(data stored in ACNUC1104 zone)

SWISSPROT: Q827Y7_STRAW

ID   Q827Y7_STRAW            Unreviewed;       505 AA.
AC   Q827Y7;
DT   01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT   01-JUN-2003, sequence version 1.
DT   08-MAY-2019, entry version 98.
DE   SubName: Full=Putative multidrug resistance efflux protein {ECO:0000313|EMBL:BAC74493.1};
GN   ORFNames=SAVERM_6782 {ECO:0000313|EMBL:BAC74493.1};
OS   Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 /
OS   NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680).
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces.
OX   NCBI_TaxID=227882 {ECO:0000313|EMBL:BAC74493.1, ECO:0000313|Proteomes:UP000000428};
RN   [1] {ECO:0000313|EMBL:BAC74493.1, ECO:0000313|Proteomes:UP000000428}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 /
RC   NRRL 8165 / MA-4680 {ECO:0000313|Proteomes:UP000000428};
RX   PubMed=11572948; DOI=10.1073/pnas.211433198;
RA   Omura S., Ikeda H., Ishikawa J., Hanamoto A., Takahashi C.,
RA   Shinose M., Takahashi Y., Horikawa H., Nakazawa H., Osonoe T.,
RA   Kikuchi H., Shiba T., Sakaki Y., Hattori M.;
RT   "Genome sequence of an industrial microorganism Streptomyces
RT   avermitilis: deducing the ability of producing secondary
RT   metabolites.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:12215-12220(2001).
RN   [2] {ECO:0000313|EMBL:BAC74493.1, ECO:0000313|Proteomes:UP000000428}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 /
RC   NRRL 8165 / MA-4680 {ECO:0000313|Proteomes:UP000000428};
RX   PubMed=12692562; DOI=10.1038/nbt820;
RA   Ikeda H., Ishikawa J., Hanamoto A., Shinose M., Kikuchi H., Shiba T.,
RA   Sakaki Y., Hattori M., Omura S.;
RT   "Complete genome sequence and comparative analysis of the industrial
RT   microorganism Streptomyces avermitilis.";
RL   Nat. Biotechnol. 21:526-531(2003).
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DR   EMBL; BA000030; BAC74493.1; -; Genomic_DNA.
DR   RefSeq; WP_010988181.1; NZ_JZJK01000082.1.
DR   STRING; 227882.SAV_6782; -.
DR   EnsemblBacteria; BAC74493; BAC74493; SAVERM_6782.
DR   KEGG; sma:SAVERM_6782; -.
DR   eggNOG; COG0477; LUCA.
DR   HOGENOM; HOG000239124; -.
DR   KO; K08167; -.
DR   OMA; FHDPRER; -.
DR   OrthoDB; 626204at2; -.
DR   BioCyc; SAVE227882:G1G23-7089-MONOMER; -.
DR   Proteomes; UP000000428; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   CDD; cd06174; MFS; 1.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   4: Predicted;
DR   PRODOM; Q827Y7.
DR   SWISS-2DPAGE; Q827Y7.
KW   Complete proteome {ECO:0000313|Proteomes:UP000000428};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000428};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     20     46       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     58     76       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     88    107       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    113    134       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    146    168       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    174    196       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    208    227       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    233    254       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    275    296       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    316    333       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    340    359       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    365    391       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    412    429       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    476    498       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       22    502       MFS. {ECO:0000259|PROSITE:PS50850}.
SQ   SEQUENCE   505 AA;  51391 MW;  54532DC34D85C6F3 CRC64;
     MTSTLRPASV AEVEQRPGRW LALSVLVLAV LLVAVDATVL GLATPYISED LKPSGTQLLW
     IGDVYSFVIA GLLVSMGSLG DRIGRKKLLL IGSTAFGAIS VLNAYATTPE LMILARALLG
     VAGATLMPAT LALIRNLFHD PRERSFAIGV WGATASAGTA VGPVVGGFLL GHFWWGSVFL
     INLPVMIVLV LVGIRLLPES RNPDPGPWDL SSVVLSLVGM IGIVYAVKEA ASHGPSLDAL
     AAGALGAAAL FGFVRRQLVM PKPLLDMRLF RNRGFSAAVL ADLLTVLGMS GLIFFLSQYL
     QLVQGRPPFE AGLAEVPAAV GAVAAGLAAG RAARRYSVRA VVSGGLAAVG LALAALTLLS
     ESTGYPLLGT ALLVVGVGAG FSFTVTADVI LSSVPKDQAG AAAAVSETAY ELGAALGIAL
     LGSIVTGVYR DFHGPAGTPA QAHESLGGAV ESTAGLPAHT AEAVLSSARA AFVDGLALAA
     GAGAAVLLAT AVAAWFLLRG QKLEA
//

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