(data stored in SCRATCH zone)

SWISSPROT: Q757I8_ASHGO

ID   Q757I8_ASHGO            Unreviewed;      2911 AA.
AC   Q757I8;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2010, sequence version 2.
DT   11-DEC-2019, entry version 92.
DE   SubName: Full=AER025Cp {ECO:0000313|EMBL:AAS52709.2};
GN   ORFNames=AGOS_AER025C {ECO:0000313|EMBL:AAS52709.2};
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811 {ECO:0000313|EMBL:AAS52709.2, ECO:0000313|Proteomes:UP000000591};
RN   [1] {ECO:0000313|EMBL:AAS52709.2, ECO:0000313|Proteomes:UP000000591}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056
RC   {ECO:0000313|Proteomes:UP000000591};
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Pohlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2] {ECO:0000313|Proteomes:UP000000591}
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056
RC   {ECO:0000313|Proteomes:UP000000591};
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
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DR   EMBL; AE016818; AAS52709.2; -; Genomic_DNA.
DR   RefSeq; NP_984885.2; NM_210239.2.
DR   STRING; 33169.AAS52709; -.
DR   EnsemblFungi; AAS52709; AAS52709; AGOS_AER025C.
DR   GeneID; 4621087; -.
DR   KEGG; ago:AGOS_AER025C; -.
DR   HOGENOM; HOG000113101; -.
DR   InParanoid; Q757I8; -.
DR   OMA; RLYNIVF; -.
DR   Proteomes; UP000000591; Chromosome V.
DR   GO; GO:0043087; P:regulation of GTPase activity; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 3.40.525.10; -; 1.
DR   InterPro; IPR036865; CRAL-TRIO_dom_sf.
DR   InterPro; IPR039360; Ras_GTPase.
DR   InterPro; IPR023152; RasGAP_CS.
DR   InterPro; IPR001936; RasGAP_dom.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   PANTHER; PTHR10194; PTHR10194; 2.
DR   Pfam; PF00616; RasGAP; 1.
DR   SMART; SM00323; RasGAP; 1.
DR   SUPFAM; SSF48350; SSF48350; 1.
DR   PROSITE; PS00509; RAS_GTPASE_ACTIV_1; 1.
DR   PROSITE; PS50018; RAS_GTPASE_ACTIV_2; 1.
PE   4: Predicted;
DR   PRODOM; Q757I8.
DR   SWISS-2DPAGE; Q757I8.
KW   Reference proteome {ECO:0000313|Proteomes:UP000000591}.
FT   DOMAIN          1537..1726
FT                   /note="Ras-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50018"
FT   REGION          372..404
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          417..444
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   2911 AA;  331585 MW;  30AAB340BA415475 CRC64;
     MVKNLICRIF NRLEQLLPTE LNDFVYSEVE RHPIFSNARL ALLNAGVTQG LQLVVDPLLE
     VVERIAEKNR PESGSTSGIS SAVATLSVME SYTEDVLHSL LVMLRLLNDI IEVTWQSYES
     NHAGDEAEPG REAGTVNGFY STYKVGFATE KEWTHAMAPP ALETTAAQQL LRISNRFKTR
     SQTLEILKKI ANSLHRPETL NSRLKVPDTL HNERSQTRSE LLDKIDDNCE ALMKHVAASN
     PHEYHSYINT RIISPLLVTQ TQNETDIATY LDAFSFYFIT NKYLVSFLEL VSKMVTYFKK
     SVYQEVLLKF VSQAMTTWIL SRPQEYLDVI DRIKYHPEDQ STQLLIKEAS FLFEEIYNSF
     SVTHILTESP TLQSTMSSPT SAGGSTSSIP GDGTSPAKGS NAAHSISSAT IVITNSVDDP
     MRPSTVPDTG EHASNHPRMT GNPDNVENIT HMSVLSFLSC MVMLHPGAFE EINNTSFRNI
