.L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000256|PIRSR:PIRSR000189-1};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CR382121; CAH02697.1; -; Genomic_DNA.
DR   RefSeq; XP_451109.1; XM_451109.1.
DR   STRING; 28985.XP_451109.1; -.
DR   EnsemblFungi; CAH02697; CAH02697; KLLA0_A02475g.
DR   GeneID; 2896688; -.
DR   KEGG; kla:KLLA0_A02475g; -.
DR   eggNOG; KOG3923; Eukaryota.
DR   eggNOG; COG0665; LUCA.
DR   HOGENOM; HOG000046303; -.
DR   InParanoid; Q6CY80; -.
DR   OMA; VEDPKCY; -.
DR   Proteomes; UP000000598; Chromosome A.
DR   GO; GO:0003884; F:D-amino-acid oxidase activity; IEA:EnsemblFungi.
DR   GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR   GO; GO:0046436; P:D-alanine metabolic process; IEA:EnsemblFungi.
DR   GO; GO:1902114; P:D-valine metabolic process; IEA:EnsemblFungi.
DR   InterPro; IPR006181; D-amino_acid_oxidase_CS.
DR   InterPro; IPR023209; DAO.
DR   InterPro; IPR006076; FAD-dep_OxRdtase.
DR   PANTHER; PTHR11530; PTHR11530; 1.
DR   Pfam; PF01266; DAO; 1.
DR   PIRSF; PIRSF000189; D-aa_oxidase; 1.
DR   PROSITE; PS00677; DAO; 1.
PE   4: Predicted;
DR   PRODOM; Q6CY80.
DR   SWISS-2DPAGE; Q6CY80.
KW   FAD {ECO:0000256|PIRSR:PIRSR000189-1};
KW   Flavoprotein {ECO:0000256|PIRSR:PIRSR000189-1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000598}.
FT   DOMAIN          9..357
FT                   /note="DAO"
FT                   /evidence="ECO:0000259|Pfam:PF01266"
FT   NP_BIND         53..54
FT                   /note="FAD"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000189-1"
FT   BINDING         211
FT                   /note="FAD"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000189-1"
FT   BINDING         255
FT                   /note="Substrate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000189-1"
FT   BINDING         317
FT                   /note="Substrate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000189-1"
FT   BINDING         347
FT                   /note="Substrate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000189-1"
SQ   SEQUENCE   373 AA;  41509 MW;  641F962C8B56B33A CRC64;
     MSNKSQPLIT VVGAGISGLY VTYCLTELYG VPGENICIVA DYLPGDQSPT GYTSPWAGGV
     WSCISPDDKN VMWYDRFTYE NLPTLSEKLL DFYKGKDAEW LGLARRPSTE LWDYQPPKAK
     INSLSQYLEE YKVLSKEELA KFKPEGAQFG IAFNSWNFNC PVFIVNLANF LKQKHNVRFL
     KQKLTHIAQA KSFANKASKT DNGTHVVFNC TGLGSKKLSG VADHNLYPTR GQVAVISAPH
     IAESCLRYGK DYVTYIIPRP GKVHELVLGG FLQVDNWNAQ DTSKEETDDI LKRTTTLLPK
     IGNPENLPIL KIAAGLRPSR YGGPRVEKEI KEESEHLVVV HNYGASGYGY QSGLGMAFKA
     VSLAFDKQRP SKL
//

If you have problems or comments...

PBIL Back to PBIL home page