(data stored in ACNUC31183 zone)

SWISSPROT: Q7QG72_ANOGA

ID   Q7QG72_ANOGA            Unreviewed;       869 AA.
AC   Q7QG72;
DT   15-DEC-2003, integrated into UniProtKB/TrEMBL.
DT   23-OCT-2007, sequence version 4.
DT   30-AUG-2017, entry version 79.
DE   SubName: Full=AGAP009533-PA {ECO:0000313|EMBL:EAA05897.4};
DE   Flags: Fragment;
GN   Name=1271375 {ECO:0000313|VectorBase:AGAP009533-PA};
GN   ORFNames=AgaP_AGAP009533 {ECO:0000313|EMBL:EAA05897.4};
OS   Anopheles gambiae (African malaria mosquito).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicoidea;
OC   Culicidae; Anophelinae; Anopheles.
OX   NCBI_TaxID=7165 {ECO:0000313|Proteomes:UP000007062};
RN   [1] {ECO:0000313|VectorBase:AGAP009533-PA}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PEST {ECO:0000313|VectorBase:AGAP009533-PA};
RX   PubMed=9087549; DOI=10.1111/j.1365-2583.1993.tb00131.x;
RA   Beard C.B., Hamm D.M., Collins F.H.;
RT   "The mitochondrial genome of the mosquito Anopheles gambiae: DNA
RT   sequence, genome organization, and comparisons with mitochondrial
RT   sequences of other insects.";
RL   Insect Mol. Biol. 2:103-124(1993).
RN   [2] {ECO:0000313|EMBL:EAA05897.4, ECO:0000313|Proteomes:UP000007062}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PEST {ECO:0000313|EMBL:EAA05897.4,
RC   ECO:0000313|Proteomes:UP000007062};
RX   PubMed=12364791; DOI=10.1126/science.1076181;
RA   Holt R.A., Subramanian G.M., Halpern A., Sutton G.G., Charlab R.,
RA   Nusskern D.R., Wincker P., Clark A.G., Ribeiro J.M., Wides R.,
RA   Salzberg S.L., Loftus B., Yandell M., Majoros W.H., Rusch D.B.,
RA   Lai Z., Kraft C.L., Abril J.F., Anthouard V., Arensburger P.,
RA   Atkinson P.W., Baden H., de Berardinis V., Baldwin D., Benes V.,
RA   Biedler J., Blass C., Bolanos R., Boscus D., Barnstead M., Cai S.,
RA   Center A., Chaturverdi K., Christophides G.K., Chrystal M.A.,
RA   Clamp M., Cravchik A., Curwen V., Dana A., Delcher A., Dew I.,
RA   Evans C.A., Flanigan M., Grundschober-Freimoser A., Friedli L., Gu Z.,
RA   Guan P., Guigo R., Hillenmeyer M.E., Hladun S.L., Hogan J.R.,
RA   Hong Y.S., Hoover J., Jaillon O., Ke Z., Kodira C., Kokoza E.,
RA   Koutsos A., Letunic I., Levitsky A., Liang Y., Lin J.J., Lobo N.F.,
RA   Lopez J.R., Malek J.A., McIntosh T.C., Meister S., Miller J.,
RA   Mobarry C., Mongin E., Murphy S.D., O'Brochta D.A., Pfannkoch C.,
RA   Qi R., Regier M.A., Remington K., Shao H., Sharakhova M.V.,
RA   Sitter C.D., Shetty J., Smith T.J., Strong R., Sun J., Thomasova D.,
RA   Ton L.Q., Topalis P., Tu Z., Unger M.F., Walenz B., Wang A., Wang J.,
RA   Wang M., Wang X., Woodford K.J., Wortman J.R., Wu M., Yao A.,
RA   Zdobnov E.M., Zhang H., Zhao Q., Zhao S., Zhu S.C., Zhimulev I.,
RA   Coluzzi M., della Torre A., Roth C.W., Louis C., Kalush F.,
RA   Mural R.J., Myers E.W., Adams M.D., Smith H.O., Broder S.,
RA   Gardner M.J., Fraser C.M., Birney E., Bork P., Brey P.T., Venter J.C.,
RA   Weissenbach J., Kafatos F.C., Collins F.H., Hoffman S.L.;
RT   "The genome sequence of the malaria mosquito Anopheles gambiae.";
RL   Science 298:129-149(2002).
RN   [3] {ECO:0000313|EMBL:EAA05897.4}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=PEST {ECO:0000313|EMBL:EAA05897.4};
RG   The Anopheles Genome Sequencing Consortium;
RL   Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN   [4] {ECO:0000313|EMBL:EAA05897.4}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=PEST {ECO:0000313|EMBL:EAA05897.4};
