(data stored in SCRATCH zone)

SWISSPROT: Q750F9_ASHGO

ID   Q750F9_ASHGO            Unreviewed;       458 AA.
AC   Q750F9;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2004, sequence version 1.
DT   11-DEC-2019, entry version 93.
DE   RecName: Full=NEDD8-activating enzyme E1 regulatory subunit {ECO:0000256|PIRNR:PIRNR039099};
GN   ORFNames=AGOS_AGL005W {ECO:0000313|EMBL:AAS54485.1};
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811 {ECO:0000313|EMBL:AAS54485.1, ECO:0000313|Proteomes:UP000000591};
RN   [1] {ECO:0000313|EMBL:AAS54485.1, ECO:0000313|Proteomes:UP000000591}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056
RC   {ECO:0000313|Proteomes:UP000000591};
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Pohlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2] {ECO:0000313|Proteomes:UP000000591}
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056
RC   {ECO:0000313|Proteomes:UP000000591};
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
CC   -!- FUNCTION: Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme.
CC       {ECO:0000256|PIRNR:PIRNR039099}.
CC   -!- PATHWAY: Protein modification; protein neddylation.
CC       {ECO:0000256|PIRNR:PIRNR039099}.
CC   -!- SIMILARITY: Belongs to the ubiquitin-activating E1 family. ULA1
CC       subfamily. {ECO:0000256|PIRNR:PIRNR039099}.
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DR   EMBL; AE016820; AAS54485.1; -; Genomic_DNA.
DR   RefSeq; NP_986661.1; NM_211723.1.
DR   STRING; 33169.AAS54485; -.
DR   EnsemblFungi; AAS54485; AAS54485; AGOS_AGL005W.
DR   GeneID; 4622960; -.
DR   KEGG; ago:AGOS_AGL005W; -.
DR   InParanoid; Q750F9; -.
DR   KO; K04532; -.
DR   OMA; RCKNAAS; -.
DR   UniPathway; UPA00885; -.
DR   Proteomes; UP000000591; Chromosome VII.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0019781; F:NEDD8 activating enzyme activity; IBA:GO_Central.
DR   GO; GO:0032446; P:protein modification by small protein conjugation; IBA:GO_Central.
DR   GO; GO:0045116; P:protein neddylation; IBA:GO_Central.
DR   InterPro; IPR030667; APP-BP1.
DR   InterPro; IPR035985; Ubiquitin-activating_enz.
DR   PIRSF; PIRSF039099; APP-BP1; 1.
DR   SUPFAM; SSF69572; SSF69572; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q750F9.
DR   SWISS-2DPAGE; Q750F9.
KW   Reference proteome {ECO:0000313|Proteomes:UP000000591};
KW   Ubl conjugation pathway {ECO:0000256|PIRNR:PIRNR039099}.
SQ   SEQUENCE   458 AA;  50762 MW;  38B8ACC0E80A9B21 CRC64;
     MDRYDRQKRL WGASGQQGLR HAHVCVIGGA DGGLWCEVAK NLALSGVGAV RIISTGSSDD
     SYERFFQPAE LCSLNTDVGW SFSSWKGAAV AAEQWSECSA LIVTTGAPGV VEEVTAKWRE
     RKMPVLLSAH CASVYGYVRL LSPETHCVIE AHPQHRVPDL QLYAGWGELD ELCGKTAVSQ
     LDPEERQDVP FAVLLRSAVR SLGRKPASRE EARAALDDLY TPNHSGATIE DMNFLEAVKY
     AHLALAPTEP VLPRVAEAWA AMPPDLEQVG DPFNRQFWVL VRALKQYFTA YGSLPLSGEL
     PDMESSTVRY YELKDCYEQK ARADRKRLAG FLSSTIPDAV IDAFCRNLRY LRIIRPSKLI
     GLDESLSELK RVNTDGAMLL SALLSIQYGI QEPTVNKKGS EYLNNINRFS GSNFYPTVAF
     IGGVLAQEAT KFLTHQYVPI ENTFVYDGLL NTTETIML
//

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