(data stored in ACNUC22857 zone)

SWISSPROT: Q753X2_ASHGO

ID   Q753X2_ASHGO            Unreviewed;       694 AA.
AC   Q753X2;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2010, sequence version 2.
DT   05-JUL-2017, entry version 93.
DE   RecName: Full=AP complex subunit beta {ECO:0000256|PIRNR:PIRNR002291};
GN   ORFNames=AGOS_AFR200W {ECO:0000313|EMBL:AAS53571.2};
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL
OS   Y-1056) (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
OC   Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811 {ECO:0000313|EMBL:AAS53571.2, ECO:0000313|Proteomes:UP000000591};
RN   [1] {ECO:0000313|EMBL:AAS53571.2, ECO:0000313|Proteomes:UP000000591}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056
RC   {ECO:0000313|Proteomes:UP000000591};
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Pohlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient
RT   Saccharomyces cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2] {ECO:0000313|Proteomes:UP000000591}
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056
RC   {ECO:0000313|Proteomes:UP000000591};
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
CC   -!- FUNCTION: Adaptins are components of the adaptor complexes which
CC       link clathrin to receptors in coated vesicles. Clathrin-associated
CC       protein complexes are believed to interact with the cytoplasmic
CC       tails of membrane proteins, leading to their selection and
CC       concentration. {ECO:0000256|PIRNR:PIRNR002291}.
CC   -!- SIMILARITY: Belongs to the adaptor complexes large subunit family.
CC       {ECO:0000256|PIRNR:PIRNR002291}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; AE016819; AAS53571.2; -; Genomic_DNA.
DR   RefSeq; NP_985747.2; NM_211101.2.
DR   ProteinModelPortal; Q753X2; -.
DR   STRING; 33169.AAS53571; -.
DR   EnsemblFungi; AAS53571; AAS53571; AGOS_AFR200W.
DR   GeneID; 4622008; -.
DR   KEGG; ago:AGOS_AFR200W; -.
DR   HOGENOM; HOG000163270; -.
DR   InParanoid; Q753X2; -.
DR   OMA; ARASMVW; -.
DR   OrthoDB; EOG092C18N0; -.
DR   Proteomes; UP000000591; Chromosome VI.
DR   GO; GO:0030121; C:AP-1 adaptor complex; IEA:EnsemblFungi.
DR   GO; GO:0030276; F:clathrin binding; IEA:EnsemblFungi.
DR   GO; GO:0008565; F:protein transporter activity; IEA:InterPro.
DR   GO; GO:0006896; P:Golgi to vacuole transport; IEA:EnsemblFungi.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   Gene3D; 1.25.10.10; -; 1.
DR   InterPro; IPR026739; AP_beta.
DR   InterPro; IPR016342; AP_complex_bsu_1_2_4.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR002553; Clathrin/coatomer_adapt-like_N.
DR   PANTHER; PTHR11134; PTHR11134; 1.
DR   Pfam; PF01602; Adaptin_N; 1.
DR   PIRSF; PIRSF002291; AP_complex_beta; 1.
DR   SUPFAM; SSF48371; SSF48371; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q753X2.
DR   SWISS-2DPAGE; Q753X2.
KW   Complete proteome {ECO:0000313|Proteomes:UP000000591};
KW   Membrane {ECO:0000256|PIRNR:PIRNR002291,
KW   ECO:0000256|SAAS:SAAS00101884};
KW   Protein transport {ECO:0000256|PIRNR:PIRNR002291,
KW   ECO:0000256|SAAS:SAAS00468902};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000591};
KW   Transport {ECO:0000256|PIRNR:PIRNR002291,
KW   ECO:0000256|SAAS:SAAS00299740}.
FT   DOMAIN       22    550       Adaptin_N. {ECO:0000259|Pfam:PF01602}.
SQ   SEQUENCE   694 AA;  78326 MW;  52C04BD335DAE7D1 CRC64;
     MDKKIKRFLK DAVRVAPKIS NKGELFELKN GLVSKYPQTR KDAIKKTIQQ MTLGKDVSSL
     FPDVLKNIAT SDIEQKKLVY LYVINYAQTH PELCILAVNT FVTDAQDPNP LIRCMAIRTM
     SMIRVDKILE HVEIPLRKTL QDDNPYVRKT AVICVAKLFQ LNRELCMELD VLTDLMSALD
     DSNPMVVANS IAALTEIYEL DRSAVPLPLL IQSHVTQFLN ALNECTEWAR ITILGALAQY
     EAKDAMEAQD TIVRVTPHLQ HVNAAVVLAS VKVIVKNLDF LPREMQKQPS EKISTALVSL
     MSTPPEMQYV ALKTIRILLQ KYPTLLEKEL RIFYVKFNDP MYVKLEKLDI MVRLVTTSNL
     KQCSTLLLEL REYALEFEPE FVSKAILAIS QLAIKFAHGA DAVNASKFIA KAIDILSTLI
     QDRNTFQDEC LISICDLLRY DPQLSGMPLS IISSWTDAES RLVTDQGKCN YIWLLGQYQF
     PNAEEKLMQF VDTYPQQGQS TQMSILVTVV KLSQQLPGHV LQRVLELATT QAQDIDIRDM
     AMLYWRCLSL PNPESLINEL CNTKLPQLTN TLDYFSPELL HTLLNELSTL SSIYYKPLSQ
     FKYRAPQQSE VQSKALDELT SLAHAEIAKN MNNETLLNMD DAQAAPKPGN TLAELSDLFG
     NTGGSLLDKP MQDMSLHADS RTVQGASKDL LDLF
//

If you have problems or comments...

PBIL Back to PBIL home page