(data stored in ACNUC15260 zone)

SWISSPROT: Q6MFW7_RAT

ID   Q6MFW7_RAT              Unreviewed;       309 AA.
AC   Q6MFW7;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2004, sequence version 1.
DT   08-MAY-2019, entry version 126.
DE   RecName: Full=Olfactory receptor {ECO:0000256|RuleBase:RU363047};
GN   Name=Olr1739 {ECO:0000313|Ensembl:ENSRNOP00000075604,
GN   ECO:0000313|RGD:1333738};
GN   Synonyms=9430032L10Rik {ECO:0000313|RGD:1333738}, Gabbr1
GN   {ECO:0000313|RGD:1333738}, Mog {ECO:0000313|RGD:1333738},
GN   Olr1735_predicted {ECO:0000313|RGD:1333738}, Olr1736_predicted
GN   {ECO:0000313|RGD:1333738}, Olr1737_predicted
GN   {ECO:0000313|RGD:1333738}, Olr1738_predicted
GN   {ECO:0000313|RGD:1333738}, Olr1739_predicted
GN   {ECO:0000313|RGD:1333738}, Olr1742_predicted
GN   {ECO:0000313|RGD:1333738}, Olr1743_predicted
GN   {ECO:0000313|RGD:1333738}, Olr1744_predicted
GN   {ECO:0000313|RGD:1333738}, Olr1745_predicted
GN   {ECO:0000313|RGD:1333738}, Olr1746_predicted
GN   {ECO:0000313|RGD:1333738}, Olr1748_predicted
GN   {ECO:0000313|RGD:1333738}, Olr1749_predicted
GN   {ECO:0000313|RGD:1333738}, Olr1750_predicted
GN   {ECO:0000313|RGD:1333738}, Or11 {ECO:0000313|EMBL:CAE84080.1},
GN   Rps15-ps {ECO:0000313|RGD:1333738}, RT1-M3 {ECO:0000313|RGD:1333738},
GN   RT1-M3-2 {ECO:0000313|RGD:1333738}, RT1-M6-1
GN   {ECO:0000313|RGD:1333738}, Ubd {ECO:0000313|RGD:1333738}, Zfp57
GN   {ECO:0000313|RGD:1333738}, Znrd1 {ECO:0000313|RGD:1333738};
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
OC   Muroidea; Muridae; Murinae; Rattus.
OX   NCBI_TaxID=10116 {ECO:0000313|EMBL:CAE84080.1};
RN   [1] {ECO:0000313|EMBL:CAE84080.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Brown Norway {ECO:0000313|EMBL:CAE84080.1};
RA   Boehm S., Borzym K., Gelling S., Gimmel V., Heitmann K., Kosiura A.,
RA   Lang N., Lehrack S., Thiel J., Sontag M., Hurt P., Himmelbauer H.,
RA   Sudbrak R., Reinhardt R.;
RL   Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:CAE84080.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Brown Norway {ECO:0000313|EMBL:CAE84080.1};
RX   PubMed=15060004; DOI=10.1101/gr.1987704;
RA   Hurt P., Walter L., Sudbrak R., Klages S., Mueller I., Shiina T.,
RA   Inoko H., Lehrach H., Guenther E., Reinhardt R., Himmelbauer H.;
RT   "The genomic sequence and comparative analysis of the rat major
RT   histocompatibility complex.";
RL   Genome Res. 14:631-639(2004).
RN   [3] {ECO:0000313|Ensembl:ENSRNOP00000075604, ECO:0000313|Proteomes:UP000002494}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Brown Norway {ECO:0000313|Ensembl:ENSRNOP00000075604,
RC   ECO:0000313|Proteomes:UP000002494};
RX   PubMed=15057822; DOI=10.1038/nature02426;
RG   Rat Genome Sequencing Project Consortium;
RA   Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J.,
RA   Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G.,
RA   Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G.,
RA   Morgan M., Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G.,
RA   Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S.,
RA   Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T.,
RA   Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T.,
RA   Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A.,
RA   Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M.,
RA   Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K.,
RA   Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S.,
RA   Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J.,
RA   Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y.,
RA   Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A.,
RA   Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J.,
RA   D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R.,
RA   Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A.,
RA   Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E.,
RA   Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E.,
RA   Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J.,
RA   Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D.,
RA   Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M.,
RA   Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O.,
RA   Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O.,
RA   Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H.,
RA   Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S.,
RA   Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J.,
RA   Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M.,
RA   Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E.,
RA   Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F.,
RA   Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K.,
