(data stored in SCRATCH zone)

SWISSPROT: Q750U4_ASHGO

ID   Q750U4_ASHGO            Unreviewed;       198 AA.
AC   Q750U4;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2004, sequence version 1.
DT   11-DEC-2019, entry version 86.
DE   RecName: Full=Transcription initiation factor TFIID subunit 10 {ECO:0000256|PIRNR:PIRNR017246};
GN   ORFNames=AGOS_AGL155W {ECO:0000313|EMBL:AAS54336.1};
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811 {ECO:0000313|EMBL:AAS54336.1, ECO:0000313|Proteomes:UP000000591};
RN   [1] {ECO:0000313|EMBL:AAS54336.1, ECO:0000313|Proteomes:UP000000591}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056
RC   {ECO:0000313|Proteomes:UP000000591};
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Pohlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2] {ECO:0000313|Proteomes:UP000000591}
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056
RC   {ECO:0000313|Proteomes:UP000000591};
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
CC   -!- FUNCTION: Functions as a component of the DNA-binding general
CC       transcription factor complex TFIID and the transcription regulatory
CC       histone acetylation (HAT) complexes SAGA and SLIK. Binding of TFIID to
CC       a promoter (with or without TATA element) is the initial step in
CC       preinitiation complex (PIC) formation. TFIID plays a key role in the
CC       regulation of gene expression by RNA polymerase II through different
CC       activities such as transcription activator interaction, core promoter
CC       recognition and selectivity, TFIIA and TFIIB interaction, chromatin
CC       modification (histone acetylation), facilitation of DNA opening and
CC       initiation of transcription. SAGA is required for recruitment of the
CC       basal transcription machinery. SLIK is proposed to have partly
CC       overlapping functions with SAGA. {ECO:0000256|PIRNR:PIRNR017246}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PIRNR:PIRNR017246}.
CC   -!- SIMILARITY: Belongs to the TAF10 family.
CC       {ECO:0000256|PIRNR:PIRNR017246}.
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DR   EMBL; AE016820; AAS54336.1; -; Genomic_DNA.
DR   RefSeq; NP_986512.1; NM_211574.1.
DR   STRING; 33169.AAS54336; -.
DR   EnsemblFungi; AAS54336; AAS54336; AGOS_AGL155W.
DR   GeneID; 4622805; -.
DR   KEGG; ago:AGOS_AGL155W; -.
DR   HOGENOM; HOG000175811; -.
DR   InParanoid; Q750U4; -.
DR   KO; K03134; -.
DR   OMA; NPPIIPD; -.
DR   Proteomes; UP000000591; Chromosome VII.
DR   GO; GO:0000124; C:SAGA complex; IEA:EnsemblFungi.
DR   GO; GO:0046695; C:SLIK (SAGA-like) complex; IEA:EnsemblFungi.
DR   GO; GO:0005669; C:transcription factor TFIID complex; IEA:EnsemblFungi.
DR   GO; GO:0003682; F:chromatin binding; IEA:EnsemblFungi.
DR   GO; GO:0042802; F:identical protein binding; IEA:EnsemblFungi.
DR   GO; GO:0060090; F:molecular adaptor activity; IEA:EnsemblFungi.
DR   GO; GO:0016573; P:histone acetylation; IEA:EnsemblFungi.
DR   GO; GO:0051123; P:RNA polymerase II preinitiation complex assembly; IEA:EnsemblFungi.
DR   CDD; cd07982; TAF10; 1.
DR   InterPro; IPR003923; TFIID_30kDa.
DR   PANTHER; PTHR21242; PTHR21242; 1.
DR   Pfam; PF03540; TFIID_30kDa; 1.
DR   PIRSF; PIRSF017246; TFIID_TAF10; 1.
DR   PRINTS; PR01443; TFIID30KDSUB.
PE   3: Inferred from homology;
DR   PRODOM; Q750U4.
DR   SWISS-2DPAGE; Q750U4.
KW   Nucleus {ECO:0000256|PIRNR:PIRNR017246};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000591};
KW   Transcription {ECO:0000256|PIRNR:PIRNR017246};
KW   Transcription regulation {ECO:0000256|PIRNR:PIRNR017246}.
FT   REGION          21..47
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          150..171
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   198 AA;  22348 MW;  D6D798380E6552F6 CRC64;
     MSEKEVTIDE DLNVDDELNE FDDGEEAPVD NAMLFGSQPP EDRAGADPKH RKLFEIPEFT
     RKDKTVNELL DLMTDNPPII PDAVIDYYLT KNGFECTDVR VKRLLALATQ KFVSDIAADA
     YEYSRIRSSI AVHNSNNGQA RARQLMLGQQ QPGTQQISQQ QHQQNEKTNA NKVTLTVNDL
     SSAVAEYGLN ISRPDFYR
//

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