(data stored in SCRATCH zone)

SWISSPROT: Q7WAF6_BORPA

ID   Q7WAF6_BORPA            Unreviewed;       501 AA.
AC   Q7WAF6;
DT   01-OCT-2003, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2003, sequence version 1.
DT   28-FEB-2018, entry version 62.
DE   RecName: Full=Microcystinase C {ECO:0000256|PIRNR:PIRNR012702};
DE            Short=MlrC {ECO:0000256|PIRNR:PIRNR012702};
GN   OrderedLocusNames=BPP1421 {ECO:0000313|EMBL:CAE36723.1};
OS   Bordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC 13253).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Alcaligenaceae; Bordetella.
OX   NCBI_TaxID=257311 {ECO:0000313|Proteomes:UP000001421};
RN   [1] {ECO:0000313|Proteomes:UP000001421}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=12822 / ATCC BAA-587 / NCTC 13253
RC   {ECO:0000313|Proteomes:UP000001421};
RX   PubMed=12910271; DOI=10.1038/ng1227;
RA   Parkhill J., Sebaihia M., Preston A., Murphy L.D., Thomson N.,
RA   Harris D.E., Holden M.T., Churcher C.M., Bentley S.D., Mungall K.L.,
RA   Cerdeno-Tarraga A.M., Temple L., James K., Harris B., Quail M.A.,
RA   Achtman M., Atkin R., Baker S., Basham D., Bason N., Cherevach I.,
RA   Chillingworth T., Collins M., Cronin A., Davis P., Doggett J.,
RA   Feltwell T., Goble A., Hamlin N., Hauser H., Holroyd S., Jagels K.,
RA   Leather S., Moule S., Norberczak H., O'Neil S., Ormond D., Price C.,
RA   Rabbinowitsch E., Rutter S., Sanders M., Saunders D., Seeger K.,
RA   Sharp S., Simmonds M., Skelton J., Squares R., Squares S., Stevens K.,
RA   Unwin L., Whitehead S., Barrell B.G., Maskell D.J.;
RT   "Comparative analysis of the genome sequences of Bordetella pertussis,
RT   Bordetella parapertussis and Bordetella bronchiseptica.";
RL   Nat. Genet. 35:32-40(2003).
CC   -!- FUNCTION: Involved in peptidolytic degradation of cyclic
CC       heptapeptide hepatotoxin microcystin (MC).
CC       {ECO:0000256|PIRNR:PIRNR012702}.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|PIRNR:PIRNR012702};
CC       Note=Binds 1 zinc ion per subunit.
CC       {ECO:0000256|PIRNR:PIRNR012702};
CC   -!- SIMILARITY: Belongs to the peptidase M81 family.
CC       {ECO:0000256|PIRNR:PIRNR012702}.
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DR   EMBL; BX640427; CAE36723.1; -; Genomic_DNA.
DR   RefSeq; WP_010928029.1; NC_002928.3.
DR   EnsemblBacteria; CAE36723; CAE36723; BPP1421.
DR   KEGG; bpa:BPP1421; -.
DR   HOGENOM; HOG000267180; -.
DR   OMA; LHETNTF; -.
DR   BioCyc; BPAR257311:G1GSY-1461-MONOMER; -.
DR   Proteomes; UP000001421; Chromosome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR   InterPro; IPR009197; MlrC.
DR   InterPro; IPR010799; MlrC_C.
DR   InterPro; IPR015995; MlrC_N.
DR   Pfam; PF07364; DUF1485; 1.
DR   Pfam; PF07171; MlrC_C; 1.
DR   PIRSF; PIRSF012702; UCP012702; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q7WAF6.
DR   SWISS-2DPAGE; Q7WAF6.
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001421};
KW   Hydrolase {ECO:0000256|PIRNR:PIRNR012702};
KW   Metal-binding {ECO:0000256|PIRNR:PIRNR012702};
KW   Metalloprotease {ECO:0000256|PIRNR:PIRNR012702};
KW   Protease {ECO:0000256|PIRNR:PIRNR012702}.
FT   DOMAIN        3    292       DUF1485. {ECO:0000259|Pfam:PF07364}.
FT   DOMAIN      305    482       MlrC_C. {ECO:0000259|Pfam:PF07171}.
FT   COILED      257    277       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   501 AA;  53038 MW;  E6F238D54C16B09D CRC64;
     MHILVAGFQH ETNTFAPSKA GYDNFLRGEG FPALVRGDDL LALRAVNIPA GGFLNAALAD
     GHSVHPVLWA GASPSAHVTR DAFERIAGEI EAAARAGRYD AVYLDLHGAM VTEHHDDGEG
     ELLRRLRDAV GPATPIVASL DLHANVTRAM LAHASALVAY HTYPHVDMAD TGARAAALLQ
     ARAQAGKHWH GAARRLPFLI PINGMCTQLE PARGVYALLA ELERSEPGIA SLSCALGFPA
     ADFPECGPVV WAHGPDRDAV ERAVQTLADR IAGLEAQWAP DFLAPDEAIR QARQLAQGAR
     RPVVIADTQD NPGAGGDANT TGMLRALIDA DADNAAIGLM CDPQAVAQAL AAGVGKCVRL
     RLGGQSGVAG DAPCEAEFIV EHQSDGKTRY DGPMMHGMAA DLGPTVCLRH RGVRVIVSSN
     KSQTLDRNLI RLGGIDPEDL AILVVKSSVH FRADFEPIAH AVLIAKAPGP MQADPADLPW
     TRLAPGMRTR PRGRPFVPAR P
//

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