RA   Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S.,
RA   Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M.,
RA   Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M.,
RA   Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A.,
RA   Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S.,
RA   Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G.,
RA   Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H.,
RA   Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R.,
RA   Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M.,
RA   Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H.,
RA   Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S.,
RA   Collins F.S.;
RT   "Genome sequence of the Brown Norway rat yields insights into
RT   mammalian evolution.";
RL   Nature 428:493-521(2004).
RN   [4] {ECO:0000313|Ensembl:ENSRNOP00000075604}
RP   IDENTIFICATION.
RC   STRAIN=Brown Norway {ECO:0000313|Ensembl:ENSRNOP00000075604};
RG   Ensembl;
RL   Submitted (JUN-2015) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell membrane
CC       {ECO:0000256|RuleBase:RU363047, ECO:0000256|SAAS:SAAS00857205};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU363047,
CC       ECO:0000256|SAAS:SAAS00857205}.
CC   -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC       {ECO:0000256|RuleBase:RU000688, ECO:0000256|SAAS:SAAS00857212}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; AC112568; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BX883052; CAE84080.1; -; Genomic_DNA.
DR   RefSeq; NP_001001423.1; NM_001001423.1.
DR   STRING; 10116.ENSRNOP00000043563; -.
DR   Ensembl; ENSRNOT00000084853; ENSRNOP00000075604; ENSRNOG00000052839.
DR   GeneID; 405202; -.
DR   KEGG; rno:405202; -.
DR   UCSC; RGD:1333738; rat.
DR   CTD; 405202; -.
DR   RGD; 1333738; Olr1739.
DR   eggNOG; ENOG410JB2U; Eukaryota.
DR   eggNOG; ENOG411179S; LUCA.
DR   GeneTree; ENSGT00870000136672; -.
DR   HOGENOM; HOG000041364; -.
DR   OMA; CYATICH; -.
DR   OrthoDB; 1024914at2759; -.
DR   TreeFam; TF337210; -.
DR   Proteomes; UP000002494; Chromosome 20.
DR   Bgee; ENSRNOG00000052839; Expressed in 4 organ(s), highest expression level in spleen.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
DR   GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IBA:GO_Central.
DR   InterPro; IPR000276; GPCR_Rhodpsn.
DR   InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR   InterPro; IPR000725; Olfact_rcpt.
DR   Pfam; PF13853; 7tm_4; 1.
DR   PRINTS; PR00237; GPCRRHODOPSN.
DR   PRINTS; PR00245; OLFACTORYR.
DR   PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR   PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q6MFW7.
DR   SWISS-2DPAGE; Q6MFW7.
KW   Cell membrane {ECO:0000256|RuleBase:RU363047,
KW   ECO:0000256|SAAS:SAAS00857207};
KW   Complete proteome {ECO:0000313|Proteomes:UP000002494};
KW   G-protein coupled receptor {ECO:0000256|RuleBase:RU000688,
KW   ECO:0000256|SAAS:SAAS00857203};
KW   Membrane {ECO:0000256|RuleBase:RU363047,
KW   ECO:0000256|SAAS:SAAS00857208};
KW   Olfaction {ECO:0000256|RuleBase:RU363047,
KW   ECO:0000256|SAAS:SAAS00857209};
KW   Receptor {ECO:0000256|RuleBase:RU000688,
KW   ECO:0000256|SAAS:SAAS00857193, ECO:0000313|EMBL:CAE84080.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002494};
KW   Sensory transduction {ECO:0000256|RuleBase:RU363047,
KW   ECO:0000256|SAAS:SAAS00857210};
KW   Transducer {ECO:0000256|RuleBase:RU000688,
KW   ECO:0000256|SAAS:SAAS00857213};
KW   Transmembrane {ECO:0000256|RuleBase:RU000688,
KW   ECO:0000256|SAAS:SAAS00857211};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU363047,
KW   ECO:0000256|SAAS:SAAS00857194}.
FT   TRANSMEM     21     45       Helical. {ECO:0000256|RuleBase:RU363047}.
FT   TRANSMEM     98    117       Helical. {ECO:0000256|RuleBase:RU363047}.
FT   TRANSMEM    138    159       Helical. {ECO:0000256|RuleBase:RU363047}.
FT   TRANSMEM    194    222       Helical. {ECO:0000256|RuleBase:RU363047}.
FT   TRANSMEM    234    257       Helical. {ECO:0000256|RuleBase:RU363047}.
FT   TRANSMEM    269    289       Helical. {ECO:0000256|RuleBase:RU363047}.
FT   DOMAIN       38    287       G_PROTEIN_RECEP_F1_2.
FT                                {ECO:0000259|PROSITE:PS50262}.
SQ   SEQUENCE   309 AA;  34198 MW;  D24E3DADF194A3F4 CRC64;
     MNCSQAPDFI LLGLSRDPEK WQLLFSIFLA LYLLGLSGNL LLLLAIGADV HLHTPMYFFL
     SQLSLVDLCS ITTTAPKMLE TLWTGDGSIS FSGCLTQFYF FAVFADMDNL LLAVMAIDRY
     AAICQPLLYP LLMTPCRCGV LVSGSWGVTN CLSLTHTLLL SQLYFQTNQE IPHFFCDLGP
     LLLLSCSDTH LNEILMIVLV VIFTIGALLC IVSSYGCIFY AVARIPSAQG KRKALSTCSS
     HLSVVLLFYS TVFAAYLKPR SSSHSSGEVV AAVMYTLVTP TLNPFIYSLR NRDVKSSLRR
     ILNMEKSHK
//

If you have problems or comments...

PBIL Back to PBIL home page