(data stored in SCRATCH zone)

SWISSPROT: Q7WA55_BORPA

ID   Q7WA55_BORPA            Unreviewed;       285 AA.
AC   Q7WA55;
DT   01-OCT-2003, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2003, sequence version 1.
DT   08-MAY-2019, entry version 83.
DE   RecName: Full=Phosphatidate cytidylyltransferase {ECO:0000256|RuleBase:RU003938};
DE            EC=2.7.7.41 {ECO:0000256|RuleBase:RU003938};
GN   Name=cdsA {ECO:0000313|EMBL:CAE36834.1};
GN   OrderedLocusNames=BPP1532 {ECO:0000313|EMBL:CAE36834.1};
OS   Bordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC 13253).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Alcaligenaceae; Bordetella.
OX   NCBI_TaxID=257311 {ECO:0000313|Proteomes:UP000001421};
RN   [1] {ECO:0000313|Proteomes:UP000001421}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=12822 / ATCC BAA-587 / NCTC 13253
RC   {ECO:0000313|Proteomes:UP000001421};
RX   PubMed=12910271; DOI=10.1038/ng1227;
RA   Parkhill J., Sebaihia M., Preston A., Murphy L.D., Thomson N.,
RA   Harris D.E., Holden M.T., Churcher C.M., Bentley S.D., Mungall K.L.,
RA   Cerdeno-Tarraga A.M., Temple L., James K., Harris B., Quail M.A.,
RA   Achtman M., Atkin R., Baker S., Basham D., Bason N., Cherevach I.,
RA   Chillingworth T., Collins M., Cronin A., Davis P., Doggett J.,
RA   Feltwell T., Goble A., Hamlin N., Hauser H., Holroyd S., Jagels K.,
RA   Leather S., Moule S., Norberczak H., O'Neil S., Ormond D., Price C.,
RA   Rabbinowitsch E., Rutter S., Sanders M., Saunders D., Seeger K.,
RA   Sharp S., Simmonds M., Skelton J., Squares R., Squares S., Stevens K.,
RA   Unwin L., Whitehead S., Barrell B.G., Maskell D.J.;
RT   "Comparative analysis of the genome sequences of Bordetella pertussis,
RT   Bordetella parapertussis and Bordetella bronchiseptica.";
RL   Nat. Genet. 35:32-40(2003).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a 1,2-diacyl-sn-glycero-3-phosphate + CTP + H(+) = a CDP-
CC         1,2-diacyl-sn-glycerol + diphosphate; Xref=Rhea:RHEA:16229,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:33019, ChEBI:CHEBI:37563,
CC         ChEBI:CHEBI:58332, ChEBI:CHEBI:58608; EC=2.7.7.41;
CC         Evidence={ECO:0000256|RuleBase:RU003938};
CC   -!- PATHWAY: Phospholipid metabolism; CDP-diacylglycerol biosynthesis;
CC       CDP-diacylglycerol from sn-glycerol 3-phosphate: step 3/3.
CC       {ECO:0000256|RuleBase:RU003938}.
CC   -!- SIMILARITY: Belongs to the CDS family.
CC       {ECO:0000256|RuleBase:RU003938}.
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DR   EMBL; BX640427; CAE36834.1; -; Genomic_DNA.
DR   RefSeq; WP_010928080.1; NC_002928.3.
DR   EnsemblBacteria; CAE36834; CAE36834; BPP1532.
DR   KEGG; bpa:BPP1532; -.
DR   HOGENOM; HOG000006168; -.
DR   KO; K00981; -.
DR   OMA; GPKLWPR; -.
DR   BioCyc; BPAR257311:G1GSY-1572-MONOMER; -.
DR   UniPathway; UPA00557; UER00614.
DR   Proteomes; UP000001421; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004605; F:phosphatidate cytidylyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016024; P:CDP-diacylglycerol biosynthetic process; IEA:UniProtKB-UniPathway.
DR   InterPro; IPR000374; PC_trans.
DR   PROSITE; PS01315; CDS; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q7WA55.
DR   SWISS-2DPAGE; Q7WA55.
KW   Complete proteome {ECO:0000313|Proteomes:UP000001421};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Nucleotidyltransferase {ECO:0000256|RuleBase:RU003938,
KW   ECO:0000313|EMBL:CAE36834.1};
KW   Transferase {ECO:0000256|RuleBase:RU003938,
KW   ECO:0000313|EMBL:CAE36834.1};
KW   Transmembrane {ECO:0000256|RuleBase:RU003938,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     27     44       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     56     76       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     88    109       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    121    142       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    148    166       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    186    206       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    218    240       Helical. {ECO:0000256|SAM:Phobius}.
SQ   SEQUENCE   285 AA;  29727 MW;  ED378D0625E3A8EE CRC64;
     MLGQRIITAA VLLAVLALTL ALANPWWFVA LLALGAACAA WEWLRLTVRQ PPSGALCVGL
     AAALLAAMLA MAQAWIQGGV SGLRLEVWVG YWLTPAIVAV WLLGAGTAVA RGRADAPAAS
     LGWTLFAIPA VLAAWSVLAL MYLSRGGAYV VSLLALVWVA DIAAYFAGRA FGKRKLAPRV
     SPGKTVAGAV AGVLGAVAWI ALSSQWDGTY GQALVERWSW WLALPAAALL GVVSIVGDLF
     ESLLKRRAGR KDSSALLPGH GGVYDRIDAI LPVAPLALLM SGVLF
//

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