(data stored in SCRATCH zone)

SWISSPROT: Q757W0_ASHGO

ID   Q757W0_ASHGO            Unreviewed;       487 AA.
AC   Q757W0;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2010, sequence version 2.
DT   11-DEC-2019, entry version 96.
DE   SubName: Full=AEL098Wp {ECO:0000313|EMBL:AAS52587.2};
GN   ORFNames=AGOS_AEL098W {ECO:0000313|EMBL:AAS52587.2};
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811 {ECO:0000313|EMBL:AAS52587.2, ECO:0000313|Proteomes:UP000000591};
RN   [1] {ECO:0000313|EMBL:AAS52587.2, ECO:0000313|Proteomes:UP000000591}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056
RC   {ECO:0000313|Proteomes:UP000000591};
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Pohlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2] {ECO:0000313|Proteomes:UP000000591}
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056
RC   {ECO:0000313|Proteomes:UP000000591};
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
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DR   EMBL; AE016818; AAS52587.2; -; Genomic_DNA.
DR   RefSeq; NP_984763.2; NM_210117.2.
DR   STRING; 33169.AAS52587; -.
DR   ESTHER; ashgo-q757w0; Homoserine_transacetylase.
DR   EnsemblFungi; AAS52587; AAS52587; AGOS_AEL098W.
DR   GeneID; 4620953; -.
DR   KEGG; ago:AGOS_AEL098W; -.
DR   HOGENOM; HOG000246301; -.
DR   InParanoid; Q757W0; -.
DR   OMA; MRFAQRS; -.
DR   Proteomes; UP000000591; Chromosome V.
DR   GO; GO:0004414; F:homoserine O-acetyltransferase activity; IBA:GO_Central.
DR   GO; GO:0009092; P:homoserine metabolic process; IBA:GO_Central.
DR   GO; GO:0009086; P:methionine biosynthetic process; IBA:GO_Central.
DR   HAMAP; MF_00296; MetX_acyltransf; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR000073; AB_hydrolase_1.
DR   InterPro; IPR008220; HAT_MetX-like.
DR   PANTHER; PTHR32268; PTHR32268; 1.
DR   Pfam; PF00561; Abhydrolase_1; 1.
DR   PIRSF; PIRSF000443; Homoser_Ac_trans; 1.
DR   SUPFAM; SSF53474; SSF53474; 1.
DR   TIGRFAMs; TIGR01392; homoserO_Ac_trn; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q757W0.
DR   SWISS-2DPAGE; Q757W0.
KW   Reference proteome {ECO:0000313|Proteomes:UP000000591}.
FT   DOMAIN          110..453
FT                   /note="AB hydrolase-1"
FT                   /evidence="ECO:0000259|Pfam:PF00561"
FT   ACT_SITE        216
FT                   /note="Nucleophile"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000443-1"
FT   ACT_SITE        431
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000443-1"
FT   ACT_SITE        466
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000443-1"
SQ   SEQUENCE   487 AA;  53756 MW;  0E5F6C50D2DEDE59 CRC64;
     MTSFLYSGKR FIAKAAGRST NPQMSFPCLD KLDALTAKLK ENRIGSINGG STVGDFYGTL
     ADNEPVYGNV KSGYQLYSCE EPLLLDYGGV LLGFRIAYET WGTLNAERSN AVLLHTGLSA
     SSHARSSELN GIPGWWEKFI GPGSKILDTN RFFVVCTNVL GGCYGSTGPS SADPADGEPY
     ATRFPILSIQ DIVRAQHKLV RECFGIEKLY ASVGSSMGGM QSLAYGQLFP SDVEKIVSIS
     ACAQSDPSSI ALRHAQRQVL MADVNWNRGL YYPSEKYPDR IPPHVGMKLA REIATVTYRS
     GPEWESRFGT ERLDPDGTPT LCPDFLVESY LNHQGEKFSL EYDANSFLYL SKTMDLFDLS
     ASHLRRSQQK RMEAAVRLKR GTLSNTSSVY AEPPTKKKSR TISIEENHRD LVEGMAPLRD
     KDILIIGVQS DALFPAAQQR KIVELLGNSR GVHYIELTQE QSIFGHDTFL LDTEHIGLPI
     GKFLSGT
//

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