RX   PubMed=14747013; DOI=10.1016/j.pt.2003.11.003;
RA   Mongin E., Louis C., Holt R.A., Birney E., Collins F.H.;
RT   "The Anopheles gambiae genome: an update.";
RL   Trends Parasitol. 20:49-52(2004).
RN   [5] {ECO:0000313|EMBL:EAA05897.4}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=PEST {ECO:0000313|EMBL:EAA05897.4};
RX   PubMed=17210077; DOI=10.1186/gb-2007-8-1-r5;
RA   Sharakhova M.V., Hammond M.P., Lobo N.F., Krzywinski J., Unger M.F.,
RA   Hillenmeyer M.E., Bruggner R.V., Birney E., Collins F.H.;
RT   "Update of the Anopheles gambiae PEST genome assembly.";
RL   Genome Biol. 8:R5-R5(2007).
RN   [6] {ECO:0000313|EMBL:EAA05897.4}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=PEST {ECO:0000313|EMBL:EAA05897.4};
RG   VectorBase;
RL   Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN   [7] {ECO:0000313|VectorBase:AGAP009533-PA}
RP   IDENTIFICATION.
RC   STRAIN=PEST {ECO:0000313|VectorBase:AGAP009533-PA};
RG   VectorBase;
RL   Submitted (FEB-2017) to UniProtKB.
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DR   EMBL; AAAB01008839; EAA05897.4; -; Genomic_DNA.
DR   RefSeq; XP_310156.4; XM_310156.4.
DR   STRING; 7165.AGAP009533-PA; -.
DR   PaxDb; Q7QG72; -.
DR   EnsemblMetazoa; AGAP009533-RA; AGAP009533-PA; AGAP009533.
DR   GeneID; 1271375; -.
DR   KEGG; aga:AgaP_AGAP009533; -.
DR   VectorBase; AGAP009533-RA; AGAP009533-PA; AGAP009533.
DR   eggNOG; KOG3686; Eukaryota.
DR   eggNOG; ENOG410XTIX; LUCA.
DR   HOGENOM; HOG000231640; -.
DR   InParanoid; Q7QG72; -.
DR   KO; K17700; -.
DR   OMA; VANQEHM; -.
DR   OrthoDB; EOG091G028T; -.
DR   PhylomeDB; Q7QG72; -.
DR   Proteomes; UP000007062; Chromosome 3R.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
DR   InterPro; IPR000331; Rap_GAP_dom.
DR   Pfam; PF02145; Rap_GAP; 1.
DR   SUPFAM; SSF111347; SSF111347; 1.
DR   PROSITE; PS50085; RAPGAP; 1.
PE   4: Predicted;
DR   PRODOM; Q7QG72.
DR   SWISS-2DPAGE; Q7QG72.
KW   Complete proteome {ECO:0000313|Proteomes:UP000007062};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007062}.
FT   DOMAIN      261    477       Rap-GAP. {ECO:0000259|PROSITE:PS50085}.
FT   NON_TER       1      1       {ECO:0000313|EMBL:EAA05897.4}.
SQ   SEQUENCE   869 AA;  92475 MW;  019DAD2EB7B626A8 CRC64;
     NTRSAEERIA NPHSTNESTN NLSVQIPQSM GGGGNTRSLL RHSNSMSSNP HSNSNSTPAS
     PHLLSNSSSV HLHHAGAGGG GLHHHQQQHP QYQSQSSVSS QSSSIISTVP PVQRLLEDAL
     SKPGPHPMII VPNSGGYWVD GTDHDASYEV PSHTTWRVGK IESDDTAKCY RRFFIAREHS
     NLVGHDDQLG PVLLSIKSEN VANQEHIRIL LRLRTGTMHE LIPASCLGSS PSPIKMARLL
     NEQINVDSFM PVLCPKASAL IASYDEHVLV TNFKFGVLYQ RFGQTAEEEL FCNSETTPAF
     DEFLDVLGQR IRLRDHKGYR GGLDIQNGHT GDTAVYDVFK EREIMFHVST LLPYTEADPQ
     QLQRKRHIGN DIVAIVFQEE NTPFSPAMIA SHFLHAFIVV QPIEPNTPNC RYKISVTARD
     DVPFFGPTLP QPSVFKRGPE LKEFLLTKLI NAENACYKAD KFAQLELRTR SSLLQNLVDE
     LKEKTRDFLG MDVGGGAAGV PTSPTPETPK SEGGFTGSRF IDTVKKALNA RLRSQNSDPT
     NNGSGGAGSV DTATGGGGAK HHNSMKKSKD GTSLVSDMPC GPGGAVNIGR SLSKSSTTGS
     RKSPNDSVAS SPDITSRCSL NPTLTNNNNN NSNAPNNNNN NTIGKNHPNG SANGNGAGGN
     AAAGGGNNNN GPVAMSETSD DSSLNSVDLD PMVFLPTVDA GATYIDSDTG LESMSSADAT
     TKACSLCLDG TGSTNGGGSV VSVSISGASV TIDGGNAREL RNSGGSASSG TGSTASAGQM
     GCGSVVGQGA ASVTQETLQQ VEGMRQEITR LKCDKLDLLR QNVTCQRDIK RLRERELSLQ
     GDLAAAGKEI LRLRDLLKEC LPTAVADPI
//

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