(data stored in ACNUC27125 zone)

SWISSPROT: Q7S8L1_NEUCR

ID   Q7S8L1_NEUCR            Unreviewed;       412 AA.
AC   Q7S8L1;
DT   15-DEC-2003, integrated into UniProtKB/TrEMBL.
DT   15-DEC-2003, sequence version 1.
DT   11-DEC-2019, entry version 80.
DE   SubName: Full=TBC domain-containing protein {ECO:0000313|EMBL:EAA32673.1};
GN   ORFNames=NCU05272 {ECO:0000313|EMBL:EAA32673.1};
OS   Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 /
OS   FGSC 987).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
OX   NCBI_TaxID=367110 {ECO:0000313|EMBL:EAA32673.1, ECO:0000313|Proteomes:UP000001805};
RN   [1] {ECO:0000313|EMBL:EAA32673.1, ECO:0000313|Proteomes:UP000001805}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987
RC   {ECO:0000313|Proteomes:UP000001805};
RX   PubMed=12712197; DOI=10.1038/nature01554;
RA   Galagan J.E., Calvo S.E., Borkovich K.A., Selker E.U., Read N.D., Jaffe D.,
RA   FitzHugh W., Ma L.J., Smirnov S., Purcell S., Rehman B., Elkins T.,
RA   Engels R., Wang S., Nielsen C.B., Butler J., Endrizzi M., Qui D.,
RA   Ianakiev P., Bell-Pedersen D., Nelson M.A., Werner-Washburne M.,
RA   Selitrennikoff C.P., Kinsey J.A., Braun E.L., Zelter A., Schulte U.,
RA   Kothe G.O., Jedd G., Mewes W., Staben C., Marcotte E., Greenberg D.,
RA   Roy A., Foley K., Naylor J., Stange-Thomann N., Barrett R., Gnerre S.,
RA   Kamal M., Kamvysselis M., Mauceli E., Bielke C., Rudd S., Frishman D.,
RA   Krystofova S., Rasmussen C., Metzenberg R.L., Perkins D.D., Kroken S.,
RA   Cogoni C., Macino G., Catcheside D., Li W., Pratt R.J., Osmani S.A.,
RA   DeSouza C.P., Glass L., Orbach M.J., Berglund J.A., Voelker R., Yarden O.,
RA   Plamann M., Seiler S., Dunlap J., Radford A., Aramayo R., Natvig D.O.,
RA   Alex L.A., Mannhaupt G., Ebbole D.J., Freitag M., Paulsen I., Sachs M.S.,
RA   Lander E.S., Nusbaum C., Birren B.;
RT   "The genome sequence of the filamentous fungus Neurospora crassa.";
RL   Nature 422:859-868(2003).
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DR   EMBL; CM002239; EAA32673.1; -; Genomic_DNA.
DR   RefSeq; XP_961909.1; XM_956816.2.
DR   EnsemblFungi; EAA32673; EAA32673; NCU05272.
DR   GeneID; 3878062; -.
DR   KEGG; ncr:NCU05272; -.
DR   EuPathDB; FungiDB:NCU05272; -.
DR   HOGENOM; HOG000211712; -.
DR   InParanoid; Q7S8L1; -.
DR   KO; K20372; -.
DR   OMA; MYAHNIE; -.
DR   Proteomes; UP000001805; Chromosome 4, Linkage Group IV.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IBA:GO_Central.
DR   GO; GO:0005096; F:GTPase activator activity; IBA:GO_Central.
DR   GO; GO:0017137; F:Rab GTPase binding; IBA:GO_Central.
DR   GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IBA:GO_Central.
DR   InterPro; IPR000195; Rab-GTPase-TBC_dom.
DR   InterPro; IPR035969; Rab-GTPase_TBC_sf.
DR   Pfam; PF00566; RabGAP-TBC; 1.
DR   SMART; SM00164; TBC; 1.
DR   SUPFAM; SSF47923; SSF47923; 2.
DR   PROSITE; PS50086; TBC_RABGAP; 1.
PE   4: Predicted;
DR   PRODOM; Q7S8L1.
DR   SWISS-2DPAGE; Q7S8L1.
KW   Reference proteome {ECO:0000313|Proteomes:UP000001805}.
FT   DOMAIN          58..248
FT                   /note="Rab-GAP TBC"
FT                   /evidence="ECO:0000259|PROSITE:PS50086"
FT   REGION          79..99
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        80..97
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   412 AA;  46930 MW;  3EC0DCB4CE389DFF CRC64;
     MSQMDSGSSS ESGDSLSEKD EKVIIDPFFT EKEAAILTAC SQRDLTKLRD LAESRGGFLT
     DELRQQAWPI LLGLPPKPFD EDSSSSSYSS WESLPPHQDE DQVQLDVDRS FTYYPSHTSD
     SARSLQKSLL SSLILSVLRR HPYLHYFQGY HDISQVLLLV LPAHLRSPAL ARLSALRIRD
     FMLPNLQAAI AQLRLIPDIL RVSDPPLWRH LSGTEPFFAL SGTITMYAHD ITTLGEITRL
     FDVLLAREPV FSVYMFAAIV RSRREELFET PEDEPEMLHS ILSKLPQPLD LEGLIGDTVA
     LFEKYPPERL PSWRWGISGS SVLKTAREGF DKNKGATGQT MEDGKRFFER QVRELLWLER
     RDKAKKWMWK NRRPVRTLGL AVLVGIIAIL LRRAPGGPMA WVMGVVNRWW LT
//

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