(data stored in SCRATCH zone)

SWISSPROT: Q757M1_ASHGO

ID   Q757M1_ASHGO            Unreviewed;       339 AA.
AC   Q757M1;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2010, sequence version 2.
DT   11-DEC-2019, entry version 112.
DE   SubName: Full=AEL010Wp {ECO:0000313|EMBL:AAS52675.2};
GN   ORFNames=AGOS_AEL010W {ECO:0000313|EMBL:AAS52675.2};
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811 {ECO:0000313|EMBL:AAS52675.2, ECO:0000313|Proteomes:UP000000591};
RN   [1] {ECO:0000313|EMBL:AAS52675.2, ECO:0000313|Proteomes:UP000000591}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056
RC   {ECO:0000313|Proteomes:UP000000591};
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Pohlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2] {ECO:0000313|Proteomes:UP000000591}
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056
RC   {ECO:0000313|Proteomes:UP000000591};
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|SAAS:SAAS00882743};
CC   -!- SIMILARITY: Belongs to the PP2C family.
CC       {ECO:0000256|RuleBase:RU003465}.
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DR   EMBL; AE016818; AAS52675.2; -; Genomic_DNA.
DR   RefSeq; NP_984851.2; NM_210205.2.
DR   STRING; 33169.AAS52675; -.
DR   EnsemblFungi; AAS52675; AAS52675; AGOS_AEL010W.
DR   GeneID; 4621050; -.
DR   KEGG; ago:AGOS_AEL010W; -.
DR   HOGENOM; HOG000233896; -.
DR   InParanoid; Q757M1; -.
DR   KO; K19704; -.
DR   OMA; VCDEAIR; -.
DR   Proteomes; UP000000591; Chromosome V.
DR   GO; GO:0005737; C:cytoplasm; IEA:EnsemblFungi.
DR   GO; GO:0005634; C:nucleus; IEA:EnsemblFungi.
DR   GO; GO:0004724; F:magnesium-dependent protein serine/threonine phosphatase activity; IBA:GO_Central.
DR   GO; GO:1990439; F:MAP kinase serine/threonine phosphatase activity; IBA:GO_Central.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004722; F:protein serine/threonine phosphatase activity; IBA:GO_Central.
DR   GO; GO:0051389; P:inactivation of MAPKK activity; IEA:EnsemblFungi.
DR   GO; GO:0000001; P:mitochondrion inheritance; IEA:EnsemblFungi.
DR   GO; GO:0035970; P:peptidyl-threonine dephosphorylation; IEA:EnsemblFungi.
DR   GO; GO:0000750; P:pheromone-dependent signal transduction involved in conjugation with cellular fusion; IEA:EnsemblFungi.
DR   GO; GO:0006388; P:tRNA splicing, via endonucleolytic cleavage and ligation; IEA:EnsemblFungi.
DR   CDD; cd00143; PP2Cc; 1.
DR   Gene3D; 3.60.40.10; -; 1.
DR   InterPro; IPR015655; PP2C.
DR   InterPro; IPR000222; PP2C_BS.
DR   InterPro; IPR036457; PPM-type_dom_sf.
DR   InterPro; IPR001932; PPM-type_phosphatase_dom.
DR   PANTHER; PTHR13832; PTHR13832; 1.
DR   Pfam; PF00481; PP2C; 1.
DR   SMART; SM00331; PP2C_SIG; 1.
DR   SMART; SM00332; PP2Cc; 1.
DR   SUPFAM; SSF81606; SSF81606; 1.
DR   PROSITE; PS01032; PPM_1; 1.
DR   PROSITE; PS51746; PPM_2; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q757M1.
DR   SWISS-2DPAGE; Q757M1.
KW   Hydrolase {ECO:0000256|RuleBase:RU003465, ECO:0000256|SAAS:SAAS00927111};
KW   Magnesium {ECO:0000256|SAAS:SAAS00882703};
KW   Metal-binding {ECO:0000256|SAAS:SAAS00882779};
KW   Protein phosphatase {ECO:0000256|RuleBase:RU003465,
KW   ECO:0000256|SAAS:SAAS00927143};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000591}.
FT   DOMAIN          74..335
FT                   /note="PPM-type phosphatase"
FT                   /evidence="ECO:0000259|PROSITE:PS51746"
FT   REGION          1..67
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   339 AA;  37527 MW;  D5829C25391B0515 CRC64;
     MGYNETEPAI DGDNNEQRIN EDMSTLEHTS NNNGNGLEPV EAGPDSGIPA VEGGGSVSGQ
     SPQHEPPAYE LSYVVGVAEN KNAKFRRTME DVHTYVENFA SRLDWGYFAI FDGHAGNQAS
     KWCGSHLHTI IEERILQGDD RDVRDILNDS FVYVDQQINS TLEGNSGCTA AVGILRWEAP
     TPIPNMPINL EQHKRMLYTA NVGDTRIILF RNGRSVRLTY DHKASDIIEM QRVEKAGGLI
     MKSRVNGMLA VTRSLGDKFF DSLVVGNPFT TSVEITTSDQ FLIIACDGLW DVVDDQEACE
     MIKDIEDANE AAKTLVRHAL EHGTTDNVTV MVVFFDNNQ
//

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