     PDDPHLNESK EDITDSLYAT TSGTTSVNSD ERIRHSQHRR LKSFKKLTAF STHSSNHHKV
     KFLSALVDNL TGIHAVSDAA IVDSLRTLIL ISSLAASVFQ FEKDAPSIHF SRRLFPVLCD
     SLQLCSEQNA RRNPLIAKCL FRHYTLHSSL QIDYFPVACS LEPDAFNLRL QEYLEQRNNS
     LGHLHILTEG LKAYVCVQRN MPSEFKTLLA TIGLLRRTAY GLSCVLIEGS PLFDDRSSVS
     AVIDDLLEGR LIDELNIDDS DDGDPRIPAF MNAFVPKESM KSFPQTPSVP SFTSSSFNEK
     TPSAPFIFPN KSDHDAVRIR RPSIGSPQPT LHGRLTTTSS LPHDLERVQY SMRASMDRGV
     RPPLRMSSRG RYGSQDSIMH LMRSTSFVGN EALQEVRKDA SNLYIVRKII GNIYAIYKAV
     LHFSMSVLEA EKISPLHIDD YKDVVKPVFA ALIDDGADSH SAVKAYCYVG ITCIDELAGE
     HANKYMPSVF KANGYLIALL AASLFNVSLT DSKREQIFGY LTDFWEFRQA IVKYFEKRGI
     LSKISDEELY TFPVIRGATG RALCVSMYSH NPNIHRLLKI GFRLFQKEIA NHHLVNGHRV
     TTGQFNLQFI KAMGRDSYLS TGALAFQRRL RSDILARIKH PDRILYDSLR LIYNHWYSLL
     TAEHRSDTES NHFRNCAGFI AASCGVFLAA DDDILEKFSY LYQVRDSMVE KIDYFIYKQC
     QSINNEDLLT RENSRDIVSS ELHPLAFALL FKHLKKKAKD LFDIKITQPE NELHYVLLEQ
     IILVIRVILE RDDDTDVLIC VSLDLIELLG DIFKIIELMP RDSPKYYKII IQISKMLRSF
     EHSEQKICIS GCMLIKNKWL RLTMRWFEST IFREYDLENL GKPHRSMDLQ RRDLDYLYID
     TSIESSKALA YLTKDLVLEA PQSMSEKELS RSKEVVFGNY FTILLKGLEK STGIKKFPPT
     LRHKIGMLND NIITSLTNLL NYNVDVGFKY ALPIGYSPNR NIKLAFLKVF VNIVSNFDVT
     KKRLEEERSA AIETLLDRAV EDPKLLSKAA RVCPANDIDS LAGSFVTLYD IKNAAHLIVI
     ELIIDEISRA TRYMDVLRRN SCATRSLSMF SRLKGGAYLI NVLKPVLEEV VATGETFDVE
     KIEPDDPDCQ IHVDLFCKYL NKLVDSIVGS VADFPPEFFV ICQSIYSSVK ENFPDSAEIA
     VGSFIFLRFF CPALVSPDSE GITDPLYPKA RRSFMILAKV IQNIANGSVS SLKWPALQSE
     VEFLKTISDR IFCYLKEISD PTRKVEIRTK PENRASVDDF HMLHRFLYYH GFEIRREFIN
     DVKSAEDMGR LREFCRLADR LLSLLGQPRM EFKSAISPYI RDHMDTNPEL YEFMSRHSLK
     NILPEDTPFV REGVSPDGFP IIVLTWHLCD RILKRESDAL VFRIFQIYSK VWTTSHYCVI
     DCTGFDCQKY EEPVRKLSNL FYKLIPHDAA KNCTGFYYYN MTENLLDLWL PIFRDKARYL
     SGLKIPHHFI NSNSPTKAIS MLGLSDYSLE VYTDVRVTLH DASVYNSKDK KFYPVTLKIG
     NKHFQVIHDT PKSINLGIME TALDIYFNDV YDIAEIKSTG LSNEVGVPYE FTIIMDDGNK
     LIFTSTKCLE ILKIFYYSQV RLEEEFRDDE FGVSSMAHDH NKRKDMTYTI GHILMIVFVG
     LTSEDDAAES VAYNLMAATQ STFDLDCGHK LTVPPEVYVS GDNSAFYNSI LNTLAVTTPE
     LCECIWTYAL DLLENVLNKK QITALLIALS PWTKNLYEYV YLANDEEGPE ITTQIIRRLI
     RITMKQELHS ILYAQLIFSN ILLEGDLTEL LFDEVIHHCV DRASEGSEWK RIIVILTKVP
     TTEVCGLVLR KIQKISNSFL PTLQLETSTH SWSELIILVE VAVSLFFDSL LLAQLHLSEI
     LCIVSLLIDV GPTELRSALH RLLMNVCHSF VNNERLYEPQ KENLKKISIT LSRQKLKFMF
     GFSQDKGRVL QNFSPSSFLT KFTTLEHFIS NLLELMGNAS VNHSTVLCWK TKYLKYIMDV
     VTNVESFLSS RAMMIIGIIS KNGINDNLCY KLLRQTFRTL SVPWITEESI FYAISHIFAY
     SKIVNGLQPT SKLLPQMFWF STTYIRSPKS MVYQGGLLLM MNSAQRMSLA SGGENAPPLL
     SQLYKERQFV EAVMDEQGRV DGMRFTEANF IHILMAYLSK GLLIPFVRTT AVEALITFFR
     LTFHKSPYQA DDNYLVFMFF IYLVQRPDHF NEMLNEMDPD SEIISLDDTT GIDSRLLSWM
     ENGSDTALFA LYQGAVYFSS RNSDEPGKVR FLLLLKHLVV KQPFMVFKVY NVIRDELGRI
     NTYDVSNTNT VTVAFFVIRL MVVQKDYLKL DDIQQEMQNH LATRGLSGIS DIDIDAAKKE
     SELSPEKQIE SILPRKVHAL QIVDQMLSLS G
//

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