(data stored in SCRATCH zone)

SWISSPROT: Q757I7_ASHGO

ID   Q757I7_ASHGO            Unreviewed;       334 AA.
AC   Q757I7;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2004, sequence version 1.
DT   11-DEC-2019, entry version 78.
DE   RecName: Full=25S rRNA adenine-N(1) methyltransferase {ECO:0000256|HAMAP-Rule:MF_03044};
DE            EC=2.1.1.- {ECO:0000256|HAMAP-Rule:MF_03044};
GN   Name=BMT2 {ECO:0000256|HAMAP-Rule:MF_03044};
GN   ORFNames=AGOS_AER026C {ECO:0000313|EMBL:AAS52710.1};
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811 {ECO:0000313|EMBL:AAS52710.1, ECO:0000313|Proteomes:UP000000591};
RN   [1] {ECO:0000313|EMBL:AAS52710.1, ECO:0000313|Proteomes:UP000000591}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056
RC   {ECO:0000313|Proteomes:UP000000591};
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Pohlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2] {ECO:0000313|Proteomes:UP000000591}
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056
RC   {ECO:0000313|Proteomes:UP000000591};
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
CC   -!- FUNCTION: S-adenosyl-L-methionine-dependent methyltransferase that
CC       specifically methylates the N(1) position of an adenine present in
CC       helix 65 in 25S rRNA. {ECO:0000256|HAMAP-Rule:MF_03044}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000256|HAMAP-
CC       Rule:MF_03044}.
CC   -!- SIMILARITY: Belongs to the BMT2 family. {ECO:0000256|HAMAP-
CC       Rule:MF_03044}.
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DR   EMBL; AE016818; AAS52710.1; -; Genomic_DNA.
DR   RefSeq; NP_984886.1; NM_210240.1.
DR   STRING; 33169.AAS52710; -.
DR   EnsemblFungi; AAS52710; AAS52710; AGOS_AER026C.
DR   GeneID; 4621088; -.
DR   KEGG; ago:AGOS_AER026C; -.
DR   HOGENOM; HOG000171862; -.
DR   InParanoid; Q757I7; -.
DR   KO; K18849; -.
DR   OMA; IIRRFHL; -.
DR   Proteomes; UP000000591; Chromosome V.
DR   GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR   GO; GO:0016433; F:rRNA (adenine) methyltransferase activity; IBA:GO_Central.
DR   HAMAP; MF_03044; BMT2; 1.
DR   InterPro; IPR021867; Bmt2/SAMTOR.
DR   InterPro; IPR029063; SAM-dependent_MTases.
DR   PANTHER; PTHR21008; PTHR21008; 1.
DR   Pfam; PF11968; Bmt2; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q757I7.
DR   SWISS-2DPAGE; Q757I7.
KW   Methyltransferase {ECO:0000256|HAMAP-Rule:MF_03044};
KW   Nucleus {ECO:0000256|HAMAP-Rule:MF_03044};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000591};
KW   S-adenosyl-L-methionine {ECO:0000256|HAMAP-Rule:MF_03044};
KW   Transferase {ECO:0000256|HAMAP-Rule:MF_03044}.
FT   REGION          1..20
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         164
FT                   /note="S-adenosyl-L-methionine"
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_03044"
FT   BINDING         185
FT                   /note="S-adenosyl-L-methionine"
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_03044"
SQ   SEQUENCE   334 AA;  37468 MW;  C86C99566F71B2D1 CRC64;
     MLARKRRSIT GKSAVKHTPA IKPSKARKVI RRYHVLLQKR RAICKLLGIP VAENDEVLNE
     RQIARYVTDA GLQEQYRLGA DMAHPDEKVE RELLKIQKMR ESPLLVQMLG YVMAEINGPR
     GLQNYQAAST VGQTASRGGD TSRQLVPWLR EAGTPADARA LEIGALSAAN CISTCGLLRT
     VVRIDLHSND STAIEEQDFM LRPLPQADAD AFDLISCSLV LNFVPTPLAR GEMLLRFRSF
     LRGPRPLLFI VLPLPCMENS RYMNSEYFCN MMTALGYNCL YQRSAKKLIY FLFASRTGMP
     APYPLKYTRK HQLADGPAMN NFSITLPALS SPRI
//

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