(data stored in SCRATCH zone)

SWISSPROT: Q758H2_ASHGO

ID   Q758H2_ASHGO            Unreviewed;       126 AA.
AC   Q758H2;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2004, sequence version 1.
DT   11-DEC-2019, entry version 76.
DE   RecName: Full=Mitochondrial pyruvate carrier {ECO:0000256|RuleBase:RU363100};
GN   ORFNames=AGOS_AEL210C {ECO:0000313|EMBL:AAS52475.1};
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811 {ECO:0000313|EMBL:AAS52475.1, ECO:0000313|Proteomes:UP000000591};
RN   [1] {ECO:0000313|EMBL:AAS52475.1, ECO:0000313|Proteomes:UP000000591}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056
RC   {ECO:0000313|Proteomes:UP000000591};
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Pohlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2] {ECO:0000313|Proteomes:UP000000591}
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056
RC   {ECO:0000313|Proteomes:UP000000591};
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
CC   -!- FUNCTION: Mediates the uptake of pyruvate into mitochondria.
CC       {ECO:0000256|RuleBase:RU363100}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC       {ECO:0000256|RuleBase:RU363100}; Multi-pass membrane protein
CC       {ECO:0000256|RuleBase:RU363100}.
CC   -!- SIMILARITY: Belongs to the mitochondrial pyruvate carrier (MPC)
CC       (TC 2.A.105) family. {ECO:0000256|RuleBase:RU363100}.
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DR   EMBL; AE016818; AAS52475.1; -; Genomic_DNA.
DR   RefSeq; NP_984651.1; NM_210004.1.
DR   STRING; 33169.AAS52475; -.
DR   EnsemblFungi; AAS52475; AAS52475; AGOS_AEL210C.
DR   GeneID; 4620833; -.
DR   KEGG; ago:AGOS_AEL210C; -.
DR   HOGENOM; HOG000188910; -.
DR   InParanoid; Q758H2; -.
DR   KO; K22139; -.
DR   OMA; GQLARIW; -.
DR   Proteomes; UP000000591; Chromosome V.
DR   GO; GO:0031305; C:integral component of mitochondrial inner membrane; IBA:GO_Central.
DR   GO; GO:0050833; F:pyruvate transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0006850; P:mitochondrial pyruvate transmembrane transport; IBA:GO_Central.
DR   InterPro; IPR005336; MPC.
DR   Pfam; PF03650; MPC; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q758H2.
DR   SWISS-2DPAGE; Q758H2.
KW   Membrane {ECO:0000256|RuleBase:RU363100};
KW   Mitochondrion {ECO:0000256|RuleBase:RU363100};
KW   Mitochondrion inner membrane {ECO:0000256|RuleBase:RU363100};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000591};
KW   Transport {ECO:0000256|RuleBase:RU363100}.
SQ   SEQUENCE   126 AA;  14045 MW;  081F58E6C4862D32 CRC64;
     MSTAAAGRAF RRFWQSETGP RTVHFWAPTL KWGLVVAGIS DMQRPVERVS GTQNLSLMAT
     AVIWTRWSFV IRPKNYLLAS VNFFLGLTAS YQLARIARYR LREGDSAGEV LRYIVNGPRD
     PAGAAA
//

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