(data stored in ACNUC15260 zone)

SWISSPROT: Q7TR35_MOUSE

ID   Q7TR35_MOUSE            Unreviewed;       314 AA.
AC   Q7TR35;
DT   01-OCT-2003, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2003, sequence version 1.
DT   08-MAY-2019, entry version 132.
DE   RecName: Full=Olfactory receptor {ECO:0000256|RuleBase:RU363047};
GN   Name=Olfr1148 {ECO:0000313|EMBL:AAP71563.1,
GN   ECO:0000313|Ensembl:ENSMUSP00000076778, ECO:0000313|MGI:MGI:3030982};
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
OC   Muroidea; Muridae; Murinae; Mus; Mus.
OX   NCBI_TaxID=10090 {ECO:0000313|EMBL:AAP71563.1};
RN   [1] {ECO:0000313|EMBL:AAP71563.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=14611657; DOI=10.1186/gb-2003-4-11-r71;
RA   Young J.M., Shykind B.M., Lane R.P., Tonnes-Priddy L., Ross J.A.,
RA   Walker M., Williams E.M., Trask B.J.;
RT   "Odorant receptor expressed sequence tags demonstrate olfactory
RT   expression of over 400 genes, extensive alternate splicing and unequal
RT   expression levels.";
RL   Genome Biol. 4:R71.1-R71.13(2003).
RN   [2] {ECO:0000313|EMBL:AAP71563.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Sanders K.;
RL   Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|Ensembl:ENSMUSP00000076778, ECO:0000313|Proteomes:UP000000589}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000076778,
RC   ECO:0000313|Proteomes:UP000000589};
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S.,
RA   She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W.,
RA   Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T.,
RA   Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J.,
RA   Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z.,
RA   Lindblad-Toh K., Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of
RT   the mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
RN   [4] {ECO:0000313|Ensembl:ENSMUSP00000076778}
RP   IDENTIFICATION.
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000076778};
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
RN   [5] {ECO:0000313|Ensembl:ENSMUSP00000149438}
RP   IDENTIFICATION.
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000149438};
RG   Ensembl;
RL   Submitted (DEC-2016) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell membrane
CC       {ECO:0000256|RuleBase:RU363047, ECO:0000256|SAAS:SAAS00857205};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU363047,
CC       ECO:0000256|SAAS:SAAS00857205}.
CC   -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC       {ECO:0000256|RuleBase:RU000688, ECO:0000256|SAAS:SAAS00857212}.
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DR   EMBL; AL929424; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AY318347; AAP71563.1; -; Genomic_DNA.
DR   RefSeq; NP_001011519.1; NM_001011519.1.
DR   STRING; 10090.ENSMUSP00000076778; -.
DR   Ensembl; ENSMUST00000077580; ENSMUSP00000076778; ENSMUSG00000061875.
DR   Ensembl; ENSMUST00000215230; ENSMUSP00000149438; ENSMUSG00000061875.
DR   GeneID; 258220; -.
DR   KEGG; mmu:258220; -.
DR   UCSC; uc008kot.1; mouse.
DR   CTD; 258220; -.
DR   MGI; MGI:3030982; Olfr1148.
DR   eggNOG; ENOG410YADW; LUCA.
DR   GeneTree; ENSGT00950000182762; -.
DR   HOGENOM; HOG000041364; -.
DR   KO; K04257; -.
DR   OMA; NMMEFIL; -.
DR   OrthoDB; 996729at2759; -.
DR   TreeFam; TF337350; -.
DR   Proteomes; UP000000589; Chromosome 2.
DR   Bgee; ENSMUSG00000061875; Expressed in 1 organ(s), highest expression level in spleen.
DR   GO; GO:0016021; C:integral component of membrane; ISA:MGI.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; ISA:MGI.
DR   GO; GO:0007186; P:G protein-coupled receptor signaling pathway; ISA:MGI.
DR   GO; GO:0007608; P:sensory perception of smell; ISA:MGI.
DR   InterPro; IPR000276; GPCR_Rhodpsn.
DR   InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR   InterPro; IPR000725; Olfact_rcpt.
DR   Pfam; PF13853; 7tm_4; 1.
DR   PRINTS; PR00237; GPCRRHODOPSN.
DR   PRINTS; PR00245; OLFACTORYR.
DR   PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR   PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q7TR35.
DR   SWISS-2DPAGE; Q7TR35.
KW   Cell membrane {ECO:0000256|RuleBase:RU363047,
KW   ECO:0000256|SAAS:SAAS00857207};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000589};
KW   G-protein coupled receptor {ECO:0000256|RuleBase:RU000688,
KW   ECO:0000256|SAAS:SAAS00857203};
KW   Membrane {ECO:0000256|RuleBase:RU363047,
KW   ECO:0000256|SAAS:SAAS00857208};
KW   Olfaction {ECO:0000256|RuleBase:RU363047,
KW   ECO:0000256|SAAS:SAAS00857209};
KW   Receptor {ECO:0000256|RuleBase:RU000688,
KW   ECO:0000256|SAAS:SAAS00857193, ECO:0000313|EMBL:AAP71563.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW   Sensory transduction {ECO:0000256|RuleBase:RU363047,
KW   ECO:0000256|SAAS:SAAS00857210};
KW   Transducer {ECO:0000256|RuleBase:RU000688,
KW   ECO:0000256|SAAS:SAAS00857213};
KW   Transmembrane {ECO:0000256|RuleBase:RU000688,
KW   ECO:0000256|SAAS:SAAS00857211};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU363047,
KW   ECO:0000256|SAAS:SAAS00857194}.
FT   TRANSMEM     32     55       Helical. {ECO:0000256|RuleBase:RU363047}.
FT   TRANSMEM     67     88       Helical. {ECO:0000256|RuleBase:RU363047}.
FT   TRANSMEM    100    126       Helical. {ECO:0000256|RuleBase:RU363047}.
FT   TRANSMEM    203    222       Helical. {ECO:0000256|RuleBase:RU363047}.
FT   TRANSMEM    243    267       Helical. {ECO:0000256|RuleBase:RU363047}.
FT   TRANSMEM    279    298       Helical. {ECO:0000256|RuleBase:RU363047}.
FT   DOMAIN       47    296       G_PROTEIN_RECEP_F1_2.
FT                                {ECO:0000259|PROSITE:PS50262}.
SQ   SEQUENCE   314 AA;  35027 MW;  79564B7BA269752D CRC64;
     MNHEELESIN NVSTVIQFVL IGFSDLPNLQ GFLFAVFSVV YIIILIGNFL IIIIISTDQA
     LQKPMYFFLA NFSSLEICYV SVTVPRILFN IGTQNRSISL MSCATQLCFF LVFGTTECLL
     LAVMSYDRYV AICNPLHYPL VMNPTKCTQL AAVSWLGGIP VQIGQTCQIF SMNFCNSYKI
     NHFFCDIPPI LTLACGNTSV HELSVYVVVM VVAAFPFILV LTSYSKIIAT ILRLPTAKGR
     GKAFSTCSSH LLVVLLFYGS ATVTYLRPKS MHSPGTDKLL SLFYTIVTPM FNPLIYSLRN
     KEVIAALRKL ILKK
//

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