(data stored in ACNUC15260 zone)

SWISSPROT: Q6UAG5_MOUSE

ID   Q6UAG5_MOUSE            Unreviewed;       305 AA.
AC   Q6UAG5;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2004, sequence version 1.
DT   08-MAY-2019, entry version 121.
DE   RecName: Full=Olfactory receptor {ECO:0000256|RuleBase:RU363047};
GN   Name=Olfr99 {ECO:0000313|EMBL:AAQ77024.1,
GN   ECO:0000313|MGI:MGI:2177482};
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
OC   Muroidea; Muridae; Murinae; Mus; Mus.
OX   NCBI_TaxID=10090 {ECO:0000313|EMBL:AAQ77024.1};
RN   [1] {ECO:0000313|EMBL:AAQ77024.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=129/SvJ {ECO:0000313|EMBL:AAQ77024.1};
RX   PubMed=14506126; DOI=10.1093/hmg/ddg317;
RA   Amadou C., Younger R.M., Sims S., Matthews L.H., Rogers J.,
RA   Kumanovics A., Ziegler A., Beck S., Lindahl K.F.;
RT   "Co-duplication of olfactory receptor and MHC class I genes in the
RT   mouse major histocompatibility complex.";
RL   Hum. Mol. Genet. 12:3025-3040(2003).
RN   [2] {ECO:0000313|EMBL:AAI06778.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=PCR rescued clones {ECO:0000313|EMBL:AAI06778.1};
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RA   Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H.,
RA   Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M.,
RA   Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S.,
RA   Feolo M., Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F.,
RA   Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J.,
RA   Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N.,
RA   Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B.,
RA   Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B.,
RA   Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S.,
RA   Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R.,
RA   Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L.,
RA   Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E.,
RA   Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J.,
RA   Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S.,
RA   Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D.,
RA   Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G.,
RA   Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J.,
RA   Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L.,
RA   Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D.,
RA   Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A.,
RA   Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S.,
RA   Makowski K.A., Bosak S., Malek J.;
RT   "The status, quality, and expansion of the NIH full-length cDNA
RT   project: the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SUBCELLULAR LOCATION: Cell membrane
CC       {ECO:0000256|RuleBase:RU363047, ECO:0000256|SAAS:SAAS00857205};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU363047,
CC       ECO:0000256|SAAS:SAAS00857205}.
CC   -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC       {ECO:0000256|RuleBase:RU000688, ECO:0000256|SAAS:SAAS00857212}.
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DR   EMBL; BC106777; AAI06778.1; -; mRNA.
DR   EMBL; AY374998; AAQ77024.1; -; Genomic_DNA.
DR   MGI; MGI:2177482; Olfr99.
DR   HOGENOM; HOG000041364; -.
DR   GO; GO:0016021; C:integral component of membrane; ISA:MGI.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; ISA:MGI.
DR   GO; GO:0007186; P:G protein-coupled receptor signaling pathway; ISA:MGI.
DR   GO; GO:0007608; P:sensory perception of smell; ISA:MGI.
DR   InterPro; IPR000276; GPCR_Rhodpsn.
DR   InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR   InterPro; IPR000725; Olfact_rcpt.
DR   Pfam; PF13853; 7tm_4; 1.
DR   PRINTS; PR00237; GPCRRHODOPSN.
DR   PRINTS; PR00245; OLFACTORYR.
DR   PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR   PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE   2: Evidence at transcript level;
DR   PRODOM; Q6UAG5.
DR   SWISS-2DPAGE; Q6UAG5.
KW   Cell membrane {ECO:0000256|RuleBase:RU363047,
KW   ECO:0000256|SAAS:SAAS00857207};
KW   G-protein coupled receptor {ECO:0000256|RuleBase:RU000688,
KW   ECO:0000256|SAAS:SAAS00857203};
KW   Membrane {ECO:0000256|RuleBase:RU363047,
KW   ECO:0000256|SAAS:SAAS00857208};
KW   Olfaction {ECO:0000256|RuleBase:RU363047,
KW   ECO:0000256|SAAS:SAAS00857209};
KW   Receptor {ECO:0000256|RuleBase:RU000688,
KW   ECO:0000256|SAAS:SAAS00857193, ECO:0000313|EMBL:AAQ77024.1};
KW   Sensory transduction {ECO:0000256|RuleBase:RU363047,
KW   ECO:0000256|SAAS:SAAS00857210};
KW   Transducer {ECO:0000256|RuleBase:RU000688,
KW   ECO:0000256|SAAS:SAAS00857213};
KW   Transmembrane {ECO:0000256|RuleBase:RU000688,
KW   ECO:0000256|SAAS:SAAS00857211};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU363047,
KW   ECO:0000256|SAAS:SAAS00857194}.
FT   TRANSMEM     28     46       Helical. {ECO:0000256|RuleBase:RU363047}.
FT   TRANSMEM     58     78       Helical. {ECO:0000256|RuleBase:RU363047}.
FT   TRANSMEM     98    117       Helical. {ECO:0000256|RuleBase:RU363047}.
FT   TRANSMEM    138    159       Helical. {ECO:0000256|RuleBase:RU363047}.
FT   TRANSMEM    194    222       Helical. {ECO:0000256|RuleBase:RU363047}.
FT   TRANSMEM    234    257       Helical. {ECO:0000256|RuleBase:RU363047}.
FT   TRANSMEM    269    289       Helical. {ECO:0000256|RuleBase:RU363047}.
FT   DOMAIN       38    287       G_PROTEIN_RECEP_F1_2.
FT                                {ECO:0000259|PROSITE:PS50262}.
SQ   SEQUENCE   305 AA;  33615 MW;  2300EA98C20228C6 CRC64;
     MNCSQAPTLI LLGLSSDAEK WQPLFSIFLV LYLLGLLGNL LLLLAIGTDV HLHTPMYFFL
     SQLSFVDLCF ITTTAPKMLE ALWTGDGSIS FSGCLTQLYF FAVFADMDNL LLAVMAIDRY
     AAICHPLRYS ALMTPFRCGV LVSGSWGVTN CVSLTHTLLL SKLYFHTNQE IPHFFCEFGP
     LLLLSCSDTH LNKILVIILV GILGISAVLC IVSSYGCIFY AVAKVPSAQG KRKALSTCSS
     HLSVVLLFYS TVFATYLKPP SSSRSSEEVV AAVMYSLVTP TLNPFIYSLR NKDVKSSLRR
     ILNME
//

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