(data stored in SCRATCH zone)

SWISSPROT: Q75CW6_ASHGO

ID   Q75CW6_ASHGO            Unreviewed;       463 AA.
AC   Q75CW6;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2004, sequence version 1.
DT   11-DEC-2019, entry version 90.
DE   RecName: Full=Mannan endo-1,6-alpha-mannosidase {ECO:0000256|PIRNR:PIRNR016302};
DE            EC=3.2.1.101 {ECO:0000256|PIRNR:PIRNR016302};
GN   ORFNames=AGOS_ACL200W {ECO:0000313|EMBL:AAS51028.1};
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811 {ECO:0000313|EMBL:AAS51028.1, ECO:0000313|Proteomes:UP000000591};
RN   [1] {ECO:0000313|EMBL:AAS51028.1, ECO:0000313|Proteomes:UP000000591}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056
RC   {ECO:0000313|Proteomes:UP000000591};
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Pohlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2] {ECO:0000313|Proteomes:UP000000591}
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056
RC   {ECO:0000313|Proteomes:UP000000591};
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Random hydrolysis of (1->6)-alpha-D-mannosidic linkages in
CC         unbranched (1->6)-mannans.; EC=3.2.1.101;
CC         Evidence={ECO:0000256|PIRNR:PIRNR016302};
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 76 family.
CC       {ECO:0000256|PIRNR:PIRNR016302}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE016816; AAS51028.1; -; Genomic_DNA.
DR   RefSeq; NP_983204.1; NM_208557.1.
DR   CAZy; GH76; Glycoside Hydrolase Family 76.
DR   EnsemblFungi; AAS51028; AAS51028; AGOS_ACL200W.
DR   GeneID; 4619324; -.
DR   KEGG; ago:AGOS_ACL200W; -.
DR   HOGENOM; HOG000178818; -.
DR   InParanoid; Q75CW6; -.
DR   OMA; YERACEP; -.
DR   Proteomes; UP000000591; Chromosome III.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008496; F:mannan endo-1,6-alpha-mannosidase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0007117; P:budding cell bud growth; IBA:GO_Central.
DR   GO; GO:0016052; P:carbohydrate catabolic process; IEA:InterPro.
DR   GO; GO:0009272; P:fungal-type cell wall biogenesis; IBA:GO_Central.
DR   InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR   InterPro; IPR005198; Glyco_hydro_76.
DR   InterPro; IPR014480; Mannan-1_6-alpha_mannosidase.
DR   PANTHER; PTHR12145; PTHR12145; 1.
DR   Pfam; PF03663; Glyco_hydro_76; 1.
DR   PIRSF; PIRSF016302; Man_a_manosd; 1.
DR   SUPFAM; SSF48208; SSF48208; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q75CW6.
DR   SWISS-2DPAGE; Q75CW6.
KW   Glycosidase {ECO:0000256|PIRNR:PIRNR016302};
KW   Hydrolase {ECO:0000256|PIRNR:PIRNR016302};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000591};
KW   Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..30
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           31..463
FT                   /note="Mannan endo-1,6-alpha-mannosidase"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5004286546"
FT   TRANSMEM        441..461
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   463 AA;  51513 MW;  E8ADD37CBB72F648 CRC64;
     MTVAFVRVGA EPSLPMYVLL VILNIVLSNA LDVDFNSSES ICDATKLIQV GILDYYEGLR
     PGGRVGFFQK PYYWWMAGEA FGGMVENWYL CNNTEYQDLL TDAMVSQIGE NKDYVPSHQK
     MIEGNDDQGI WGLLVMGAAE RNFPDAPPER APGWLALAQA VFNTMWARWD PENCGGGLRW
     QIFPWNNGYD YKNTISNACL FQIAARLARF TGNSTYQDVA ETVFDWLVDS KLVQLENDAK
     VLDGAHISER CEDHSKLEWT YNHGVVLAGC AYMYNITNGS AVWGDRLNKV LNGSLLFFPN
     GILYERACQD VQKCNDDQRS FRSIFSRMLA LTSVLAPHTK ARIEPNIRKS AEAAAKSCSG
     GRDGHTCGMV WRNYTWDGKY GLGEQLSALE IIQNTLIHTK PPPTTANEGA KSKGDPSAGL
     YDNSPNIITL STRQIGLKDR VGAGFMTVVL LIPFITGSIW MSI
//

If you have problems or comments...

PBIL Back to PBIL home page