(data stored in SCRATCH zone)

SWISSPROT: EAF6_ASHGO

ID   EAF6_ASHGO              Reviewed;          98 AA.
AC   Q75BT5; Q75BT6;
DT   20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   11-DEC-2019, entry version 82.
DE   RecName: Full=Chromatin modification-related protein EAF6;
GN   Name=EAF6; OrderedLocusNames=ACR185W;
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
CC   -!- FUNCTION: Component of the NuA4 histone acetyltransferase complex which
CC       is involved in transcriptional activation of selected genes principally
CC       by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is
CC       also involved in DNA repair (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Component of the NuA4 histone acetyltransferase complex.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the EAF6 family. {ECO:0000305}.
DR   EMBL; AE016816; AAS51411.2; -; Genomic_DNA.
DR   RefSeq; NP_983587.2; NM_208940.2.
DR   SMR; Q75BT5; -.
DR   STRING; 33169.AAS51411; -.
DR   EnsemblFungi; AAS51411; AAS51411; AGOS_ACR185W.
DR   GeneID; 4619719; -.
DR   KEGG; ago:AGOS_ACR185W; -.
DR   HOGENOM; HOG000066089; -.
DR   InParanoid; Q75BT5; -.
DR   KO; K11344; -.
DR   OMA; FVKQQEG; -.
DR   Proteomes; UP000000591; Chromosome III.
DR   GO; GO:0070776; C:MOZ/MORF histone acetyltransferase complex; IBA:GO_Central.
DR   GO; GO:1990467; C:NuA3a histone acetyltransferase complex; IBA:GO_Central.
DR   GO; GO:1990468; C:NuA3b histone acetyltransferase complex; IBA:GO_Central.
DR   GO; GO:0035267; C:NuA4 histone acetyltransferase complex; IBA:GO_Central.
DR   GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0043968; P:histone H2A acetylation; IBA:GO_Central.
DR   GO; GO:0044154; P:histone H3-K14 acetylation; IBA:GO_Central.
DR   GO; GO:0043972; P:histone H3-K23 acetylation; IEA:GOC.
DR   GO; GO:0043983; P:histone H4-K12 acetylation; IBA:GO_Central.
DR   GO; GO:0043981; P:histone H4-K5 acetylation; IBA:GO_Central.
DR   GO; GO:0043982; P:histone H4-K8 acetylation; IBA:GO_Central.
DR   InterPro; IPR015418; Eaf6.
DR   PANTHER; PTHR13476; PTHR13476; 1.
DR   Pfam; PF09340; NuA4; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q75BT5.
DR   SWISS-2DPAGE; Q75BT5.
KW   Chromatin regulator; Coiled coil; DNA damage; DNA repair; Nucleus;
KW   Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..98
FT                   /note="Chromatin modification-related protein EAF6"
FT                   /id="PRO_0000086893"
FT   COILED          1..36
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   98 AA;  11553 MW;  947010B64EBEC299 CRC64;
     MEKQRKEYEE LKQKLKQALH EKKVQEQEWD QIQQEIFDKE TEYLSGNASS KYGTIVKGFD
     GFGKHASQDS HHFQDQDRIF SLSSALFVKQ QEGVQDEE
//

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